Peracute Infection of Swine With Salmonella

It has recently been experimentally demonstrated that pigs exposed naturally to Salmonella on the floor of abattoir holding pens can become infected between two and six hours after being placed in the pens. In addition we have demonstrated that tonsillar tissue are almost immediately culture positive following such exposure under experimental conditions. The objective of this study was to determine the shortest amount of time necessary for infection of selected tissues and to determine if the tonsil served as a route for Salmonella entry into lymphoid tissues draining the tonsil. Forty-four Salmonella-negative, market age pigs (90 to 110 kg) were fasted overnight and exposed to approximately 2 X 106 Salmonella enterica serotype Typhimurium strain X4232 (nalidixic acid resistant). The bacteria were mixed with a fecal slurry and the slurry spread on the floor of the pens. Pigs were euthanized at 15, 30, 45, 60 and 120 minutes following initial exposure. Tonsil of the soft palate, medial retropharyngeal lymph node, ileocecal lymph node, a five centimeter section of the terminal ileum, cecal contents and 100 ml of blood were cultured for Salmonella. Strain X4232 was isolated from 98 % (43/44) of tonsils. Strain X4232 was isolated from the ileocecal lymph node within 45 minutes (2/9 pigs), terminal ileum within 15 minutes (1/9 pigs), cecal contents within 15 minutes (1/9 pigs), and blood within 45 minutes (1/9 pigs). Strain X4232 was not recovered from the medial retropharyngeal lymph node, indicating that the organism did not move rapidly into this node from the tonsil of the soft palate. Results of this study indicate that Salmonella can be recovered from selected tissues in market age swine in less than the normal two hour abattoir holding time

Eigenstates of a Small Josephson Junction Coupled to a Resonant Cavity

We carry out a quantum-mechanical analysis of a small Josephson junction coupled to a single-mode resonant cavity. We find that the eigenstates of the combined junction-cavity system are strongly entangled only when the gate voltage applied at one of the superconducting islands is tuned to certain special values. One such value corresponds to the resonant absorption of a single photon by Cooper pairs in the junction. Another special value corresponds to a {\em two-photon} absorption process. Near the single-photon resonant absorption, the system is accurately described by a simplified model in which only the lowest two levels of the Josephson junction are retained in the Hamiltonian matrix. We noticed that this approximation does not work very well as the number of photons in the resonator increases. Our system shows also the phenomenon of ``collapse and revival'' under suitable initial conditions, and our full numerical solution agrees with the two level approximation result.Comment: 7 pages, and 6 figures. To be published in Phys. Rev.

Resonant-Cavity-Induced Phase Locking and Voltage Steps in a Josephson Array

We describe a simple dynamical model for an underdamped Josephson junction array coupled to a resonant cavity. From numerical solutions of the model in one dimension, we find that (i) current-voltage characteristics of the array have self-induced resonant steps (SIRS), (ii) at fixed disorder and coupling strength, the array locks into a coherent, periodic state above a critical number of active Josephson junctions, and (iii) when $N_a$ active junctions are synchronized on an SIRS, the energy emitted into the resonant cavity is quadratic with $N_a$. All three features are in agreement with a recent experiment [Barbara {\it et al}, Phys. Rev. Lett. {\bf 82}, 1963 (1999)]}.Comment: 4 pages, 3 eps figures included. Submitted to PRB Rapid Com

Dynamics of a Josephson Array in a Resonant Cavity

We derive dynamical equations for a Josephson array coupled to a resonant cavity by applying the Heisenberg equations of motion to a model Hamiltonian described by us earlier [Phys. Rev. B {\bf 63}, 144522 (2001); Phys. Rev. B {\bf 64}, 179902 (E)]. By means of a canonical transformation, we also show that, in the absence of an applied current and dissipation, our model reduces to one described by Shnirman {\it et al} [Phys. Rev. Lett. {\bf 79}, 2371 (1997)] for coupled qubits, and that it corresponds to a capacitive coupling between the array and the cavity mode. From extensive numerical solutions of the model in one dimension, we find that the array locks into a coherent, periodic state above a critical number of active junctions, that the current-voltage characteristics of the array have self-induced resonant steps (SIRS's), that when $N_a$ active junctions are synchronized on a SIRS, the energy emitted into the resonant cavity is quadratic in $N_a$, and that when a fixed number of junctions is biased on a SIRS, the energy is linear in the input power. All these results are in agreement with recent experiments. By choosing the initial conditions carefully, we can drive the array into any of a variety of different integer SIRS's. We tentatively identify terms in the equations of motion which give rise to both the SIRS's and the coherence threshold. We also find higher-order integer SIRS's and fractional SIRS's in some simulations. We conclude that a resonant cavity can produce threshold behavior and SIRS's even in a one-dimensional array with appropriate experimental parameters, and that the experimental data, including the coherent emission, can be understood from classical equations of motion.Comment: 15 pages, 10 eps figures, submitted to Phys. Rev.

Portrayal of organ donation and transplantation on American primetime television

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/86819/1/j.1399-0012.2011.01427.x.pd

Benevolent characteristics promote cooperative behaviour among humans

Cooperation is fundamental to the evolution of human society. We regularly observe cooperative behaviour in everyday life and in controlled experiments with anonymous people, even though standard economic models predict that they should deviate from the collective interest and act so as to maximise their own individual payoff. However, there is typically heterogeneity across subjects: some may cooperate, while others may not. Since individual factors promoting cooperation could be used by institutions to indirectly prime cooperation, this heterogeneity raises the important question of who these cooperators are. We have conducted a series of experiments to study whether benevolence, defined as a unilateral act of paying a cost to increase the welfare of someone else beyond one's own, is related to cooperation in a subsequent one-shot anonymous Prisoner's dilemma. Contrary to the predictions of the widely used inequity aversion models, we find that benevolence does exist and a large majority of people behave this way. We also find benevolence to be correlated with cooperative behaviour. Finally, we show a causal link between benevolence and cooperation: priming people to think positively about benevolent behaviour makes them significantly more cooperative than priming them to think malevolently. Thus benevolent people exist and cooperate more

Recent Developments and Applications of the HYDRUS Computer Software Packages

The HYDRUS-1D and HYDRUS (2D/3D) computer software packages are widely used finite-element models for simulating the one- and two- or three-dimensional movement of water, heat, and multiple solutes in variably saturated media, respectively. In 2008, Šimůnek et al. (2008b) described the entire history of the development of the various HYDRUS programs and related models and tools such as STANMOD, RETC, ROSETTA, UNSODA, UNSATCHEM, HP1, and others. The objective of this manuscript is to review selected capabilities of HYDRUS that have been implemented since 2008. Our review is not limited to listing additional processes that were implemented in the standard computational modules, but also describes many new standard and nonstandard specialized add-on modules that significantly expanded the capabilities of the two software packages. We also review additional capabilities that have been incorporated into the graphical user interface (GUI) that supports the use of HYDRUS (2D/3D). Another objective of this manuscript is to review selected applications of the HYDRUS models such as evaluation of various irrigation schemes, evaluation of the effects of plant water uptake on groundwater recharge, assessing the transport of particle-like substances in the subsurface, and using the models in conjunction with various geophysical methods

Giving Leads to Happiness in Young Children

Evolutionary models of cooperation require proximate mechanisms that sustain prosociality despite inherent costs to individuals. The “warm glow” that often follows prosocial acts could provide one such mechanism; if so, these emotional benefits may be observable very early in development. Consistent with this hypothesis, the present study finds that before the age of two, toddlers exhibit greater happiness when giving treats to others than receiving treats themselves. Further, children are happier after engaging in costly giving – forfeiting their own resources – than when giving the same treat at no cost. By documenting the emotionally rewarding properties of costly prosocial behavior among toddlers, this research provides initial support for the claim that experiencing positive emotions when giving to others is a proximate mechanism for human cooperation

Between-group competition elicits within-group cooperation in children

Aggressive interactions between groups are frequent in human societies and can bear significant fitness costs and benefits (e.g. death or access to resources). During between-group competitive interactions, more cohesive groups (i.e. groups formed by individuals who cooperate in group defence) should out-perform less cohesive groups, other factors being equal (e.g. group size). The cost/benefit of between-group competition are thought to have driven correlated evolution of traits that favour between-group aggression and within-group cooperation (e.g. parochial altruism). Our aim was to analyse whether the proximate relationship between between-group competition and within-group cooperation is found in 3–10 years old children and the developmental trajectory of such a relationship. We used a large cohort of children (n = 120) and tested whether simulated between-group competition increased within-group cooperation (i.e. how much of a resource children were giving to their group companions) in two experiments. We found greater within-group cooperation when groups of four children were competing with other groups then in the control condition (no between-group competition). Within-group cooperation increased with age. Our study suggests that parochial altruism and in-group/out-group biases emerge early during the course of human development