7 research outputs found
Uranium Recovery From Composite UF Reduction Bomb Wastes
A number of techniques have been investigated on a laboratory-scale for separating uranium from fluorides during the recovery of uranium from UF4 reduction bomb wastes (C-oxide) by an HCl leach - NH4OH precipitation process. Among these are included adsorption of fluorides from filtered leach liquors, fractional precipitation of fluorides and uranium, complexing of fluorides into forms soluble in slightly acid solutions, and fluoride volatilization from the uranium concentrate. Solubility studies of CaF2 and MgF2 in aqueous hydrochloric acid at various acidities and temperatures were also conducted. A description of the production-scale processing of C-oxide in the FMPC scrap plant has been included
Alternatively spliced variants of the 5’-UTR of the ARPC2 mRNA regulate translation by an internal ribosome entry site (IRES) harboring a guanine-quadruplex motif
Determinants of Left Atrial Volume in Patients with Atrial Fibrillation
<div><p>Introduction</p><p>Left atrial (LA) enlargement is an important risk factor for incident stroke and a key determinant for the success of rhythm control strategies in patients with atrial fibrillation (AF). However, factors associated with LA volume in AF patients remain poorly understood.</p><p>Methods</p><p>Patients with paroxysmal or persistent AF were enrolled in this study. Real time 3-D echocardiography was performed in all participants and analyzed offline in a standardized manner. We performed stepwise backward linear regression analyses using a broad set of clinical parameters to determine independent correlates for 3-D LA volume.</p><p>Results</p><p>We included 210 patients (70.9% male, mean age 61±11years). Paroxysmal and persistent AF were present in 95 (45%) and 115 (55%) patients, respectively. Overall, 115 (55%) had hypertension, 11 (5%) had diabetes, and 18 (9%) had ischemic heart disease. Mean indexed LA volume was 36±12ml/m<sup>2</sup>. In multivariable models, significant associations were found for female sex (β coefficient -10.51 (95% confidence interval (CI) -17.85;-3.16), p = 0.0053), undergoing cardioversion (β 11.95 (CI 5.15; 18.74), p = 0.0006), diabetes (β 14.23 (CI 2.36; 26.10), p = 0.019), body surface area (BSA) (β 34.21 (CI 19.30; 49.12), p<0.0001), glomerular filtration rate (β -0.21 (CI -0.36; -0.06), p = 0.0064) and plasma levels of NT-pro brain natriuretic peptide (NT-proBNP) (β 6.79 (CI 4.05; 9.52), p<0.0001), but not age (p = 0.59) or hypertension (p = 0.42). Our final model explained 52% of the LA volume variability.</p><p>Conclusions</p><p>In patients with AF, the most important correlates with LA volume are sex, BSA, diabetes, renal function and NT-proBNP, but not age or hypertension. These results may help to refine rhythm control strategies in AF patients.</p></div
Independent determinants of left atrial volume in AF patients.
<p>SE = Standard error; SD = Standard deviation; y/n = yes / no; ECV = Electrical cardioversion; NT-proBNP = N-terminal-pro B-type natriuretic peptide; eGFR = Estimated glomerular filtration rate. R2 is reported for the final multivariable model. The β (95% confidence intervals) represents the increase or decrease in left atrial volume (mL) per unit change of the specific covariate. The multivariable model also included age, atrial fibrillation type (paroxysmal vs. persistent), resting heart rate, left ventricular ejection fraction, left ventricular mass, high-sensitivity troponin T ≥15ng/mL, interleukin-6, history of heart failure, arterial hypertension, moderate or severe mitral regurgitation and sleep apnea syndrome. All above presented variables selected by the stepwise backward regression model were significant at the ≤0.05 level. * log-transformed variables. <sup>†</sup> Estimated by the CKD-EPI formula including creatinine and cystatin C.</p
Baseline characteristics according to underlying atrial fibrillation type.
<p>Baseline characteristics according to underlying atrial fibrillation type.</p