2,724 research outputs found
Ionospheric refraction effects on orbit determination using the orbit determination error analysis system
The influence of ionospheric refraction on orbit determination was studied through the use of the Orbit Determination Error Analysis System (ODEAS). The results of a study of the orbital state estimate errors due to the ionospheric refraction corrections, particularly for measurements involving spacecraft-to-spacecraft tracking links, are presented. In current operational practice at the Goddard Space Flight Center (GSFC) Flight Dynamics Facility (FDF), the ionospheric refraction effects on the tracking measurements are modeled in the Goddard Trajectory Determination System (GTDS) using the Bent ionospheric model. While GTDS has the capability of incorporating the ionospheric refraction effects for measurements involving ground-to-spacecraft tracking links, such as those generated by the Ground Spaceflight Tracking and Data Network (GSTDN), it does not have the capability to incorporate the refraction effects for spacecraft-to-spacecraft tracking links for measurements generated by the Tracking and Data Relay Satellite System (TDRSS). The lack of this particular capability in GTDS raised some concern about the achievable accuracy of the estimated orbit for certain classes of spacecraft missions that require high-precision orbits. Using an enhanced research version of GTDS, some efforts have already been made to assess the importance of the spacecraft-to-spacecraft ionospheric refraction corrections in an orbit determination process. While these studies were performed using simulated data or real tracking data in definitive orbit determination modes, the study results presented here were obtained by means of covariance analysis simulating the weighted least-squares method used in orbit determination
Evidence For Ecological Character Displacement In Western American Catostomid Fishes
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/137612/1/evo04742.pd
Systematic analysis of off-target effects in an RNAi screen reveals microRNAs affecting sensitivity to TRAIL-induced apoptosis.
BACKGROUND: RNA inhibition by siRNAs is a frequently used approach to identify genes required for specific biological processes. However RNAi screening using siRNAs is hampered by non-specific or off target effects of the siRNAs, making it difficult to separate genuine hits from false positives. It is thought that many of the off-target effects seen in RNAi experiments are due to siRNAs acting as microRNAs (miRNAs), causing a reduction in gene expression of unintended targets via matches to the 6 or 7 nt 'seed' sequence. We have conducted a careful examination of off-target effects during an siRNA screen for novel regulators of the TRAIL apoptosis induction pathway(s). RESULTS: We identified 3 hexamers and 3 heptamer seed sequences that appeared multiple times in the top twenty siRNAs in the TRAIL apoptosis screen. Using a novel statistical enrichment approach, we systematically identified a further 17 hexamer and 13 heptamer seed sequences enriched in high scoring siRNAs. The presence of one of these seeds sequences (which could explain 6 of 8 confirmed off-target effects) is sufficient to elicit a phenotype. Three of these seed sequences appear in the human miRNAs miR-26a, miR-145 and miR-384. Transfection of mimics of these miRNAs protects several cell types from TRAIL-induced cell death. CONCLUSIONS: We have demonstrated a role for miR-26a, miR-145 and miR-26a in TRAIL-induced apoptosis. Further these results show that RNAi screening enriches for siRNAs with relevant off-target effects. Some of these effects can be identified by the over-representation of certain seed sequences in high-scoring siRNAs and we demonstrate the usefulness of such systematic analysis of enriched seed sequences
The RMS Survey: Ammonia and water maser analysis of massive star forming regions
The Red MSX Source (RMS) survey has identified a sample of ~1200 massive
young stellar objects (MYSOs), compact and ultra compact HII regions from a
sample of ~2000 MSX and 2MASS colour selected sources. We have used the 100 m
Green Bank telescope to search for 22-24 GHz water maser and ammonia (1,1),
(2,2) and (3,3) emission towards ~600 RMS sources located within the northern
Galactic plane. We have identified 308 H2O masers which corresponds to an
overall detection rate of ~50%. Abridged: We detect ammonia emission towards
479 of these massive young stars, which corresponds to ~80%. Ammonia is an
excellent probe of high density gas allowing us to measure key parameters such
as gas temperatures, opacities, and column densities, as well as providing an
insight into the gas kinematics. The average kinetic temperature, FWHM line
width and total NH3 column density for the sample are approximately 22 K, 2
km/s and 2x10^{15} cm^{-2}, respectively. We find that the NH3 (1,1) line width
and kinetic temperature are correlated with luminosity and finding no
underlying dependence of these parameters on the evolutionary phase of the
embedded sources, we conclude that the observed trends in the derived
parameters are more likely to be due to the energy output of the central source
and/or the line width-clump mass relationship. The velocities of the peak H2O
masers and the NH3 emission are in excellent agreement with each other, which
would strongly suggest an association between the dense gas and the maser
emission. Moreover, we find the bolometric luminosity of the embedded source
and the isotropic luminosity of the H2O maser are also correlated. We conclude
from the correlations of the cloud and water maser velocities and the
bolometric and maser luminosity that there is a strong dynamical relationship
between the embedded young massive star and the H2O maser.Comment: 17 pages and 17 figures and 8 tables. Tables\,2 and 5 and full
versions of Figs. 3 and 7 are only available in electronic form at the CDS
via anonymous ftp to cdsarc.u-strasbg.fr (130.79.125.5) or via
http://cdsweb.u-strasbg.fr/cgi-bin/qcat?J/A+A
A New Spectroscopic and Photometric Analysis of the Transiting Planet Systems TrES-3 and TrES-4
We report new spectroscopic and photometric observations of the parent stars
of the recently discovered transiting planets TrES-3 and TrES-4. A detailed
abundance analysis based on high-resolution spectra yields [Fe/H] , K, and for TrES-3,
and [Fe/H] , K, and for TrES-4. The accuracy of the effective temperatures is supported
by a number of independent consistency checks. The spectroscopic orbital
solution for TrES-3 is improved with our new radial-velocity measurements of
that system, as are the light-curve parameters for both systems based on newly
acquired photometry for TrES-3 and a reanalysis of existing photometry for
TrES-4. We have redetermined the stellar parameters taking advantage of the
strong constraint provided by the light curves in the form of the normalized
separation (related to the stellar density) in conjunction with our
new temperatures and metallicities. The masses and radii we derive are
M_\star=0.928_{-0.048}^{+0.028} M_{\sun},R_\star = 0.829_{-0.022}^{+0.015}
R_{\sun}, and M_\star = 1.404_{-0.134}^{+0.066} M_{\sun},
R_\star=1.846_{-0.087}^{+0.096} R_{\sun} for TrES-3 and TrES-4, respectively.
With these revised stellar parameters we obtain improved values for the
planetary masses and radii. We find , for TrES-3, and
, for TrES-4. We confirm TrES-4 as the planet with the largest
radius among the currently known transiting hot Jupiters.Comment: 42 pages, 10 tables, 8 figures. Accepted for publication in the
Astrophysical Journa
The second US Naval Observatory CCD Astrograph Catalog (UCAC2)
The second USNO CCD Astrograph Catalog, UCAC2 was released in July 2003.
Positions and proper motions for 48,330,571 sources (mostly stars) are
available on 3 CDs, supplemented with 2MASS photometry for 99.5% of the
sources. The catalog covers the sky area from -90 to +40 degrees declination,
going up to +52 in some areas; this completely supersedes the UCAC1 released in
2001. Current epoch positions are obtained from observations with the USNO
8-inch Twin Astrograph equipped with a 4k CCD camera. The precision of the
positions are 15 to 70 mas, depending on magnitude, with estimated systematic
errors of 10 mas or below. Proper motions are derived by utilizing over 140
ground-and space-based catalogs, including Hipparcos/Tycho, the AC2000.2, as
well as yet unpublished re-measures of the AGK2 plates and scans from the NPM
and SPM plates. Proper motion errors are about 1 to 3 mas/yr for stars to 12th
magnitude, and about 4 to 7 mas/yr for fainter stars to 16th magnitude. The
observational data, astrometric reductions, results, and important information
for the users of this catalog are presented.Comment: accepted by AJ, AAS LaTeX, 14 figures, 10 table
The WKB Approximation without Divergences
In this paper, the WKB approximation to the scattering problem is developed
without the divergences which usually appear at the classical turning points. A
detailed procedure of complexification is shown to generate results identical
to the usual WKB prescription but without the cumbersome connection formulas.Comment: 13 pages, TeX file, to appear in Int. J. Theor. Phy
Filter parameter tuning analysis for operational orbit determination support
The use of an extended Kalman filter (EKF) for operational orbit determination support is being considered by the Goddard Space Flight Center (GSFC) Flight Dynamics Division (FDD). To support that investigation, analysis was performed to determine how an EKF can be tuned for operational support of a set of earth-orbiting spacecraft. The objectives of this analysis were to design and test a general purpose scheme for filter tuning, evaluate the solution accuracies, and develop practical methods to test the consistency of the EKF solutions in an operational environment. The filter was found to be easily tuned to produce estimates that were consistent, agreed with results from batch estimation, and compared well among the common parameters estimated for several spacecraft. The analysis indicates that there is not a sharply defined 'best' tunable parameter set, especially when considering only the position estimates over the data arc. The comparison of the EKF estimates for the user spacecraft showed that the filter is capable of high-accuracy results and can easily meet the current accuracy requirements for the spacecraft included in the investigation. The conclusion is that the EKF is a viable option for FDD operational support
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