2,716 research outputs found

    Ionospheric refraction effects on orbit determination using the orbit determination error analysis system

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    The influence of ionospheric refraction on orbit determination was studied through the use of the Orbit Determination Error Analysis System (ODEAS). The results of a study of the orbital state estimate errors due to the ionospheric refraction corrections, particularly for measurements involving spacecraft-to-spacecraft tracking links, are presented. In current operational practice at the Goddard Space Flight Center (GSFC) Flight Dynamics Facility (FDF), the ionospheric refraction effects on the tracking measurements are modeled in the Goddard Trajectory Determination System (GTDS) using the Bent ionospheric model. While GTDS has the capability of incorporating the ionospheric refraction effects for measurements involving ground-to-spacecraft tracking links, such as those generated by the Ground Spaceflight Tracking and Data Network (GSTDN), it does not have the capability to incorporate the refraction effects for spacecraft-to-spacecraft tracking links for measurements generated by the Tracking and Data Relay Satellite System (TDRSS). The lack of this particular capability in GTDS raised some concern about the achievable accuracy of the estimated orbit for certain classes of spacecraft missions that require high-precision orbits. Using an enhanced research version of GTDS, some efforts have already been made to assess the importance of the spacecraft-to-spacecraft ionospheric refraction corrections in an orbit determination process. While these studies were performed using simulated data or real tracking data in definitive orbit determination modes, the study results presented here were obtained by means of covariance analysis simulating the weighted least-squares method used in orbit determination

    Evidence For Ecological Character Displacement In Western American Catostomid Fishes

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/137612/1/evo04742.pd

    Systematic analysis of off-target effects in an RNAi screen reveals microRNAs affecting sensitivity to TRAIL-induced apoptosis.

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    BACKGROUND: RNA inhibition by siRNAs is a frequently used approach to identify genes required for specific biological processes. However RNAi screening using siRNAs is hampered by non-specific or off target effects of the siRNAs, making it difficult to separate genuine hits from false positives. It is thought that many of the off-target effects seen in RNAi experiments are due to siRNAs acting as microRNAs (miRNAs), causing a reduction in gene expression of unintended targets via matches to the 6 or 7 nt 'seed' sequence. We have conducted a careful examination of off-target effects during an siRNA screen for novel regulators of the TRAIL apoptosis induction pathway(s). RESULTS: We identified 3 hexamers and 3 heptamer seed sequences that appeared multiple times in the top twenty siRNAs in the TRAIL apoptosis screen. Using a novel statistical enrichment approach, we systematically identified a further 17 hexamer and 13 heptamer seed sequences enriched in high scoring siRNAs. The presence of one of these seeds sequences (which could explain 6 of 8 confirmed off-target effects) is sufficient to elicit a phenotype. Three of these seed sequences appear in the human miRNAs miR-26a, miR-145 and miR-384. Transfection of mimics of these miRNAs protects several cell types from TRAIL-induced cell death. CONCLUSIONS: We have demonstrated a role for miR-26a, miR-145 and miR-26a in TRAIL-induced apoptosis. Further these results show that RNAi screening enriches for siRNAs with relevant off-target effects. Some of these effects can be identified by the over-representation of certain seed sequences in high-scoring siRNAs and we demonstrate the usefulness of such systematic analysis of enriched seed sequences

    The RMS Survey: Ammonia and water maser analysis of massive star forming regions

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    The Red MSX Source (RMS) survey has identified a sample of ~1200 massive young stellar objects (MYSOs), compact and ultra compact HII regions from a sample of ~2000 MSX and 2MASS colour selected sources. We have used the 100 m Green Bank telescope to search for 22-24 GHz water maser and ammonia (1,1), (2,2) and (3,3) emission towards ~600 RMS sources located within the northern Galactic plane. We have identified 308 H2O masers which corresponds to an overall detection rate of ~50%. Abridged: We detect ammonia emission towards 479 of these massive young stars, which corresponds to ~80%. Ammonia is an excellent probe of high density gas allowing us to measure key parameters such as gas temperatures, opacities, and column densities, as well as providing an insight into the gas kinematics. The average kinetic temperature, FWHM line width and total NH3 column density for the sample are approximately 22 K, 2 km/s and 2x10^{15} cm^{-2}, respectively. We find that the NH3 (1,1) line width and kinetic temperature are correlated with luminosity and finding no underlying dependence of these parameters on the evolutionary phase of the embedded sources, we conclude that the observed trends in the derived parameters are more likely to be due to the energy output of the central source and/or the line width-clump mass relationship. The velocities of the peak H2O masers and the NH3 emission are in excellent agreement with each other, which would strongly suggest an association between the dense gas and the maser emission. Moreover, we find the bolometric luminosity of the embedded source and the isotropic luminosity of the H2O maser are also correlated. We conclude from the correlations of the cloud and water maser velocities and the bolometric and maser luminosity that there is a strong dynamical relationship between the embedded young massive star and the H2O maser.Comment: 17 pages and 17 figures and 8 tables. Tables\,2 and 5 and full versions of Figs. 3 and 7 are only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.125.5) or via http://cdsweb.u-strasbg.fr/cgi-bin/qcat?J/A+A

    A New Spectroscopic and Photometric Analysis of the Transiting Planet Systems TrES-3 and TrES-4

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    We report new spectroscopic and photometric observations of the parent stars of the recently discovered transiting planets TrES-3 and TrES-4. A detailed abundance analysis based on high-resolution spectra yields [Fe/H] =0.19±0.08= -0.19\pm 0.08, Teff=5650±75T_\mathrm{eff} = 5650\pm 75 K, and logg=4.4±0.1\log g = 4.4\pm 0.1 for TrES-3, and [Fe/H] =+0.14±0.09= +0.14\pm 0.09, Teff=6200±75T_\mathrm{eff} = 6200\pm 75 K, and logg=4.0±0.1\log g = 4.0\pm0.1 for TrES-4. The accuracy of the effective temperatures is supported by a number of independent consistency checks. The spectroscopic orbital solution for TrES-3 is improved with our new radial-velocity measurements of that system, as are the light-curve parameters for both systems based on newly acquired photometry for TrES-3 and a reanalysis of existing photometry for TrES-4. We have redetermined the stellar parameters taking advantage of the strong constraint provided by the light curves in the form of the normalized separation a/Ra/R_\star (related to the stellar density) in conjunction with our new temperatures and metallicities. The masses and radii we derive are M_\star=0.928_{-0.048}^{+0.028} M_{\sun},R_\star = 0.829_{-0.022}^{+0.015} R_{\sun}, and M_\star = 1.404_{-0.134}^{+0.066} M_{\sun}, R_\star=1.846_{-0.087}^{+0.096} R_{\sun} for TrES-3 and TrES-4, respectively. With these revised stellar parameters we obtain improved values for the planetary masses and radii. We find Mp=1.9100.080+0.075MJupM_p = 1.910_{-0.080}^{+0.075} M_\mathrm{Jup}, Rp=1.3360.036+0.031RJupR_p=1.336_{-0.036}^{+0.031} R_\mathrm{Jup} for TrES-3, and Mp=0.925±0.082MJupM_p=0.925 \pm 0.082 M_\mathrm{Jup}, Rp=1.7830.086+0.093RJupR_p=1.783_{-0.086}^{+0.093} R_\mathrm{Jup} for TrES-4. We confirm TrES-4 as the planet with the largest radius among the currently known transiting hot Jupiters.Comment: 42 pages, 10 tables, 8 figures. Accepted for publication in the Astrophysical Journa

    The second US Naval Observatory CCD Astrograph Catalog (UCAC2)

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    The second USNO CCD Astrograph Catalog, UCAC2 was released in July 2003. Positions and proper motions for 48,330,571 sources (mostly stars) are available on 3 CDs, supplemented with 2MASS photometry for 99.5% of the sources. The catalog covers the sky area from -90 to +40 degrees declination, going up to +52 in some areas; this completely supersedes the UCAC1 released in 2001. Current epoch positions are obtained from observations with the USNO 8-inch Twin Astrograph equipped with a 4k CCD camera. The precision of the positions are 15 to 70 mas, depending on magnitude, with estimated systematic errors of 10 mas or below. Proper motions are derived by utilizing over 140 ground-and space-based catalogs, including Hipparcos/Tycho, the AC2000.2, as well as yet unpublished re-measures of the AGK2 plates and scans from the NPM and SPM plates. Proper motion errors are about 1 to 3 mas/yr for stars to 12th magnitude, and about 4 to 7 mas/yr for fainter stars to 16th magnitude. The observational data, astrometric reductions, results, and important information for the users of this catalog are presented.Comment: accepted by AJ, AAS LaTeX, 14 figures, 10 table

    The WKB Approximation without Divergences

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    In this paper, the WKB approximation to the scattering problem is developed without the divergences which usually appear at the classical turning points. A detailed procedure of complexification is shown to generate results identical to the usual WKB prescription but without the cumbersome connection formulas.Comment: 13 pages, TeX file, to appear in Int. J. Theor. Phy

    Filter parameter tuning analysis for operational orbit determination support

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    The use of an extended Kalman filter (EKF) for operational orbit determination support is being considered by the Goddard Space Flight Center (GSFC) Flight Dynamics Division (FDD). To support that investigation, analysis was performed to determine how an EKF can be tuned for operational support of a set of earth-orbiting spacecraft. The objectives of this analysis were to design and test a general purpose scheme for filter tuning, evaluate the solution accuracies, and develop practical methods to test the consistency of the EKF solutions in an operational environment. The filter was found to be easily tuned to produce estimates that were consistent, agreed with results from batch estimation, and compared well among the common parameters estimated for several spacecraft. The analysis indicates that there is not a sharply defined 'best' tunable parameter set, especially when considering only the position estimates over the data arc. The comparison of the EKF estimates for the user spacecraft showed that the filter is capable of high-accuracy results and can easily meet the current accuracy requirements for the spacecraft included in the investigation. The conclusion is that the EKF is a viable option for FDD operational support
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