PIN12: IMPLICATIONS OF APPLYING DIFFERENT NATIONAL GUIDELINES ADDRESSING SURGICAL ANTIBIOTIC PROPHYLAXIS: A CROSS SECTIONAL STUDY OF 386 PATIENTS UNDERGOING TOTAL HIP REPLACEMENT SURGERY

Presentation at the 7th annual Forum for Development Cooperation with Indigenous Peoples, which commenced the 5th-6th of October 2006. The Centre for Sámi Studies hosted the conference at the University of Tromsø, Norway. Full conference report available at http://hdl.handle.net/10037/2996</a

Sex-Mediated Response to the Beta-Blocker Landiolol in Sepsis: An Experimental, Randomized Study

OBJECTIVES: To investigate any gender effect of the beta-1 adrenergic blocker, landiolol, on cardiac performance and energy metabolism in septic rats, and to explore the expression of genes and proteins involved in this process. DESIGN: Randomized animal study. SETTING: University research laboratory. SUBJECTS: Male and female Wistar rats. INTERVENTIONS: One hour after cecal ligation and puncture, male and female rats were randomly allocated to the following groups: sham male, cecal ligation and puncture male, cecal ligation and puncture + landiolol male, sham female, cecal ligation and puncture female, and cecal ligation and puncture + landiolol female. Cardiac MRI was carried out 18 hours after cecal ligation and puncture to assess in vivo cardiac function. Ex vivo cardiac function measurement and P magnetic resonance spectroscopy were subsequently performed using an isovolumic isolated heart preparation. Finally, we assessed cardiac gene and protein expression. MEASUREMENTS AND MAIN RESULTS: In males, landiolol increased indexed stroke volume by reversing the indexed end-diastolic volume reduction without affecting left ventricle ejection fraction. In females, landiolol did not increase indexed stroke volume and indexed end-diastolic volume but decreased left ventricle ejection fraction. Landiolol had no effect on ex vivo cardiac function and on high-energy phosphate compounds. The effect of landiolol on the gene expression of natriuretic peptide receptor 3 and on protein expression of phosphorylated-AKT:AKT ratio and endothelial nitric oxide synthase was different in males and females. CONCLUSIONS: Landiolol improved the in vivo cardiac performance of septic male rats while deleterious effects were reported in females. Expression of natriuretic peptide receptor 3, phosphorylated-AKT:AKT, and endothelial nitric oxide synthase are signaling pathways to investigate to better understand the sex differences in sepsis

Préparation et propriétés optiques de couches minces d'arséniure de gallium et de tellurure de cadmium

In order to make solar batteries based on thin layers, we have selected gallium arsenide and cadmium telluride. We have studied their optical and photoelectrical properties : the results obtained form the subject of this study. It is shown that the results agree with those of the solid material for reflexion and transmission factors, while the photoelectric properties of thin layers of cadmium telluride are remarkable.Dans le but de réaliser des héliophiles en couche mince, nous avons choisi comme matériau l'arséniure de gallium et le tellurure de cadmium. Nous avons abordé l'étude de leurs propriétés optiques et photoélectriques les résultats obtenus faisant l'objet de cet exposé. Nous montrons que pour les facteurs de réflexion et de transmission, les résultats concordent avec ceux relatifs au matériau massif, tandis que les propriétés photoélectriques présentées par les couches minces de tellurure de cadmium sont surprenantes

Cardiomyoplasty

peer reviewe

Current problems with implantable cardiac pacemakers

peer reviewe

Surgical Technique for Reinforcement Cardiomyoplasty

The current technique for reinforcement cardiomyoplasty in man is detailed. The authors emphasize the critical points that determine the perfect execution of this operation. This innovative surgical approach to heart failure is continuously evolving and, therefore, may be subject to improvement. The major principles however remain valuable