Identity and ethnicity in /t/ in Glasgow-Pakistani high-school girls

This paper presents an acoustic phonetic analysis of Glasgow Asian syllable-initial /t/, in speech data collected from Pakistani-Muslim girls in a Glasgow high school after a long-term participant observation into their shared and differing social practices. The results show differences in spectral energy and shape according to following phonetic segment, and to membership in two contrasting Communities of Practice, more conservative girls maintaining traditional cultural practices, and more rebellious girls whose behaviour challenges such norms. The findings demonstrate that ethnicity is integrally linked with locally-salient identity, and hence that fine phonetic variation which indexes ethnicity is in fact indexical of local ethnic identity

Generalised CP and A4A_4 Family Symmetry

We perform a comprehensive study of family symmetry models based on $A_4$ combined with the generalised CP symmetry $H_{\rm{CP}}$. We investigate the lepton mixing parameters which can be obtained from the original symmetry $A_4\rtimes H_{\rm{CP}}$ breaking to different remnant symmetries in the neutrino and charged lepton sectors. We find that only one case is phenomenologically viable, namely $G^{\nu}_{\rm{CP}}\cong Z^{S}_2\times H^{\nu}_{\rm{CP}}$ in the neutrino sector and $G^{l}_{\rm{CP}}\cong Z^{T}_3\rtimes H^{l}_{\rm{CP}}$ in the charged lepton sector, leading to the prediction of no CP violation, namely $\delta_{CP}$ and the Majorana phases $\alpha_{21}$ and $\alpha_{31}$ are all equal to either zero or $\pi$. We then propose an effective supersymmetric model based on the symmetry $A_4\rtimes H_{\rm{CP}}$ in which trimaximal lepton mixing is predicted together with either zero CP violation or $\delta_{CP}\simeq\pm \pi/2$ with non-trivial Majorana phases. An ultraviolet completion of the effective model yields a neutrino mass matrix which depends on only three real parameters. As a result of this, all three CP phases and the absolute neutrino mass scale are determined, the atmospheric mixing angle is maximal, and the Dirac CP can either be preserved with $\delta_{CP}=0,\pi$ or maximally broken with $\delta_{CP}=\pm \pi /2$ and sharp predictions for the Majorana phases and neutrinoless double beta decay.Comment: 38 pages, 3 figure

The ACA Advocacy Competencies: A Social Justice Advocacy Framework for Professional School Counselors

The recent endorsement of the advocacy competencies by the American Counseling Association signals their relevance to the school counseling profession. This article outlines the importance of being a social change agent, the value of advocacy in K-12 schools, and how school counselors can use the advocacy competencies as a framework for promoting access and equity for all students. Implications for professional school counselors and school counselor educators in using the advocacy competencies are also addressed

Calcium entry into stereocilia drives adaptation of the mechanoelectrical transducer current of mammalian cochlear hair cells

Mechanotransduction in the auditory and vestibular systems depends on mechanosensitive ion channels in the stereociliary bundles that project from the apical surface of the sensory hair cells. In lower vertebrates, when the mechanoelectrical transducer (MET) channels are opened by movement of the bundle in the excitatory direction, Ca2+ entry through the open MET channels causes adaptation, rapidly reducing their open probability and resetting their operating range. It remains uncertain whether such Ca2+-dependent adaptation is also present in mammalian hair cells. Hair bundles of both outer and inner hair cells from mice were deflected by using sinewave or step mechanical stimuli applied using a piezo-driven fluid jet. We found that when cochlear hair cells were depolarized near the Ca2+ reversal potential or their hair bundles were exposed to the in vivo endolymphatic Ca2+ concentration (40 µM), all manifestations of adaptation, including the rapid decline of the MET current and the reduction of the available resting MET current, were abolished. MET channel adaptation was also reduced or removed when the intracellular Ca2+ buffer 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid (BAPTA) was increased from a concentration of 0.1 to 10 mM. The findings show that MET current adaptation in mouse auditory hair cells is modulated similarly by extracellular Ca2+, intracellular Ca2+ buffering, and membrane potential, by their common effect on intracellular free Ca2+. Hearing and balance depend on the transduction of mechanical stimuli into electrical signals. This process depends on the opening of mechanoelectrical transducer (MET) channels located at the tips of the shorter of pairs of adjacent stereocilia (1), which are specialized microvilli-like structures that form the hair bundles that project from the upper surface of hair cells (2,3). Deflection of hair bundles in the excitatory direction (i.e., toward the taller stereocilia) stretches specialized linkages, the tip-links, present between adjacent stereocilia (3⇓–5), opening the MET channels. In hair cells from lower vertebrates, open MET channels reclose during constant stimuli via an initial fast adaptation mechanism followed by a much slower, myosin-based motor process, both of which are driven by Ca2+ entry through the channel itself (6⇓⇓⇓⇓⇓⇓–13). In mammalian auditory hair cells, MET current adaptation seems to be mainly driven by the fast mechanism (14⇓–16), although the exact process by which it occurs is still largely unknown. The submillisecond speed associated with the adaptation kinetics of the MET channels in rat and mouse cochlear hair cells (17, 18) indicates that Ca2+, to cause adaptation, has to interact directly with a binding site on the channel or via an accessory protein (16). However, a recent investigation on rat auditory hair cells has challenged the view that Ca2+ entry is required for fast adaptation, and instead proposed an as-yet-undefined mechanism involving a Ca2+-independent reduction in the viscoelastic force of elements in series with the MET channels (19). In the present study, we further investigated the role of Ca2+ in MET channel adaptation in mouse cochlear hair cells by deflecting their hair bundles using a piezo-driven fluid jet, which is believed to produce a more uniform deflection of the hair bundles (20⇓⇓–23) compared with the piezo-driven glass rod (19, 24)

Tmc1 point mutation affects Ca2+ sensitivity and block by dihydrostreptomycin of the mechanoelectrical transducer current of mouse outer hair cells

The transduction of sound into electrical signals depends on mechanically sensitive ion channels in the stereociliary bundle. The molecular composition of this mechanoelectrical transducer (MET) channel is not yet known. Transmembrane channel-like protein isoforms 1 (TMC1) and 2 (TMC2) have been proposed to form part of the MET channel, although their exact roles are still unclear. Using Beethoven (Tmc1Bth/Bth) mice, which have an M412K point mutation in TMC1 that adds a positive charge, we found that Ca2+ permeability and conductance of the MET channel of outer hair cells (OHCs) were reduced. Tmc1Bth/Bth OHCs were also less sensitive to block by the permeant MET channel blocker dihydrostreptomycin, whether applied extracellularly or intracellularly. These findings suggest that the amino acid that is mutated in Bth is situated at or near the negatively charged binding site for dihydrostreptomycin within the permeation pore of the channel. We also found that the Ca2+ dependence of the operating range of the MET channel was altered by the M412K mutation. Depolarization did not increase the resting open probability of the MET current of Tmc1Bth/Bth OHCs, whereas raising the intracellular concentration of the Ca2+ chelator BAPTA caused smaller increases in resting open probability in Bth mutant OHCs than in wild-type control cells. We propose that these observations can be explained by the reduced Ca2+ permeability of the mutated MET channel indirectly causing the Ca2+ sensor for adaptation, at or near the intracellular face of the MET channel, to become more sensitive to Ca2+ influx as a compensatory mechanism

The buckling of thin-walled circular cylinders under axial compression and bending

Bucking of thin-walled electroplated copper and Mylar circular cylinders under axial compression and bendin

Responding to accents after experiencing interactive or mediated speech

Very little known is about how speakers learn about and/or respond to speech experienced without the possibility for interaction. This paper reports an experiment which considers the effects of two kinds of exposure to speech (interactive or non-interactive mediated) on Scottish English speakers’ responses to another accent (Southern British English), for two processing tasks, phonological awareness and speech production. Only marginal group effects are found according to exposure type. The main findings show a difference between subjects according to exposure type before exposure, and individual shifts in responses to speech according to exposure type

Extreme Ultraviolet Emission in the Fornax Cluster of Galaxies

We present studies of the Extreme Ultraviolet (EUV) emission in the Fornax cluster of galaxies; a relatively nearby well-studied cluster with X-ray emitting cluster gas and a very large radio source. We examine both the large-scale (~size of the X-ray emitting cluster gas), and the small-scale (<arcmin) emission. We find that this cluster has large-scale diffuse EUV emission. However, at the sensitivity level of the existing EUVE data, this emission is due entirely to the low energy tail of the X-ray emitting gas. We have also examined small-scale structures in raw EUVE images of this cluster. We find that small-scale irregularities are present in all raw Deep Survey images as a result of small-scale detector effects. These effects can be removed by appropriate flat-fielding. After flat-fielding, the Fornax cluster still shows a few significant regions of small-scale EUV enhancement. We find that these are emission from stars and galaxies in the field. We find that at existing levels of sensitivity, there is no excess EUV emission in the cluster on either large or small scales.Comment: 6 pages, 3 eps figures, aastex5, Accepted to ApJ