12 research outputs found
Complications after benign hysterectomy, according to procedure: a population‐based prospective cohort study from the Danish hysterectomy database, 2004–2015
Pentachlorophenol and tetrachlorophenols in wadden sediment and clams Mya arenaria of the Jadebusen after a 14-year period of wastewater discharge containing pentachlorophenol
Thermodynamic Data of Proton Transfer Hydrogen Bonds as a Function of the Properties of the Hydrogen Bond Donors and the Polarity of the Environments
Highly Effective Extraction of Iron(III) with 4-Isopropyltropolone in Nonpolar Solvents Containing 3,5-Dichlorophenol as a Synergist.
The Determination of Pentachlorophenol and Tetrachlorophenols in Wadden Sediment and Clams (Myaarenaria)
A randomized prospective study of single-port and four-port approaches for hysterectomy in terms of postoperative pain
Catalytic activation of pre-substrates via dynamic fragment assembly on protein templates
Dynamic multi-component covalent assembly for the reversible binding of secondary alcohols and chirality sensing
Reversible covalent bonding is often employed for the creation of novel supramolecular structures, multi-component assemblies, and sensing ensembles. In spite of remarkable success of dynamic covalent systems, the reversible binding of a mono-alcohol with high strength is challenging. Here we show that a strategy of carbonyl activation and hemiaminal ether stabilization can be embodied in a four-component reversible assembly that creates a tetradentate ligand and incorporates secondary alcohols with exceptionally high affinity. Evidence is presented that the intermediate leading to binding and exchange of alcohols is an iminium ion. Further, to demonstrate the use of this assembly process we explored chirality sensing and enantiomeric excess determinations. An induced twist in the ligand by a chiral mono-ol results in large Cotton effects in the circular dichroism spectra indicative of the alcohol’s handedness. The strategy revealed in this study should prove broadly applicable for the incorporation of alcohols into supramolecular architecture construction