43 research outputs found

    The concept of mass – gravitic and inertial in eurhythmic physics

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    The concept of mass, be it gravitic or inertial, has played a major role in traditional physics. The meaning of the concept of mass and the equivalence between inertial and gravitic mass have been and are object of great polemics in the arena of scientific discussion. In the nonlinear complex inter-relational Eurhythmic Physics, the concept of mass, that has been assumed as a fundamental idea, no longer shares this attribute. In this way of looking at Nature the concept of mass loses its fundamental status being only a relational and, under certain circumstances, useful concept

    Proposed Experiments to Clarify the Real Nature of the Quantum Waves

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    The nature of quantum waves, whether they are real physical waves or, on the contrary, mere probability waves, has been a very controversial theme since the beginning of quantum theory. Here we present some possible experiments that may clarify the problem.info:eu-repo/semantics/publishedVersio

    Louis de Broglie Realistic Research Program and the experimental detection of Quantum Waves

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    We give a brief historical review of Louis de Broglie realistic research program as developed in Lisbon’s research group about nonlinear quantum physics. We propose and discuss “yes-no” type experiments to physically detect quantum waves, independently of the associated corpuscles. Thus, deciding if they are real physical perturbations or mere probability waves. We finally present a possible technological application for the detection of such waves in quantum communication.info:eu-repo/semantics/publishedVersio

    An Introduction to Eurhythmic Philosophy

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    Eurhythmic Philosophy, also called the Philosophy of Rhythms, aims to extend the concepts of harmony, complexity, cooperative interaction, emergence and non-linearity to several areas of human knowledge. This text is intended to invite readers into participating in what is hoped to become a new philosophical paradigm, i.e. a new intellectual soil fertile in methods and ideas, and believed to be specifically suited to deal with the challenges and problems of the 21st century

    A biphotons double slit experiment

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    In this paper we present a double slit experiment where two undistinguishable photons produced by type I PDC are sent each to a well defined slit. Data about the diffraction and interference patterns for coincidences are presented and discussed. An analysis of these data allows a first test of standard quantum mechanics against de Broglie-Bohm theory

    Serum Metabolomic Signatures Can Predict Subclinical Atherosclerosis in Patients With Systemic Lupus Erythematosus

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    OBJECTIVE: Patients with systemic lupus erythematosus (SLE) have an increased risk of developing cardiovascular disease. Standard serum lipid measurements in clinical practice do not predict cardiovascular disease risk in patients with SLE. More detailed analysis of lipoprotein taxonomy could identify better predictors of cardiovascular disease risk in SLE. Approach and Results: Eighty women with SLE and no history of cardiovascular disease underwent carotid and femoral ultrasound scans; 30 had atherosclerosis plaques (patients with SLE with subclinical plaque) and 50 had no plaques (patients with SLE with no subclinical plaque). Serum samples obtained at the time of the scan were analyzed using a lipoprotein-focused metabolomics platform assessing 228 metabolites by nuclear magnetic resonance spectroscopy. Data were analyzed using logistic regression and 5 binary classification models with 10-fold cross validation. Patients with SLE had global changes in complex lipoprotein profiles compared with healthy controls despite having clinical serum lipid levels within normal ranges. In the SLE cohort, univariate logistic regression identified 4 metabolites associated with subclinical plaque; 3 subclasses of VLDL (very low-density lipoprotein; free cholesterol in medium and large VLDL particles and phospholipids in chylomicrons and extremely large VLDL particles) and leucine. Together with age, these metabolites were also within the top features identified by the lasso logistic regression (with and without interactions) and random forest machine learning models. Logistic regression with interactions differentiated between patients with SLE with subclinical plaque and patients with SLE with no subclinical plaque groups with the greatest accuracy (0.800). Notably, free cholesterol in large VLDL particles and age differentiated between patients with SLE with subclinical plaque and patients with SLE with no subclinical plaque in all models. CONCLUSIONS: Serum metabolites are promising biomarkers to uncover and predict multimetabolic phenotypes of subclinical atherosclerosis in SLE

    A direct kinematical derivation of the relativistic Sagnac effect for light or matter beams

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    The Sagnac time delay and the corresponding Sagnac phase shift, for relativistic matter and electromagnetic beams counter-propagating in a rotating interferometer, are deduced on the ground of relativistic kinematics. This purely kinematical approach allows to explain the ''universality'' of the effect, namely the fact that the Sagnac time difference does not depend on the physical nature of the interfering beams. The only prime requirement is that the counter-propagating beams have the same velocity with respect to any Einstein synchronized local co-moving inertial frame.Comment: 10 pages, 1 EPS figure, to appear in General Relativity and Gravitatio

    The Sagnac Phase Shift suggested by the Aharonov-Bohm effect for relativistic matter beams

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    The phase shift due to the Sagnac Effect, for relativistic matter beams counter-propagating in a rotating interferometer, is deduced on the bases of a a formal analogy with the the Aharonov-Bohm effect. A procedure outlined by Sakurai, in which non relativistic quantum mechanics and newtonian physics appear together with some intrinsically relativistic elements, is generalized to a fully relativistic context, using the Cattaneo's splitting technique. This approach leads to an exact derivation, in a self-consistently relativistic way, of the Sagnac effect. Sakurai's result is recovered in the first order approximation.Comment: 18 pages, LaTeX, 2 EPS figures. To appear in General Relativity and Gravitatio

    Using serum metabolomics analysis to predict sub-clinical atherosclerosis in patients with SLE

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    Background: Patients with systemic lupus erythematosus (SLE) have an increased risk of developing cardiovascular disease (CVD) and 30-40% have sub-clinical atherosclerosis on vascular ultrasound scanning. Standard measurements of serum lipids in clinical practice do not predict CVD risk in patients with SLE. We hypothesise that more detailed analysis of lipoprotein taxonomy could identify better predictors of CVD risk in SLE. / Methods: Eighty patients with SLE and no history of CVD underwent carotid and femoral ultrasound scans; 30 had atherosclerosis plaques (SLE-P) and 50 had no plaques (SLE-NP). Serum samples obtained at the time of the scan were analysed using a lipoprotein-focused metabolomics platform assessing 228 metabolites by nuclear magnetic resonance spectroscopy. Data was analysed using logistic regression and five binary classification models with 10-fold cross validation; decision tree, random forest, support vector machine and lasso (Least Absolute Shrinkage and Selection Operator) logistic regression with and without interactions. / Results: Univariate logistic regression identified four metabolites associated with the presence of sub-clinical plaque; three subclasses of very low density lipoprotein (VLDL) (percentage of free cholesterol in medium and large VLDL particles and percentage of phospholipids in chylomicrons and extremely large VLDL particles) and Leucine. Together with age, these metabolites were also within the top features identified by the lasso logistic regression (with and without interactions) and random forest machine learning models. Logistic regression with interactions differentiated between SLE-P and SLE-NP with greatest accuracy (0.800). Notably, percentage of free cholesterol in large VLDL particles and age were identified by all models as being important to differentiate between SLE-P and SLE-NP patients. / Conclusion: Serum metabolites are a promising biomarker for prediction of sub-clinical atherosclerosis development in SLE patients and could provide novel insight into mechanisms of early atherosclerosis development

    The relativistic Sagnac Effect: two derivations

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    The phase shift due to the Sagnac Effect, for relativistic matter and electromagnetic beams, counter-propagating in a rotating interferometer, is deduced using two different approaches. From one hand, we show that the relativistic law of velocity addition leads to the well known Sagnac time difference, which is the same independently of the physical nature of the interfering beams, evidencing in this way the universality of the effect. Another derivation is based on a formal analogy with the phase shift induced by the magnetic potential for charged particles travelling in a region where a constant vector potential is present: this is the so called Aharonov-Bohm effect. Both derivations are carried out in a fully relativistic context, using a suitable 1+3 splitting that allows us to recognize and define the space where electromagnetic and matter waves propagate: this is an extended 3-space, which we call "relative space". It is recognized as the only space having an actual physical meaning from an operational point of view, and it is identified as the 'physical space of the rotating platform': the geometry of this space turns out to be non Euclidean, according to Einstein's early intuition.Comment: 49 pages, LaTeX, 3 EPS figures. Revised (final) version, minor corrections; to appear in "Relativity in Rotating Frames", ed. G. Rizzi and M.L. Ruggiero, Kluwer Academic Publishers, Dordrecht, (2003). See also http://digilander.libero.it/solciclo
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