Omega meson production in pp collisions with a polarized beam

Model independent formulae are derived for the beam analyzing power $A_y$ and beam to meson spin transfers in $pp \to pp \omega$ taking into consideration all the six threshold partial wave amplitudes covering the $Ss, Sp$ and $Ps$ channels. Attention is also focussed on the empirical determination of the lowest three partial wave amplitudes $f_1, f_2, f_3$ without any discrete ambiguities.Comment: 5 pages, Latex 2

{omega} meson production in pp collisions with a polarized beam

Model independent formulas are derived for the beam analyzing power Ay and beam to meson spin transfers in ppâ ppI, taking into consideration all six threshold partial wave amplitudes f1,...,f6 covering the Ss, Sp, and Ps channels. It is shown that the lowest three partial wave amplitudes f1,f2,f3 can be determined empirically without any discrete ambiguities. Partial information with regard to the amplitudes f4,f5,f6 covering the Ps channel may be extracted, if the measurements are carried through at the double differential level. © 2008 The American Physical Society

Irreducible tensor approach to spin observables in the photoproduction of mesons with arbitrary spin-parity s{sup {pi}}

A theoretical formalism leading to elegant derivation of formulas for all spin observables is outlined for photoproduction of mesons with arbitrary spin-parity sπ. The salient features of this formalism, based on irreducible tensor techniques, are (i) the number of independent irreducible tensor amplitudes is 4(2s+1), (ii) a single compact formula is sufficient to express these amplitudes in terms of allowed electric and magnetic multipole amplitudes, and (iii) all the spin observables, including beam analyzing powers as well as the differential cross section, are expressible in terms of bilinear irreducible tensors of rank 0 to 2(s+1). The relationship between the irreducible tensor amplitudes and the helicity amplitudes is elucidated in general and explicit expressions for the helicity amplitudes are given in terms of the irreducible tensor amplitudes in the particular cases of pseudoscalar and vector meson photoproduction. The connection between the irreducible tensor amplitudes introduced here and the well-known Chew-Goldberger-Low-Nambu amplitudes for photoproduction of pseudoscalar mesons is also established

Empirical Determination of Threshold Partial Wave Amplitudes in pp→ppωp p \to p p \omega

Using the model independent irreducible tensor approach to $\omega$ production in $pp$ collisions, we show theoretically that, it is advantageous to measure experimentally the polarization of $\omega$, in addition to the proposed experimental study employing a polarized beam and a polarized target.Comment: 6 pages, 1 Table, Latex-2

Omega Production in pp Collisions

A model-independent irreducible tensor formalism which has been developed earlier to analyze measurements of $\vec{p}\vec{p}\to pp \pi^\circ$, is extended to present a theoretical discussion of $\vec{p}\vec{p}\to pp \omega$ and the polarization of $\omega$ in $pp\to pp \vec{\omega}$. The recent measurement of unpolarized differential cross section for $pp\to pp \omega$ is analyzed using this theoretical formalism.Comment: 5 pages (double column), no figures, uses revtex

Curcumin-induced inhibition of cellular reactive oxygen species generation: novel therapeutic implications

There is evidence for increased levels of circulating reactive oxygen species (ROS) in diabetics, as indirectly inferred by the findings of increased lipid peroxidation and decreased antioxidant status. Direct measurements of intracellular generation of ROS using fluorescent dyes also demonstrate an association of oxidative stress with diabetes. Although phenolic compounds attenuate oxidative stress-related tissue damage, there are concerns over toxicity of synthetic phenolic antioxidants and this has considerably stimulated interest in investigating the role of natural phenolics in medicinal applications. Curcumin (the primary active principle in turmeric, Curcuma longa Linn.) has been claimed to represent a potential antioxidant and antiinflammatory agent with phytonutrient and bioprotective properties. However there are lack of molecular studies to demonstrate its cellular action and potential molecular targets. In this study the antioxidant effect of curcumin as a function of changes in cellular ROS generation was tested. Our results clearly demonstrate that curcumin abolished both phorbol-12 myristate-13 acetate (PMA) and thapsigargin-induced ROS generation in cells from control and diabetic subjects. The pattern of these ROS inhibitory effects as a function of dose-dependency suggests that curcumin mechanistically interferes with protein kinase C (PKC) and calcium regulation. Simultaneous measurements of ROS and Ca2+ influx suggest that a rise in cytosolic Ca2+ may be a trigger for increased ROS generation. We suggest that the antioxidant and antiangeogenic actions of curcumin, as a mechanism of inhibition of Ca2+ entry and PKC activity, should be further exploited to develop suitable and novel drugs for the treatment of diabetic retinopathy and other diabetic complications

Human Adipose Tissue As A Reservoir For Memory Cd4(+) T Cells And Hiv

Objective: The objective of this study is to determine whether adipose tissue functions as a reservoir for HIV-1. Design: We examined memory CD4(+) T cells and HIV DNA in adipose tissue-stromal vascular fraction (AT-SVF) of five patients [four antiretroviral therapy (ART)-treated and one untreated]. To determine whether adipocytes stimulate CD4(+) T cells and regulate HIV production, primary human adipose cells were cocultured with HIV-infected CD4(+) T cells. Methods: AT-SVF T cells were studied by flow cytometry, and AT-SVF HIV DNA (Gag and Env) was examined by nested PCR and sequence analyses. CD4(+) T-cell activation and HIV production were measured by flow cytometry and ELISA. Results: AT-SVF CD3(+) T cells were activated (\u3e60% CD69(+)) memory CD4(+) and CD8(+) T cells in uninfected and HIV-infected persons, but the AT-SVF CD4(+)/CD8(+) ratio was lower in HIV patients. HIV DNA(Gag and Env) was detected in AT-SVF of all five patients examined by nested PCR, comparably to other tissues [peripheral blood mononuclear cell (PBMC), lymph node or thymus]. In coculture experiments, adipocytes increased CD4(+) T-cell activation and HIV production approximately two to three-fold in synergy with gamma-chain cytokines interleukin (IL)-2, IL7 or IL15. These effects were mitigated by neutralizing antibodies against IL6 and integrin-alpha 1 beta 1. Adipocytes also enhanced T-cell viability. Conclusion: Adipose tissues of ART-treated patients harbour activated memory CD4(+) T cells and HIV DNA. Adipocytes promote CD4(+) T-cell activation and HIV production in concert with intrinsic adipose factors. Adipose tissue may be an important reservoir for HIV. Copyright (C) 2015 Wolters Kluwer Health, Inc. All rights reserved