1,629 research outputs found
Semiclassical transition probabilities by an asymptotic evaluation of the S matrix for elastic and inelastic collisions. Bessel uniform approximation
It has been observed in the past that the usual Airy uniform approximation gives probabilities greater than one, especially for near elastic collisions. By mapping the phase onto −ζ cos y + ky + A rather than (1∕3)y^3 − ζy + A one obtains a uniform approximation involving Bessel functions of the first kind, which approaches unity for the elastic collision. This Bessel uniform approximation is no more complicated than the Airy and also gives good agreement with exact quantum results, even if probabilities are large
Self-starting all-polarization maintaining Yb-fiber laser with a polarization maintaining anomalous dispersion higher-order-mode fiber
A Phase-Field Model of Spiral Dendritic Growth
Domains of condensed-phase monolayers of chiral molecules exhibit a variety
of interesting nonequilibrium structures when formed via pressurization. To
model these domain patterns, we add a complex field describing the tilt degree
of freedom to an (anisotropic) complex-phase-field solidification model. The
resulting formalism allows for the inclusion of (in general, non-reflection
symmetric) interactions between the tilt, the solid-liquid interface, and the
bond orientation. Simulations demonstrate the ability of the model to exhibit
spiral dendritic growth.Comment: text plus Four postscript figure file
Sub-100 fs pulses from an all-polarization maintaining Yb-fiber oscillator with an anomalous dispersion higher-order-mode fiber
Multiple coating thicknesses for sampling of organic pollutants – linear regressions confirm equilibrium even in challenging environmental media
The Shapes of Flux Domains in the Intermediate State of Type-I Superconductors
In the intermediate state of a thin type-I superconductor magnetic flux
penetrates in a disordered set of highly branched and fingered macroscopic
domains. To understand these shapes, we study in detail a recently proposed
"current-loop" (CL) model that models the intermediate state as a collection of
tense current ribbons flowing along the superconducting-normal interfaces and
subject to the constraint of global flux conservation. The validity of this
model is tested through a detailed reanalysis of Landau's original conformal
mapping treatment of the laminar state, in which the superconductor-normal
interfaces are flared within the slab, and of a closely-related straight-lamina
model. A simplified dynamical model is described that elucidates the nature of
possible shape instabilities of flux stripes and stripe arrays, and numerical
studies of the highly nonlinear regime of those instabilities demonstrate
patterns like those seen experimentally. Of particular interest is the buckling
instability commonly seen in the intermediate state. The free-boundary approach
further allows for a calculation of the elastic properties of the laminar
state, which closely resembles that of smectic liquid crystals. We suggest
several new experiments to explore of flux domain shape instabilities,
including an Eckhaus instability induced by changing the out-of-plane magnetic
field, and an analog of the Helfrich-Hurault instability of smectics induced by
an in-plane field.Comment: 23 pages, 22 bitmapped postscript figures, RevTex 3.0, submitted to
Phys. Rev. B. Higher resolution figures may be obtained by contacting the
author
Gel-Based Proteomics of Clinical Samples Identifies Potential Serological Biomarkers for Early Detection of Colorectal Cancer
The burden of colorectal cancer (CRC) is considerable—approximately 1.8 million people are diagnosed each year with CRC and of these about half will succumb to the disease. In the case of CRC, there is strong evidence that an early diagnosis leads to a better prognosis, with metastatic CRC having a 5-year survival that is only slightly greater than 10% compared with up to 90% for stage I CRC. Clearly, biomarkers for the early detection of CRC would have a major clinical impact. We implemented a coherent gel-based proteomics biomarker discovery platform for the identification of clinically useful biomarkers for the early detection of CRC. Potential protein biomarkers were identified by a 2D gel-based analysis of a cohort composed of 128 CRC and site-matched normal tissue biopsies. Potential biomarkers were prioritized and assays to quantitatively measure plasma expression of the candidate biomarkers were developed. Those biomarkers that fulfilled the preset criteria for technical validity were validated in a case-control set of plasma samples, including 70 patients with CRC, adenomas, or non-cancer diseases and healthy individuals in each group. We identified 63 consistently upregulated polypeptides (factor of four-fold or more) in our proteomics analysis. We selected 10 out of these 63 upregulated polypeptides, and established assays to measure the concentration of each one of the ten biomarkers in plasma samples. Biomarker levels were analyzed in plasma samples from healthy individuals, individuals with adenomas, CRC patients, and patients with non-cancer diseases and we identified one protein, tropomyosin 3 (Tpm3) that could discriminate CRC at a significant level (p = 0.0146). Our results suggest that at least one of the identified proteins, Tpm3, could be used as a biomarker in the early detection of CRC, and further studies should provide unequivocal evidence for the real-life clinical validity and usefulness of Tpm3
Signature of Chaotic Diffusion in Band Spectra
We investigate the two-point correlations in the band spectra of spatially
periodic systems that exhibit chaotic diffusion in the classical limit. By
including level pairs pertaining to non-identical quasimomenta, we define form
factors with the winding number as a spatial argument. For times smaller than
the Heisenberg time, they are related to the full space-time dependence of the
classical diffusion propagator. They approach constant asymptotes via a regime,
reflecting quantal ballistic motion, where they decay by a factor proportional
to the number of unit cells. We derive a universal scaling function for the
long-time behaviour. Our results are substantiated by a numerical study of the
kicked rotor on a torus and a quasi-one-dimensional billiard chain.Comment: 8 pages, REVTeX, 5 figures (eps
Prevalence of avascular necrosis in idiopathic inflammatory myositis: a single center experience.
OBJECTIVES: To assess the prevalence of avascular necrosis (AVN) in a large cohort of patients with idiopathic inflammatory myopathies (IIM) and define the major associated risk factors.
METHODS: We retrospectively reviewed the electronic medical records of all patients with a definitive diagnosis of IIM enrolled in our registry between 2003-2017 and followed until 2020. Pertinent demographic, clinical, serologic and imaging data were collected. A matched group of patients without AVN was then selected for comparison.
RESULTS: 1680 patients were diagnosed with IIM. Fifty-one patients developed AVN, with an overall prevalence of 3%. Musculoskeletal magnetic resonance imaging (MSK MRI) was available for 1085 patients and AVN was present in 46 patients (43 lower extremities and 3 upper extremities MRI studies), with a relative prevalence of 4.2%. Most patients with AVN were Caucasian females (57%) with a mean age at diagnosis of 44.5 ± 12.4 years. 61% had dermatomyositis (DM) and 29% had polymyositis (PM). The median time from onset of IIM to diagnosis of AVN was 46 months. The hip joint was most commonly involved in 76% of cases, followed by the knee joint in 15% and shoulder joint in 9%. 81% of patients were asymptomatic. Established risk factors for AVN were not found to be associated with the development of AVN in IIM patients.
CONCLUSION: Although mostly asymptomatic and incidental, the overall prevalence of AVN in IIM was 3% and the prevalence by MRI was 4.2%. None of the established risk factors were found to be associated with AVN development
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