334 research outputs found
A Measurement of the Angular Power Spectrum of the CMB from l = 100 to 400
We report on a measurement of the angular spectrum of the CMB between
and made at 144 GHz from Cerro Toco in the
Chilean altiplano. When the new data are combined with previous data at 30 and
40 GHz, taken with the same instrument observing the same section of sky, we
find: 1) a rise in the angular spectrum to a maximum with K at and a fall at , thereby localizing the peak
near ; and 2) that the anisotropy at has the
spectrum of the CMB.Comment: 4 pages, 2 figures. Revised version; includes Ned Wright's postscript
fix. Accepted by ApJL. Website at http://physics.princeton.edu/~cmb
Intravitreal Administration of Human Bone Marrow CD34+ Stem Cells in a Murine Model of Retinal Degeneration.
PurposeIntravitreal murine lineage-negative bone marrow (BM) hematopoietic cells slow down retinal degeneration. Because human BM CD34+ hematopoietic cells are not precisely comparable to murine cells, this study examined the effect of intravitreal human BM CD34+ cells on the degenerating retina using a murine model.MethodsC3H/HeJrd1/rd1 mice, immunosuppressed systemically with tacrolimus and rapamycin, were injected intravitreally with PBS (n = 16) or CD34+ cells (n = 16) isolated from human BM using a magnetic cell sorter and labeled with enhanced green fluorescent protein (EGFP). After 1 and 4 weeks, the injected eyes were imaged with scanning laser ophthalmoscopy (SLO)/optical coherence tomography (OCT) and tested with electroretinography (ERG). Eyes were harvested after euthanasia for immunohistochemical and microarray analysis of the retina.ResultsIn vivo SLO fundus imaging visualized EGFP-labeled cells within the eyes following intravitreal injection. Simultaneous OCT analysis localized the EGFP-labeled cells on the retinal surface resulting in a saw-toothed appearance. Immunohistochemical analysis of the retina identified EGFP-labeled cells on the retinal surface and adjacent to ganglion cells. Electroretinography testing showed a flat signal both at 1 and 4 weeks following injection in all eyes. Microarray analysis of the retina following cell injection showed altered expression of more than 300 mouse genes, predominantly those regulating photoreceptor function and maintenance and apoptosis.ConclusionsIntravitreal human BM CD34+ cells rapidly home to the degenerating retinal surface. Although a functional benefit of this cell therapy was not seen on ERG in this rapidly progressive retinal degeneration model, molecular changes in the retina associated with CD34+ cell therapy suggest potential trophic regenerative effects that warrant further exploration
Statistical Isotropy violation of the CMB brightness fluctuations
Certain anomalies at large angular scales in the cosmic microwave background
measured by WMAP have been suggested as possible evidence of breakdown of
statistical isotropy(SI). Most CMB photons free-stream to the present from the
surface of last scattering. It is thus reasonable to expect statistical
isotropy violation in the CMB photon distribution observed now to have
originated from SI violation in the baryon-photon fluid at last scattering, in
addition to anisotropy of the primordial power spectrum studied earlier in
literature.
We consider the generalized anisotropic brightness distribution fluctuations,
(at conformal time ) in contrast to the
SI case where it is simply a function of and . The brightness fluctuations expanded in Bipolar Spherical Harmonic
(BipoSH) series, can then be written as where terms encode deviations from statistical isotropy. We
study the evolution of from
non-zero terms at last
scattering. Similar to the SI case, power at small spherical harmonic (SH)
multipoles of at the last
scattering, is transferred to at
larger SH multipoles. The structural similarity is more apparent in the
asymptotic expression for large values of the final SH multipoles. This
formalism allows an elegant identification of any SI violation observed today
to a possible origin in the SI violation present in the baryon-photon fluid
(eg., due to the presence of significant magnetic field).Comment: 14 pages, 4 figures, added illustrative example of SI violation in
baryon-photon fluid, matches version accepted for publication in Phys. Rev.
Modulation of CMB polarization with a warm rapidly-rotating half-wave plate on the Atacama B-Mode Search (ABS) instrument
We evaluate the modulation of Cosmic Microwave Background (CMB) polarization
using a rapidly-rotating, half-wave plate (HWP) on the Atacama B-Mode Search
(ABS). After demodulating the time-ordered-data (TOD), we find a significant
reduction of atmospheric fluctuations. The demodulated TOD is stable on time
scales of 500-1000 seconds, corresponding to frequencies of 1-2 mHz. This
facilitates recovery of cosmological information at large angular scales, which
are typically available only from balloon-borne or satellite experiments. This
technique also achieves a sensitive measurement of celestial polarization
without differencing the TOD of paired detectors sensitive to two orthogonal
linear polarizations. This is the first demonstration of the ability to remove
atmospheric contamination at these levels from a ground-based platform using a
rapidly-rotating HWP.Comment: 8 pages, 8 figures, Published in RSI under the title "Modulation of
cosmic microwave background polarization with a warm rapidly rotating
half-wave plate on the Atacama B-Mode Search instrument.
Cosmological constraints on neutrino plus axion hot dark matter: Update after WMAP-5
We update our previous constraints on two-component hot dark matter (axions
and neutrinos), including the recent WMAP 5-year data release. Marginalising
over sum m_nu provides m_a < 1.02 eV (95% C.L.) for the axion mass. In the
absence of axions we find sum m_nu < 0.63 eV (95% C.L.).Comment: 4 pages, 1 figure, uses iopart.cls; v2 matches published versio
Five-Year Wilkinson Microwave Anisotropy Probe (WMAP) Observations: Bayesian Estimation of CMB Polarization Maps
We describe a sampling method to estimate the polarized CMB signal from
observed maps of the sky. We use a Metropolis-within-Gibbs algorithm to
estimate the polarized CMB map, containing Q and U Stokes parameters at each
pixel, and its covariance matrix. These can be used as inputs for cosmological
analyses. The polarized sky signal is parameterized as the sum of three
components: CMB, synchrotron emission, and thermal dust emission. The polarized
Galactic components are modeled with spatially varying power law spectral
indices for the synchrotron, and a fixed power law for the dust, and their
component maps are estimated as by-products. We apply the method to simulated
low resolution maps with pixels of side 7.2 degrees, using diagonal and full
noise realizations drawn from the WMAP noise matrices. The CMB maps are
recovered with goodness of fit consistent with errors. Computing the likelihood
of the E-mode power in the maps as a function of optical depth to reionization,
tau, for fixed temperature anisotropy power, we recover tau=0.091+-0.019 for a
simulation with input tau=0.1, and mean tau=0.098 averaged over 10 simulations.
A `null' simulation with no polarized CMB signal has maximum likelihood
consistent with tau=0. The method is applied to the five-year WMAP data, using
the K, Ka, Q and V channels. We find tau=0.090+-0.019, compared to
tau=0.086+-0.016 from the template-cleaned maps used in the primary WMAP
analysis. The synchrotron spectral index, beta, averaged over high
signal-to-noise pixels with standard deviation sigma(beta)<0.25, but excluding
~6% of the sky masked in the Galactic plane, is -3.03+-0.04. This estimate does
not vary significantly with Galactic latitude, although includes an informative
prior.Comment: 11 pages, 9 figures, matches version accepted by Ap
Probing the last scattering surface through the recent and future CMB observations
We have constrained the extended (delayed and accelerated) models of hydrogen
recombination, by investigating associated changes of the position and the
width of the last scattering surface. Using the recent CMB and SDSS data, we
find that the recent data constraints favor the accelerated recombination
model, though the other models (standard, delayed recombination) are not ruled
out at 1- confidence level. If the accelerated recombination had
actually occurred in our early Universe, baryonic clustering on small-scales is
likely to be the cause of it. By comparing the ionization history of baryonic
cloud models with that of the best-fit accelerated recombination model, we find
that some portion of our early Universe has baryonic underdensity. We have made
the forecast on the PLANCK data constraint, which shows that we will be able to
rule out the standard or delayed recombination models, if the recombination in
our early Universe had proceeded with or lower, and
residual foregrounds and systematic effects are negligible.Comment: v2: matched with the accepted version (conclusions unchanged
Three-Year Wilkinson Microwave Anisotropy Probe (WMAP) Observations: Foreground Polarization
We present a full-sky model of polarized Galactic microwave emission based on
three years of observations by the Wilkinson Microwave Anisotropy Probe (WMAP)
at frequencies from 23 to 94 GHz. The model compares maps of the Stokes Q and U
components from each of the 5 WMAP frequency bands in order to separate
synchrotron from dust emission, taking into account the spatial and frequency
dependence of the synchrotron and dust components. This simple two-component
model of the interstellar medium accounts for at least 97% of the polarized
emission in the WMAP maps of the microwave sky. Synchrotron emission dominates
the polarized foregrounds at frequencies below 50 GHz, and is comparable to the
dust contribution at 65 GHz. The spectral index of the synchrotron component,
derived solely from polarization data, is -3.2 averaged over the full sky, with
a modestly flatter index on the Galactic plane. The synchrotron emission has
mean polarization fraction 2--4% in the Galactic plane and rising to over 20%
at high latitude, with prominent features such as the North Galactic Spur more
polarized than the diffuse component. Thermal dust emission has polarization
fraction 1% near the Galactic center, rising to 6% at the anti-center. Diffuse
emission from high-latitude dust is also polarized with mean fractional
polarization 0.036 +/- 0.011.Comment: 9 pages with 8 figures. For higher quality figures, see the version
posted at http://lambda.gsfc.nasa.gov/product/map/dr2/map_bibliography.cf
The Atacama Cosmology Telescope: Physical Properties of Sunyaev-Zel'dovich Effect Clusters on the Celestial Equator
We present the optical and X-ray properties of 68 galaxy clusters selected
via the Sunyaev-Zel'dovich Effect at 148 GHz by the Atacama Cosmology Telescope
(ACT). Our sample, from an area of 504 square degrees centered on the celestial
equator, is divided into two regions. The main region uses 270 square degrees
of the ACT survey that overlaps with the co-added ugriz imaging from the Sloan
Digital Sky Survey (SDSS) over Stripe 82 plus additional near-infrared pointed
observations with the Apache Point Observatory 3.5-meter telescope. We confirm
a total of 49 clusters to z~1.3, of which 22 (all at z>0.55) are new
discoveries. For the second region the regular-depth SDSS imaging allows us to
confirm 19 more clusters up to z~0.7, of which 10 systems are new. We present
the optical richness, photometric redshifts, and separation between the SZ
position and the brightest cluster galaxy (BCG). We find no significant offset
between the cluster SZ centroid and BCG location and a weak correlation between
optical richness and SZ-derived mass. We also present X-ray fluxes and
luminosities from the ROSAT All Sky Survey which confirm that this is a massive
sample. One of the newly discovered clusters, ACT-CL J0044.4+0113 at z=1.1
(photometric), has an integrated XMM-Newton X-ray temperature of kT_x=7.9+/-1.0
keV and combined mass of M_200a=8.2(-2.5,+3.3)x10^14 M_sun/h70 placing it among
the most massive and X-ray-hot clusters known at redshifts beyond z=1. We also
highlight the optically-rich cluster ACT-CL J2327.4-0204 (RCS2 2327) at z=0.705
(spectroscopic) as the most significant detection of the whole equatorial
sample with a Chandra-derived mass of M_200a=1.9(-0.4,+0.6)x10^15 M_sun/h70,
comparable to some of the most massive known clusters like "El Gordo" and the
Bullet Cluster.Comment: 18 pages, 12 figures. Accepted to the Astrophysical Journal. New
version includes minor changes in the accepted pape
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