Letter from J. R. Winder to Barney Colson

Letter from J. R. Winder to Barney (B. R.) Colson. The one-page handwritten letter is dated 14 September 1912. There is a transcript of the correspondence included in the item PDF

Letter from J. R. Minder to B. R. Colson

Letter from J. R. Minder to B. R. Colson. The one-page handwritten correspondence is on Christian Word and Work letterhead and is dated 22 July 1912. A transcription of the letter is included in the item PDF

Outcomes in Living Liver Donor “Heroes” After the Spotlight Fades

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/149256/1/lt25459_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/149256/2/lt25459.pd

The synthesis and biological evaluation of a kabiramide C fragment modified with a WH2 consensus actin-binding motif as a potential disruptor of the actin cytoskeleton

Despite its low affinity for actin monomers, a fragment of kabiramide C disrupts actin filamentsin vitroand in cells.</p

Dystrophin and utrophin: the missing links!

AbstractThere is considerable sequence homology between dystrophin and utrophin, both at the protein and DNA level, and consequently it was assumed that their domain structures and functions would be similar. As more of the detailed biochemical and cell biological properties of these two proteins become known, so it becomes clear that there are subtle if not significant differences between them. We review recent findings and present new hypotheses into the structural and functional properties of the actin-binding domain, central coiled-coil region and regulatory/membrane protein-binding regions of dystrophin and utrophin

Ocean acidification reduces transfer of essential biomolecules in a natural plankton community

Ocean acidification (OA), a process of increasing seawater acidity caused by the uptake of anthropogenic carbon dioxide (CO 2) by the ocean, is expected to change surface ocean pH to levels unprecedented for millions of years, affecting marine food web structures and trophic interactions. Using an in situ mesocosm approach we investigated effects of OA on community composition and trophic transfer of essential fatty acids (FA) in a natural plankton assemblage. Elevated pCO 2 favored the smallest phytoplankton size class in terms of biomass, primarily picoeukaryotes, at the expense of chlorophyta and haptophyta in the nano-plankton size range. This shift in community composition and size structure was accompanied by a decline in the proportion of polyunsaturated FA (PUFA) to total FA content in the nano- and picophytoplankton size fractions. This decline was mirrored in a continuing reduction in the relative PUFA content of the dominant copepod, Calanus finmarchicus, which primarily fed on the nano-size class. Our results demonstrate that a shift in phytoplankton community composition and biochemical composition in response to rising CO 2 can affect the transfer of essential compounds to higher trophic levels, which rely on their prey as a source for essential macromolecules

Implementation of a patient satisfaction survey in the Pacific University Family Vision Center

Patient satisfaction surveys are a key outcome indicator of quality healthcare delivery. One of the goals in optometric educational systems is to teach interns to provide quality healthcare. The purpose of this study was to design, implement and evaluate a patient satisfaction survey in the Pacific University Family Vision Center. The survey would specifically benefit the intern by measuring and providing valuable feedback in regards to the individual intern\u27s efficiency, professionalism, courtesy and communication skills. The card was also designed to be short, straightforward, and easy to fill out. The results showed a 46% return rate, with a majority of the responses indicating a high level of patient satisfaction. Future implementation of the patient satisfaction survey is recommended in the clinics