246 research outputs found
The Expanding Role of the Counselor as a Vocational Expert Witness
An article written by William J. Weikel and published in the April 1986 Journal of Counseling & Development, pages 523-524
A Multimodal Approach in Dealing with Chronic Epstein-Barr Viral Syndrome
An article written by William J. Weikel and published in the May 1989 Journal of Counseling & Development, pages 522-524
A Survey of Counselors in Private Practice
A survey of members in the American Mental Health Counselors Association conducted to assess certain demographic data and counselor participation in private practice conducted in 1980 by William J. Weikel, Richard W. Daniel and Janet Anderson
The American Mental Health Counselors Association
An article written by William J. Weikel and published in the March 1985 Journal of Counseling & Development, pages 457-460
Millimeter and submillimeter wave technology developments for the next generation of fusion devices
There is increasing demand for compact watt-level coherent sources in the millimeter and submillimeter wave region. The approach that we have taken to satisfy this need is to fabricate two-dimensional grids loaded with oscillators, electronic beam steerers, and frequency multipliers for quasioptical coherent spatial combining of the outputs of a large number of low-power devices
Comparison of the Ki-67 score and S-phase fraction as prognostic variables in soft-tissue sarcoma
Immunohistochemically determined Ki-67 scores and flow cytometrically determined S-phase fractions were successfully evaluated from the primary tumours of 123 patients with soft-tissue sarcoma. All patients had either limb or superficial trunk tumours. Ki-67 score correlated strongly with ploidy, S-phase fraction and grade. Ki-67 did not correlate with the size of the primary tumour. When analysed as a continuous variable, Ki-67 was a stronger predictor of both metastasis-free survival and disease-specific overall survival (P= 0.003 and 0.04 respectively) than was the S-phase fraction (P= 0.06 and 0.07 respectively). We tested the relevance of different cut-point values by dividing the whole material into two parts at every 10% (e.g. 10% of patients vs. the remaining 90%, 20% vs. 80%, etc.). We counted the relative risk and confidence interval at all these cut-off points. Ki-67 had good prognostic discriminating power irrespective of the cut-point value, but S-phase fraction lost its prognostic power at higher cut-point values. In conclusion, we found that Ki-67 is a useful prognostic tool in the treatment of soft-tissue sarcoma patients irrespective of the cut-point value. S-phase fraction can be used at lower cut-point values. © 1999 Cancer Research Campaig
Current Approaches to the Management of Sentinel Node Procedures in Early Vulvar Cancer in Germany : A Web-Based Nationwide Analysis of Practices
Background: Lymph node involvement is the most important prognostic factor for recurrence and survival in vulvar cancer. Sentinel node (SN) procedure can be offered in well-selected
patients with early vulvar cancer. This study aimed to assess current management practices with
respect to the sentinel node procedure in women with early vulvar cancer in Germany. Methods: A
Web-based survey was conducted. Questionnaires were e-mailed to 612 gynecology departments.
Data were summarized as frequencies and analyzed using the chi-square test. Results: A total of
222 hospitals (36.27%) responded to the invitation to participate. Among the responders, 9.5% did
not offer the SN procedure. However, 79.5% evaluated SNs by ultrastaging. In vulvar cancer of the
midline with unilateral localized positive SN, 49.1% and 48.6% of respondents, respectively, would
perform ipsilateral or bilateral inguinal lymph node dissection. Repeat SN procedure was performed
by 16.2% of respondents. For isolated tumor cells (ITCs) or micrometastases, 28.1% and 60.5% of
respondents, respectively, would perform inguinal lymph node dissection, whereas 19.3% and 23.8%,
respectively, would opt for radiation without further surgical intervention. Notably, 50.9% of respondents would not initiate any further therapy and 15.1% would opt for expectant management.
Conclusions: The majority of German hospitals implement the SN procedure. However, only 79.5%
of respondents performed ultrastaging and only 28.1% were aware that ITC may affect survival in
vulvar cancer. There is a need to ensure that the management of vulvar cancer follows the latest
recommendations and clinical evidence. Deviations from state-of-the-art management should only
be after a detailed discussion with the concerned patient
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