1,795 research outputs found
Analysis of Three-Dimensional Protein Images
A fundamental goal of research in molecular biology is to understand protein
structure. Protein crystallography is currently the most successful method for
determining the three-dimensional (3D) conformation of a protein, yet it
remains labor intensive and relies on an expert's ability to derive and
evaluate a protein scene model. In this paper, the problem of protein structure
determination is formulated as an exercise in scene analysis. A computational
methodology is presented in which a 3D image of a protein is segmented into a
graph of critical points. Bayesian and certainty factor approaches are
described and used to analyze critical point graphs and identify meaningful
substructures, such as alpha-helices and beta-sheets. Results of applying the
methodologies to protein images at low and medium resolution are reported. The
research is related to approaches to representation, segmentation and
classification in vision, as well as to top-down approaches to protein
structure prediction.Comment: See http://www.jair.org/ for any accompanying file
Changes in catch rates and length and age at maturity, but not growth, of an estuarine plotosid (Cnidoglanis macrocephalus) after heavy fishing
The hypothesis that heavy fishing pressure has led to changes in the biological characteristics of the estuary cobbler (Cnidoglanis macrocephalus) was tested in a large seasonally open estuary in southwestern Australia, where this species completes its life cycle and is the most
valuable commercial fish species. Comparisons were made between seasonal data collected for this plotosid
(eeltail catfish) in Wilson Inlet during 2005–08 and those recorded with the same fishery-independent sampling regime during 1987–89. These comparisons show that the proportions of larger and older individuals and the catch rates in the
more recent period were far lower, i.e., they constituted reductions of 40% for fish ≥430 mm total length, 62% for fish ≥4 years of age, and 80% for catch rate. In addition, total mortality and fishing-induced mortality estimates increased by factors of ~2 and 2.5, respectively. The indications that the abundance and proportion of older C. macrocephalus declined between the two periods are consistent with the perception of long-term commercial fishermen and their shift toward using a smaller maximum gill net mesh to target this species. The sustained heavy fishing pressure on C. macrocephalus between 1987–89 and 2005–08 was accompanied by a marked reduction in length and age at maturity of this species. The shift in probabilistic maturation reaction norms toward smaller fish in 2005–08
and the lack of a conspicuous change in growth between the two periods indicate that the maturity changes were related to fishery-induced evolution rather than to compensatory
responses to reduced fish densities
Sur l'activité anti-brucellique du Fébyxane
Jacquet Jean, Steeg L. Sur l'activité anti-brucellique du Febyxane. In: Bulletin de l'Académie Vétérinaire de France tome 112 n°4, 1959. pp. 217-224
Local Quantum Measurement and No-Signaling Imply Quantum Correlations
We show that, assuming that quantum mechanics holds locally, the finite speed
of information is the principle that limits all possible correlations between
distant parties to be quantum mechanical as well. Local quantum mechanics means
that a Hilbert space is assigned to each party, and then all local
positive-operator-valued measurements are (in principle) available; however,
the joint system is not necessarily described by a Hilbert space. In
particular, we do not assume the tensor product formalism between the joint
systems. Our result shows that if any experiment would give nonlocal
correlations beyond quantum mechanics, quantum theory would be invalidated even
locally.Comment: Published version. 5 pages, 1 figure
- …