236 research outputs found
Single-cut osteotomy for correction of a complex multiplanar deformity of the radius in a Shetland pony foal
Objective
To describe the surgical correction of a multiplanar deformity of the radius in a pony using a single-cut osteotomy.
Study design
Case report.
Animals
A 9-week-old male Shetland pony foal with a bodyweight of 47âkg.
Methods
The foal presented with a complex multiplanar deformity of the right radius. A 3-dimensional model of the bone was created based on computed tomography (CT) imaging. To correct the deformity, the cutting plane for a single-cut osteotomy was calculated following the mathematical approach described by Sangeorzan et al. After osteotomy, the bone was realigned and stabilized with two 4.5 locking compression plates (LCPs).
Results
Recovery from surgery was uneventful, and the foal remained comfortable. A CT exam 15âweeks after surgery revealed that diaphyseal deformities improved substantially in procurvatum (from 8° to 1°), varus (from 27° to 0°), and rotation (30° to 5°). The operated radius was 2.1 cm shorter than the left. Eighteen-month follow up confirmed a functionally and cosmetically acceptable outcome.
Conclusion
The single-cut osteotomy resulted in the successful correction of a multiplanar equine long-bone deformity with a favorable outcome in a Shetland pony.
Clinical significance
Single-cut osteotomy is an alternative surgical technique for the correction of complex diaphyseal long-bone equine deformities. Computed tomography data and the possibility of printing 3D models provides a significant advantage for rehearsing the procedure and for evaluating the correction that was achieved
The Nature of Aesthetics: How Consumer Culture has Changed our National Parks
Tourism is essentially a modern Western social and cultural phenomenon, the analysis of which has evolved from premodernism through to postmodernism. Tourism differs significantly from nonWestern and historical forms of travel, being closely related to the emergence of modernity with the emphasis on economic viability and consumer culture. The massive growth of tourism over the 20th century and the emergence of a multibillion dollar global tourist industry have impacted on national parks as tourists increasingly seek nature-based experiences. This has occurred in conjunction with increases in leisure time, disposable income, technological improvements in communication and transportation, demographic changes, and a shift in the axis of personal identity and meaningful social action from production to consumption. This article examines how aesthetics fits into this evolution and the current role of national parks with a focus on the emergence of their production through the mass media to a consumer market. Finally, we propose more reflexivity in regards to tourism and place image production
How genealogies are affected by the speed of evolution
In a series of recent works it has been shown that a class of simple models
of evolving populations under selection leads to genealogical trees whose
statistics are given by the Bolthausen-Sznitman coalescent rather than by the
well known Kingman coalescent in the case of neutral evolution. Here we show
that when conditioning the genealogies on the speed of evolution, one finds a
one parameter family of tree statistics which interpolates between the
Bolthausen-Sznitman and Kingman's coalescents. This interpolation can be
calculated explicitly for one specific version of the model, the exponential
model. Numerical simulations of another version of the model and a
phenomenological theory indicate that this one-parameter family of tree
statistics could be universal. We compare this tree structure with those
appearing in other contexts, in particular in the mean field theory of spin
glasses
Survival of near-critical branching Brownian motion
Consider a system of particles performing branching Brownian motion with
negative drift and killed upon hitting zero.
Initially there is one particle at . Kesten showed that the process
survives with positive probability if and only if . Here we are
interested in the asymptotics as \eps\to 0 of the survival probability
. It is proved that if then for all , exists and is a
travelling wave solution of the Fisher-KPP equation. Furthermore, we obtain
sharp asymptotics of the survival probability when and .
The proofs rely on probabilistic methods developed by the authors in a previous
work. This completes earlier work by Harris, Harris and Kyprianou and confirms
predictions made by Derrida and Simon, which were obtained using nonrigorous
PDE methods
Effect of selection on ancestry: an exactly soluble case and its phenomenological generalization
We consider a family of models describing the evolution under selection of a
population whose dynamics can be related to the propagation of noisy traveling
waves. For one particular model, that we shall call the exponential model, the
properties of the traveling wave front can be calculated exactly, as well as
the statistics of the genealogy of the population. One striking result is that,
for this particular model, the genealogical trees have the same statistics as
the trees of replicas in the Parisi mean-field theory of spin glasses. We also
find that in the exponential model, the coalescence times along these trees
grow like the logarithm of the population size. A phenomenological picture of
the propagation of wave fronts that we introduced in a previous work, as well
as our numerical data, suggest that these statistics remain valid for a larger
class of models, while the coalescence times grow like the cube of the
logarithm of the population size.Comment: 26 page
Linking gene expression in the intestine to production of gametes through the phosphate transporter PITR-1 in Caenorhabditis elegans
Inorganic phosphate is an essential mineral for both prokaryotic and eukaryotic cell metabolism and structure. Its uptake into the cell is mediated by membrane bound transporters and coupled to Na+ transport. Mammalian sodium-dependent Pi co-transporters have been grouped into three families NaPi-I, NaPi-II, and NaPi-III. Despite being discovered more than 2 decades ago, very little is known about requirements for NaPi-III transporters in vivo, in the context of intact animal models. Here we find that impaired function of the C. elegans NaPi-III transporter, pitr-1, results in decreased brood size and dramatically increased expression of vitellogenin by the worm intestine. Unexpectedly, we found that the effects of pitr-1 mutation on vitellogenin expression in the intestine could only be rescued by expression of pitr-1 in the germline, and not by expression of pitr-1 in the intestine itself. Our results indicate the existence of a signal from the germline that regulates gene expression in the intestine, perhaps linking nutrient export from the intestine to production of gametes by the germline
Evolution of the most recent common ancestor of a population with no selection
We consider the evolution of a population of fixed size with no selection.
The number of generations to reach the first common ancestor evolves in
time. This evolution can be described by a simple Markov process which allows
one to calculate several characteristics of the time dependence of . We also
study how is correlated to the genetic diversity.Comment: 21 pages, 10 figures, uses RevTex4 and feynmf.sty Corrections :
introduction and conclusion rewritten, references adde
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