Public perceptions of recycled water: a survey of visitors to the London 2012 Olympic Park

The Old Ford Water Recycling Plant, operated by Thames Water, was used to supply non-potable recycled blackwater to some of the venues at the London 2012 Games. In an effort to learn from this experience, Thames Water commissioned a survey of visitors to the Olympic Park during the Games to explore public responses to the water recycling project. Results show a very high level of support for using non-potable recycled blackwater, both in public venues and in homes. Such findings may indicate a growing receptivity towards this technology, and show that Thames Water (and other private water companies) are well placed to encourage and even lead public discussion around the role of water reuse in the future of urban water supplies

Lanthanide(III) complexes of rhodamine-DO3A conjugates as agents for dual-modal imaging

Two novel dual-modal MRI/optical probes based on a rhodamine-DO3A conjugate have been prepared. The bis aqua-Gd(III) complex Gd.L1 and mono aqua-Gd(III) complex Gd.L2 behave as dual-modal imaging probes (r1 = 8.5 and 3.8 mM-1s-1 for Gd.L1 and Gd.L2 respectively; λex = 560 nm and λem = 580 nm for both complexes). The rhodamine fragment is pH sensitive and upon lowering of pH an increase in fluorescence intensity is observed as the spirolactam ring opens to give the highly fluorescent form of the molecule. The ligands are bimodal when coordinated to Tb(III) ions, inducing fluorescence from both the lanthanide center and the rhodamine fluorophore, on two independent time-frames. Confocal imaging experiments were carried out to establish the localization of Gd.L2 in HEK cells. Co-localisation with MitoTracker® Green confirmed that Gd.L2 compartmentalizes in the mitochondria. Gd.L2 was also evaluated as an MRI probe for imaging tumors in BALB/c nude mice bearing M21 xenografts. A 36.5% decrease in T1 within the tumor was observed 30 minutes post injection showing that Gd.L2 is preferentially up taken in the tumor. Gd.L2 is the first small molecule MR/fluorescent dual-modal imaging agent to display an off-on pH switch upon its preferential uptake within the more acidic micro-environment of tumor cells

Mentoring And Social Capital: Learning And Perceived Networking Opportunities For Women In Central Pennsylvania Rotary Clubs

This paper explores learning in Rotary clubs that have newly allowed women as members. The main focus of the paper is women’s perception of learning within the confines of these clubs with respect to mentoring and social capital’s existence. The study explores gaps in power within a middle-class Pennsylvania society. This study used phenomenology and grounded theory to investigate the lived experiences of women that are members of Rotary clubs in central Pennsylvania

Multi-physics ensemble snow modelling in the western Himalaya

Combining multiple data sources with multi-physics simulation frameworks offers new potential to extend snow model inter-comparison efforts to the Himalaya. As such, this study evaluates the sensitivity of simulated regional snow cover and runoff dynamics to different snowpack process representations. The evaluation is based on a spatially distributed version of the Factorial Snowpack Model (FSM) set up for the Astore catchment in the upper Indus basin. The FSM multi-physics model was driven by climate fields from the High Asia Refined Analysis (HAR) dynamical downscaling product. Ensemble performance was evaluated primarily using MODIS remote sensing of snow-covered area, albedo and land surface temperature. In line with previous snow model inter-comparisons, no single FSM configuration performs best in all of the years simulated. However, the results demonstrate that performance variation in this case is at least partly related to inaccuracies in the sequencing of inter-annual variation in HAR climate inputs, not just FSM model limitations. Ensemble spread is dominated by interactions between parameterisations of albedo, snowpack hydrology and atmospheric stability effects on turbulent heat fluxes. The resulting ensemble structure is similar in different years, which leads to systematic divergence in ablation and mass balance at high elevations. While ensemble spread and errors are notably lower when viewed as anomalies, FSM configurations show important differences in their absolute sensitivity to climate variation. Comparison with observations suggests that a subset of the ensemble should be retained for climate change projections, namely those members including prognostic albedo and liquid water retention, refreezing and drainage processes

Experimental calibration of hornblende as a proposed emprical geobarometer

The recent Eos report by Anderson [1987] reviewed prospects for using dated granitoid plutons as crustal nails in the reconstruction of descent or ascent of deformed crust during orogenic processes, if suitable geobarometers could be established. Hammarstrom and Zen [1986] and Hollister et al [1987] have proposed an empirical geobarometer for calcalkaline plutonic rocks of tonalite and granodiorite composition based on the total Al content (Air) of calcic hornblendes. This proposition has generated considerable interest

Knowledge transfer and exchange: a look at the literature in relation to research and policy

Within the field of health policy, there have been widespread calls for the increased or improved use of evidence within policy making. This reflects an ambition to deliver better policy in terms of outcomes, resource efficiency and effectiveness, and a belief that this can be achieved through utilising the available evidence to inform and guide decision making. For those tasked with improving the uptake of a piece or body of evidence, for policy makers aiming to improve their evidence use, or for researches investigating this question, a number of conceptual questions remain on how to actually achieve this, such as: What should count as evidence for policy making? Who should govern (or steer) the use of research evidence for policy? What is ‘good evidence’ for decision making? What is the ‘good use’ of evidence from a governance perspective? How is research knowledge typically translated into policy? How can one ‘improve’ the use or uptake of evidence in policy making? The GRIP-Health Project is a 5 year, European Research Council supported programme of work that aims to improve the use of research evidence in health policy through undertaking research on the political aspects of health policy making and evidence use. The project has developed a number of working papers that engage with some of these topics.1 This current paper is concerned with the last two of the questions listed above, specifically reviewing key aspects of Knowledge Transfer and Exchange (KTE) related to getting research into policy and practice. While the health sector is increasingly motivated by a desire to get research evidence into policy, outside the field of health there is a much broader body of work that is specifically concerned with how evidence and knowledge are transferred, translated, or taken up by different policy actors. Various theories attempt to establish how KTE works, the contextual factors that influence the process, and how to achieve maximum impact for relevant bodies of evidence. Acronyms and terminology used in this field vary accordingly, and can include knowledge transfer, knowledge translation, knowledge management, and knowledge brokering. These various terms have been grouped together under the rubric ‘K*’ by some authors to reflect the multiple overlapping terms 2 Prior working papers in this series deal with aspects of: Stewardship of health evidence; hierarches and appropriateness of evidence; and institutional approaches to evidence uptake research. Working papers and other outputs of the programme are available at the GRIP-Health website http://www.lshtm.ac.uk/groups/griphealth/resources/index.html 3 (c.f. Shaxson et al., 2012). However, in this paper, we use the term KTE to refer to the general body of literature focused on issues of knowledge production, dissemination, uptake and use in policymaking. As the body of work on KTE is extensive, it was decided not to attempt a complete or systematic review of the literature. There are, however, several papers which attempt to synthesise the existing literature or systematically review elements of the KTE field. These reviews provide a starting point for mapping the field to help inform efforts to improve the use of research evidence in policy. The current paper therefore has two objectives. First, it summarises and synthesises a set of identified KTE review papers in order to undertake a comparison of their similarities and their differences on the main areas they cover, to provide a basic mapping of key KTE concepts. After this, it then explores some key themes that emerge from the KTE literature which are of particular relevance to the GRIP-Health programme and other researchers or stakeholders who are tasked with improving evidence uptake

Stability of hexagonal solidification patterns

We investigate the dynamics of cellular solidification patterns using three-dimensional phase-field simulations. The cells can organize into stable hexagonal patterns or exhibit unsteady evolutions. We identify the relevant secondary instabilities of regular hexagonal arrays and find that the stability boundaries depend significantly on the strength of crystalline anisotropy. We also find multiplet states that can be reached by applying well-defined perturbations to a pre-existing hexagonal array.Comment: Minor changes, mainly in introduction and conclusion, one reference adde

Poor attention rather than hyperactivity/impulsivity predicts academic achievement in very preterm and full-term adolescents

Background: Very preterm (VP) children are at particular risk for attention deficit/hyperactivity disorder (ADHD) of the inattentive subtype. It is unknown whether the neurodevelopmental pathways to academic underachievement are the same as in the general population. This study investigated whether middle childhood attention or hyperactivity/impulsivity problems are better predictors of VP adolescents' academic achievement. Method: In a geographically defined prospective whole-population sample of VP (<32 weeks gestation) and/or very low birth weight (<1500 g birth weight) (VLBW/VP; n = 281) and full-term control children (n = 286) in South Germany, ADHD subtypes were assessed at 6 years 3 months and 8 years 5 months using multiple data sources. Academic achievement was assessed at 13 years of age. Results: Compared with full-term controls, VLBW/VP children were at higher risk for ADHD inattentive subtype [6 years 3 months: odds ratio (OR) 2.8, p < 0.001; 8 years 5 months: OR 1.7, p = 0.020] but not for ADHD hyperactive-impulsive subtype (6 years 3 months: OR 1.4, p = 0.396; 8 years 5 months: OR 0.9, p = 0.820). Childhood attention measures predicted academic achievement in VLBW/VP and also full-term adolescents, whereas hyperactive/impulsive behaviour did not. Conclusions: Attention is an important prerequisite for learning and predicts long-term academic underachievement. As ADHD inattentive subtype and cognitive impairments are frequent in VLBW/VP children, their study may help to identify the neurofunctional pathways from early brain development and dysfunction to attention problems and academic underachievement