3,111 research outputs found
Recommended from our members
Non-Coding RNA Sequencing of Equine Endometrium During Maternal Recognition of Pregnancy.
Maternal recognition of pregnancy (MRP) in the mare is not well defined. In a non-pregnant mare, prostaglandin F2α (PGF) is released on day 14 post-ovulation (PO) to cause luteal regression, resulting in loss of progesterone production. Equine MRP occurs prior to day 14 to halt PGF production. Studies have failed to identify a gene candidate for MRP, so attention has turned to small, non-coding RNAs. The objective of this study was to evaluate small RNA (<200 nucleotides) content in endometrium during MRP. Mares were used in a cross-over design with each having a pregnant and non-mated cycle. Each mare was randomly assigned to collection day 11 or 13 PO (n = 3/day) and endometrial biopsies were obtained. Total RNA was isolated and sequencing libraries were prepared using a small RNA library preparation kit and sequenced on a HiSeq 2000. EquCab3 was used as the reference genome and DESeq2 was used for statistical analysis. On day 11, 419 ncRNAs, representing miRNA, snRNA, snoRNA, scaRNA, and vaultRNA, were different between pregnancy statuses, but none on day 13. Equine endometrial ncRNAs with unknown structure and function were also identified. This study is the first to describe ncRNA transcriptome in equine endometrium. Identifying targets of these ncRNAs could lead to determining MRP
The Non-thermal Radio Jet Toward the NGC 2264 Star Formation Region
We report sensitive VLA 3.6 cm radio observations toward the head of the Cone
nebula in NGC 2264, made in 2006. The purpose of these observations was to
study a non-thermal radio jet recently discovered, that appears to emanate from
the head of the Cone nebula. The jet is highly polarized, with well-defined
knots, and one-sided. The comparison of our images with 1995 archive data
indicates no evidence of proper motions nor polarization changes. We find
reliable flux density variations in only one knot, which we tentatively
identify as the core of a quasar or radio galaxy. An extragalactic location
seems to be the best explanation for this jet.Comment: 12 pages, 5 figure
Defects and boundary layers in non-Euclidean plates
We investigate the behavior of non-Euclidean plates with constant negative
Gaussian curvature using the F\"oppl-von K\'arm\'an reduced theory of
elasticity. Motivated by recent experimental results, we focus on annuli with a
periodic profile. We prove rigorous upper and lower bounds for the elastic
energy that scales like the thickness squared. In particular we show that are
only two types of global minimizers -- deformations that remain flat and saddle
shaped deformations with isolated regions of stretching near the edge of the
annulus. We also show that there exist local minimizers with a periodic profile
that have additional boundary layers near their lines of inflection. These
additional boundary layers are a new phenomenon in thin elastic sheets and are
necessary to regularize jump discontinuities in the azimuthal curvature across
lines of inflection. We rigorously derive scaling laws for the width of these
boundary layers as a function of the thickness of the sheet
Maldi-imaging for proteomics of protease inhibitors
Comunicaciones a congreso
Rapid grain growth in post-AGB disc systems from far-infrared and sub-millimetre photometry
The timescales on which astronomical dust grows remain poorly understood,
with important consequences for our understanding of processes like
circumstellar disk evolution and planet formation.A number of post-asymptotic
giant branch stars are found to host optically thick, dust- and gas-rich
circumstellar discs in Keplerian orbits. These discs exhibit evidence of dust
evolution, similar to protoplanetary discs; however since post-AGB discs have
substantially shorter lifetimes than protoplanetary discs they may provide new
insights on the grain-growth process. We examine a sample of post-AGB stars
with discs to determine the FIR and sub-mm spectral index by homogeneously
fitting a sample of data from \textit{Herschel}, the SMA and the literature. We
find that grain growth to at least hundreds of micrometres is ubiquitous in
these systems, and that the distribution of spectral indices is more similar to
that of protoplanetary discs than debris discs. No correlation is found with
the mid-infrared colours of the discs, implying that grain growth occurs
independently of the disc structure in post-AGB discs. We infer that grain
growth to mm sizes must occur on timescales yr, perhaps by
orders of magnitude, as the lifetimes of these discs are expected to be
~yr and all objects have converged to the same state. This
growth timescale is short compared to the results of models for protoplanetary
discs including fragmentation, and may provide new constraints on the physics
of grain growth.Comment: 13 pages, 7 figures. Accepted for publication in MNRA
A massive cluster of Red Supergiants at the base of the Scutum-Crux arm
We report on the unprecedented Red Supergiant (RSG) population of a massive
young cluster, located at the base of the Scutum-Crux Galactic arm. We identify
candidate cluster RSGs based on {\it 2MASS} photometry and medium resolution
spectroscopy. With follow-up high-resolution spectroscopy, we use CO-bandhead
equivalent width and high-precision radial velocity measurements to identify a
core grouping of 26 physically-associated RSGs -- the largest such cluster
known to-date. Using the stars' velocity dispersion, and their inferred
luminosities in conjuction with evolutionary models, we argue that the cluster
has an initial mass of 40,000\msun, and is therefore among the most
massive in the galaxy. Further, the cluster is only a few hundred parsecs away
from the cluster of 14 RSGs recently reported by Figer et al (2006). These two
RSG clusters represent 20% of all known RSGs in the Galaxy, and now offer the
unique opportunity to study the pre-supernova evolution of massive stars, and
the Blue- to Red-Supergiant ratio at uniform metallicity. We use GLIMPSE,
MIPSGAL and MAGPIS survey data to identify several objects in the field of the
larger cluster which seem to be indicative of recent region-wide starburst
activity at the point where the Scutum-Crux arm intercepts the Galactic bulge.
Future abundance studies of these clusters will therefore permit the study of
the chemical evolution and metallicity gradient of the Galaxy in the region
where the disk meets the bulge.Comment: 49 pages, 22 figures. Accepted for publication in ApJ. Version with
hi-res figures can be found at http://www.cis.rit.edu/~bxdpci/RSGC2.pd
- …