Static inverter Patent

Development and characteristics of oscillating static inverte

A program of research and development of low input voltage conversion and regulation Quarterly report, 15 Dec. 1965 - 14 Mar. 1966

Synchronization of redundant low input voltage conversion and regulation systems for use with satellite energy conversion source

A program of research and development of low input voltage conversion and regulation First quarterly report, 14 Jun. - 14 Sep. 1965

Switching and circuit studies for development of low input voltage converter and regulato

Low voltage dc to dc converter-regulator with minimum external magnetic field disturbance final report, 1 jun. 1954 - 30 jun. 1965

Engineering developments for low voltage dc to dc converter-regulator with minimum external magnetic field disturbanc

Low voltage dc to dc converter-regulator with minimum external magnetic field disturbance third quarterly progress report, 1 dec. 1964 - 28 feb. 1965

Low voltage dc to dc converter regulator with minimum external magnetic field disturbance - choke cell assembly and magnetic disturbance mapping of choke cell and coaxial converte

A program of research and development of low input voltage conversion and regulation Final report, 14 Jun. 1965 - 14 Jul. 1966

Techniques and hardware for low input voltage converter-regulator syste

Slo3 K+ Channels: Voltage and pH Dependence of Macroscopic Currents

The mouse Slo3 gene (KCNMA3) encodes a K+ channel that is regulated by changes in cytosolic pH. Like Slo1 subunits responsible for the Ca2+ and voltage-activated BK-type channel, the Slo3 α subunit contains a pore module with homology to voltage-gated K+ channels and also an extensive cytosolic C terminus thought to be responsible for ligand dependence. For the Slo3 K+ channel, increases in cytosolic pH promote channel activation, but very little is known about many fundamental properties of Slo3 currents. Here we define the dependence of macroscopic conductance on voltage and pH and, in particular, examine Slo3 conductance activated at negative potentials. Using this information, the ability of a Horrigan-Aldrich–type of general allosteric model to account for Slo3 gating is examined. Finally, the pH and voltage dependence of Slo3 activation and deactivation kinetics is reported. The results indicate that Slo3 differs from Slo1 in several important ways. The limiting conductance activated at the most positive potentials exhibits a pH-dependent maximum, suggesting differences in the limiting open probability at different pH. Furthermore, over a 600 mV range of voltages (−300 to +300 mV), Slo3 conductance shifts only about two to three orders of magnitude, and the limiting conductance at negative potentials is relatively voltage independent compared to Slo1. Within the context of the Horrigan-Aldrich model, these results indicate that the intrinsic voltage dependence (zL) of the Slo3 closed–open equilibrium and the coupling (D) between voltage sensor movement are less than in Slo1. The kinetic behavior of Slo3 currents also differs markedly from Slo1. Both activation and deactivation are best described by two exponential components, both of which are only weakly voltage dependent. Qualitatively, the properties of the two kinetic components in the activation time course suggest that increases in pH increase the fraction of more rapidly opening channels