3-Amino-1-methyl­pyrazin-1-ium iodide

In the cation of the title compound, C5H8N3 +·I−, the C—N(H2) bond distance [1.338 (8) Å] is at the lower end of the range for aryl amines. In the crystal structure, cations and anions are linked via N—H⋯I hydrogen bonds, forming centrosymmetric four-component clusters

Diode-pumped, mechanically-flexible polymer DFB laser encapsulated by glass membranes

A diode-pumped, mechanically-flexible organic distributed-feedback laser that is fully encapsulated with ultra-thin glass is reported. The organic laser is excited by 450nm laser diode and emits at 537 nm with an oscillation threshold of 290 W/cm2. The encapsulation format of the device results in a photostability that is improved by two orders of magnitude compared to a non-encapsulated reference device while maintaining mechanical flexibility thanks to an overall device thickness below 105 μm. The laser is also wavelength-tunable between 535 nm and 545 nm by bending the ultra-thin glass structure

Curative pelvic exenteration for recurrent cervical carcinoma in the era of concurrent chemotherapy and radiation therapy. A systematic review

International audienceOBJECTIVE: Pelvic exenteration requires complete resection of the tumor with negative margins to be considered a curative surgery. The purpose of this review is to assess the optimal preoperative evaluation and surgical approach in patients with recurrent cervical cancer to increase the chances of achieving a curative surgery with decreased morbidity and mortality in the era of concurrent chemoradiotherapy. METHODS: Review of English publications pertaining to cervical cancer within the last 25 years were included using PubMed and Cochrane Library searches. RESULTS: Modern imaging (MRI and PET-CT) does not accurately identify local extension of microscopic disease and is inadequate for preoperative planning of extent of resection. Today, only half of pelvic exenteration procedures obtain uninvolved surgical margins. CONCLUSION: Clear margins are required for curative pelvic exenterations, but are poorly predictable by pre-operative assessment. More extensive surgery, i.e. the infra-elevator exenteration with vulvectomy, is a logical surgical choice to increase the rate of clear margins and to improve patient survival following surgery for recurrent cervical carcinoma

DENSITÉ DES NIVEAUX DE BASSE ÉNERGIE ET INSTABILITÉS DE SURFACE DANS LES NOYAUX LOURDS DE TRANSITION

Une analyse statistique des niveaux nucléaires de Au, Pt, Hg a été réalisée avec la méthode d'Ericson. Les distributions expérimentales du nombre de niveaux d'or impair sont comparées aux distributions théoriques correspondant aux modèles vibrationnels (Alaga, Kisslinger-Sorensen) et rotationnels (Stephens, Meyer-ter-Vehn). Le modèle d'Alaga donne la description la plus complète des niveaux de 193,195Au et s'accorde avec la partie inférieure de la distribution de haute énergie de Gilbert-Cameron (déduite du modèle statistique et des données de capture neutronique). La méthode d'Ericson révèle d'autres aspects intéressants des isotopes de Pt et Hg (p. ex. dépendance entre la densité des niveaux et la forme des noyaux ou des corrélations de paires, évidence pour des transitions de phase). En conséquence, cette méthode est un outil approprié pour l'orientation des recherches expérimentales aussi bien que théoriques des noyaux de transition

Changes in seabed morphology, mud temperature and free gas venting at the H ̊akon Mosby mud volcano, offshore northern Norway, over the time period 2003-2006

The HAyenkon Mosby mud volcano is a 1.5-km-diameter geological structure located on the Southwest Barents Sea slope at a water depth of 1,270 m. High-definition seabed mapping of the mud volcano has been carried out in 2003 and 2006. A comparative analysis of the bathymetry and backscatter maps produced from the two surveys shows subtle morphological changes over the entire crater of the mud volcano, interpreted to be the consequence of mud eruption events. Mud temperature measurements point to a persistently warm mud at shallow depth in the crater. This is explained by upward fluid advection, rather than conductive cooling of mud flows. The small-scale spatial variability in the temperature distribution may be related to mud outflows or changes in the fluid flow regime. Furthermore, the locations of free gas venting observed in 2006 were found to differ from those of 2003. Our observations of overall similar topographic profiles across the mud volcano in 2003 and 2006 suggest that eruption events would have been modest. Nevertheless, the data bring evidence of significant change in activity even over short time intervals of only 3 years. This may be a characteristic shared by other submarine mud volcanoes, notably those considered to be in a quiescent stage

Separation between coherent and turbulent fluctuations. What can we learn from the Empirical Mode Decomposition?

The performances of a new data processing technique, namely the Empirical Mode Decomposition, are evaluated on a fully developed turbulent velocity signal perturbed by a numerical forcing which mimics a long-period flapping. First, we introduce a "resemblance" criterion to discriminate between the polluted and the unpolluted modes extracted from the perturbed velocity signal by means of the Empirical Mode Decomposition algorithm. A rejection procedure, playing, somehow, the role of a high-pass filter, is then designed in order to infer the original velocity signal from the perturbed one. The quality of this recovering procedure is extensively evaluated in the case of a "mono-component" perturbation (sine wave) by varying both the amplitude and the frequency of the perturbation. An excellent agreement between the recovered and the reference velocity signals is found, even though some discrepancies are observed when the perturbation frequency overlaps the frequency range corresponding to the energy-containing eddies as emphasized by both the energy spectrum and the structure functions. Finally, our recovering procedure is successfully performed on a time-dependent perturbation (linear chirp) covering a broad range of frequencies.Comment: 23 pages, 13 figures, submitted to Experiments in Fluid

RGB and white-emitting organic lasers on flexible glass

Two formats of multiwavelength red, green and blue (RGB) laser on mechanically-flexible glass are demonstrated. In both cases, three all-organic, vertically-emitting distributed feedback (DFB) lasers are assembled onto a common ultra-thin glass membrane substrate and fully encapsulated by a thin polymer overlayer and an additional 50µm-thick glass membrane in order to improve the performance. The first device format has the three DFB lasers sitting next to each other on the glass substrate. The DFB lasers are simultaneously excited by a single overlapping optical pump, emitting spatially separated red, green and blue laser output with individual thresholds of, respectively, 28 µJ/cm2, 11 µJ/cm2 and 32 µJ/cm2 (for 5 ns pump pulses). The second device format has the three DFB lasers, respectively the red, green and blue laser, vertically stacked onto the flexible glass. This device format emits a white laser output for an optical pump fluence above 42 µJ/cm2