On astrophysical solution to ultra high energy cosmic rays

We argue that an astrophysical solution to UHECR problem is viable. The pectral features of extragalactic protons interacting with CMB are calculated in model-independent way. Using the power-law generation spectrum $\propto E^{-\gamma_g}$ as the only assumption, we analyze four features of the proton spectrum: the GZK cutoff, dip, bump and the second dip. We found the dip, induced by electron-positron production on CMB, as the most robust feature, existing in energy range $1\times 10^{18} - 4\times 10^{19}$ eV. Its shape is stable relative to various phenomena included in calculations. The dip is well confirmed by observations of AGASA, HiRes, Fly's Eye and Yakutsk detectors. The best fit is reached at $\gamma_g =2.7$, with the allowed range 2.55 - 2.75. The dip is used for energy calibration of the detectors. After the energy calibration the fluxes and spectra of all three detectors agree perfectly, with discrepancy between AGASA and HiRes at $E> 1\times 10^{20}$ eV being not statistically significant. The agreement of the dip with observations should be considered as confirmation of UHE proton interaction with CMB. The dip has two flattenings. The high energy flattening at $E \approx 1\times 10^{19}$ eV automatically explains ankle. The low-energy flattening at $E \approx 1\times 10^{18}$ eV provides the transition to galactic cosmic rays. This transition is studied quantitatively. The UHECR sources, AGN and GRBs, are studied in a model-dependent way, and acceleration is discussed. Based on the agreement of the dip with existing data, we make the robust prediction for the spectrum at $1\times 10^{18} - 1\times 10^{20}$ eV to be measured in the nearest future by Auger detector.Comment: Revised version as published in Phys.Rev. D47 (2006) 043005 with a small additio

Search for Point Sources of Ultra-High Energy Cosmic Rays Above 40 EeV Using a Maximum Likelihood Ratio Test

We present the results of a search for cosmic ray point sources at energies above 40 EeV in the combined data sets recorded by the AGASA and HiRes stereo experiments. The analysis is based on a maximum likelihood ratio test using the probability density function for each event rather than requiring an a priori choice of a fixed angular bin size. No statistically significant clustering of events consistent with a point source is found.Comment: 7 pages, 7 figures. Accepted for publication in The Astrophysical Journa

An upper limit on the electron-neutrino flux from the HiRes detector

Air-fluorescence detectors such as the High Resolution Fly's Eye (HiRes) detector are very sensitive to upward-going, Earth-skimming ultrahigh energy electron-neutrino-induced showers. This is due to the relatively large interaction cross sections of these high-energy neutrinos and to the Landau-Pomeranchuk-Migdal (LPM) effect. The LPM effect causes a significant decrease in the cross sections for bremsstrahlung and pair production, allowing charged-current electron-neutrino-induced showers occurring deep in the Earth's crust to be detectable as they exit the Earth into the atmosphere. A search for upward-going neutrino-induced showers in the HiRes-II monocular dataset has yielded a null result. From an LPM calculation of the energy spectrum of charged particles as a function of primary energy and depth for electron-induced showers in rock, we calculate the shape of the resulting profile of these showers in air. We describe a full detector Monte Carlo simulation to determine the detector response to upward-going electron-neutrino-induced cascades and present an upper limit on the flux of electron-neutrinos.Comment: 13 pages, 3 figures. submitted to Astrophysical Journa

Search for Correlations between HiRes Stereo Events and Active Galactic Nuclei

We have searched for correlations between the pointing directions of ultrahigh energy cosmic rays observed by the High Resolution Fly's Eye experiment and Active Galactic Nuclei (AGN) visible from its northern hemisphere location. No correlations, other than random correlations, have been found. We report our results using search parameters prescribed by the Pierre Auger collaboration. Using these parameters, the Auger collaboration concludes that a positive correlation exists for sources visible to their southern hemisphere location. We also describe results using two methods for determining the chance probability of correlations: one in which a hypothesis is formed from scanning one half of the data and tested on the second half, and another which involves a scan over the entire data set. The most significant correlation found occurred with a chance probability of 24%.Comment: 13 pages, 1 table, 5 figure

Siphonaptera from New Guinea

53 p. : ill. ; 24 cm.Includes bibliographical references (p. 53)

TCR cross-reactivity and allorecognition: new insights into the immunogenetics of allorecognition

Alloreactive T cells are core mediators of graft rejection and are a potent barrier to transplantation tolerance. It was previously unclear how T cells educated in the recipient thymus could recognize allogeneic HLA molecules. Recently it was shown that both naïve and memory CD4+ and CD8+ T cells are frequently cross-reactive against allogeneic HLA molecules and that this allorecognition exhibits exquisite peptide and HLA specificity and is dependent on both public and private specificities of the T cell receptor. In this review we highlight new insights gained into the immunogenetics of allorecognition, with particular emphasis on how viral infection and vaccination may specifically activate allo-HLA reactive T cells. We also briefly discuss the potential for virus-specific T cell infusions to produce GvHD. The progress made in understanding the molecular basis of allograft rejection will hopefully be translated into improved allograft function and/or survival, and eventually tolerance induction

Studies of systematic uncertainties in the estimation of the monocular aperture of the HiRes experiment

We have studied several sources of systematic uncertainty in calculating the aperture of the High Resolution Fly's Eye experiment (HiRes) in monocular mode, primarily as they affect the HiRes-II site. The energy dependent aperture is determined with detailed Monte Carlo simulations of the air showers and the detector response. We have studied the effects of changes to the input energy spectrum and composition used in the simulation. A realistic shape of the input spectrum is used in our analysis in order to avoid biases in the aperture estimate due to the limited detector resolution. We have examined the effect of exchanging our input spectrum with a simple E^{-3} power law in the "ankle" region. Uncertainties in the input composition are shown to be significant for energies below about 10^{18} eV for data from the HiRes-II detector. Another source of uncertainties is the choice of the hadronic interaction model in the air shower generator. We compare the aperture estimate for two different models: QGSJet01 and SIBYLL 2.1. We also describe the implications of employing an atmospheric database with hourly measurements of the aerosol component, instead of using an average as has been used in our previously published measurements of the monocular spectra

A Study of the Composition of Ultra High Energy Cosmic Rays Using the High Resolution Fly's Eye

The composition of Ultra High Energy Cosmic Rays (UHECR) is measured with the High Resolution Fly's Eye cosmic ray observatory (HiRes) data using the Xmax technique. Data were collected in stereo between 1999 November and 2001 September. The data are reconstructed with well-determined geometry. Measurements of the atmospheric transmission are incorporated in the reconstruction. The detector resolution is found to be 30 g cm^-2 in Xmax and 13% in Energy. The Xmax elongation rate between 10^18.0 eV and 10^19.4 eV is measured to be 54.5 +/- 6.5 (stat) +/- 4.5 (sys) g cm^-2 per decade. This is compared to predictions using the QGSJet01 and SIBYLL 2.1 hadronic interaction models for both protons and iron nuclei. CORSIKA-generated Extensive Air Showers (EAS) are incorporated directly into a detailed detector Monte Carlo program. The elongation rate and the Xmax distribution widths are consistent with a constant or slowly changing and predominantly light composition. A simple model containing only protons and iron nuclei is compared to QGSJet and SIBYLL. The best agreement between the model and the data is at 80% protons for QGSJet and 60% protons for SIBYLL.Comment: 52 pages, 27 figures. Revised Fig. 10 caption, improved Fig. 23, resubmitted to ApJ. (Previously revised to address referee's comments.) (Originally 37 pages, 13 figures. Submitted to ApJ