94 research outputs found

    La pràctica dels esports de combat. Un estudi preliminar sobre l’experiència prèvia dels estudiants de la llicenciatura en ciències de l’esport

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    En aquest treball es presenta un primer estudi sobre l’experiència prèvia en la pràctica d’esports de combat que tenen els estudiants de la Llicenciatura en Ciències de l’Activitat Física i l’Esport. L’estudi es va basar en la recollida i anàlisi de dades procedents d’un qüestionari administrat als estudiants de primer cicle de la llicenciatura esmentada, de les Universitats de València i de Lleó, a l’inici dels cursos acadèmics 2001-2002 i 2002‑2003. Els resultats mostren que prop del 50 % de l’alumnat tenia experiències prèvies en esports de combat. El judo, el karate i el taekwondo són, per aquest ordre, els esports més practicats. No hi ha alumnes amb experiències prèvies en esgrima o lluita grecoromana. D’altra banda, s’observa una baixa presència de les activitats de combat a les classes d’educació física reglada, car solament l’1,36 % dels estudiants van manifestar haver practicat alguna d’aquestes activitats a les classes esmentades

    La práctica de los deportes de lucha. Un estudio preliminar sobre la experiencia previa de los estudiantes de la Licenciatura en Ciencias del Deporte

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    En este trabajo se presenta un primer estudio sobre la experiencia previa en la práctica de deportes de lucha que tienen los estudiantes de la Licenciatura en Ciencias de la Actividad Física y el Deporte. El estudio se basó en la recogida y análisis de datos procedente de un cuestionario administrado a los estudiantes de primer ciclo de dicha licenciatura, de las universidades de Valencia y León, al inicio de los cursos académicos 2001-2002 y 2002-2003. Los resultados muestran que cerca del 50 % del alumnado tenía experiencias previas en deportes de lucha. El judo, el kárate y el taekwondo son, por este orden, los deportes más practicados. No hay alumnos con experiencias previas en esgrima o lucha grecorromana. Por otro lado, se observa una baja presencia de las actividades de lucha en las clases de educación física reglada, ya que sólo el 1,36 % de los estudiantes manifestaron haber practicado alguna de estas actividades en dichas clases

    Comparative Cytotoxic Activity of Hydroxytyrosol and Its Semisynthetic Lipophilic Derivatives in Prostate Cancer Cells

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    A high adherence to a Mediterranean diet has been related to numerous beneficial effects in human health, including a lower incidence and mortality of prostate cancer (PCa). Olive oil is an important source of phenolic bioactive compounds, mainly hydroxytyrosol (HT), of this diet. Because of the growing interest of this compound and its derivatives as a cancer chemopreventive agent, we aimed to compare the in vitro effect of HT isolated from olive mill wastewaters and five semisynthetic alkyl ether, ester, and nitro-derivatives against prostate cancer (PCa) cell lines. The effect in cell proliferation was determined in RWPE-1, LNCaP, 22Rv1, and PC-3 cells by resazurin assay, the effect in cell migration by wound healing assay, and tumorsphere and colony formation were evaluated. The changes in key signaling pathways involved in carcinogenesis were assessed by using a phosphorylation pathway profiling array and by Western blotting. Antiproliferative effects of HT and two lipophilic derivatives [hydroxytyrosyl acetate (HT-Ac)/ethyl hydroxytyrosyl ether (HT-Et)] were significantly higher in cancerous PC-3 and 22Rv1 cells than in non-malignant RWPE-1 cells. HT/HT-Ac/HT-Et significantly reduced migration capacity in RWPE-1 and PC-3 and prostatosphere size and colony formation in 22Rv1, whereas only HT-Ac and HT-Et reduced these functional parameters in PC-3. The cytotoxic effect in 22Rv1 cells was correlated with modifications in the phosphorylation pattern of key proteins, including ERK1/2 and AKT. Consistently, HT-Ac and HT-Et decreased p-AKT levels in PC-3. In sum, our results suggest that HT and its lipophilic derivatives could be considered as potential therapeutic tools in PCa

    Western men and Eastern arts: The significance of Eastern martial arts disciplines in British men's narratives of masculinity

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    Previous Western sociological research on Eastern martial arts has identified a tension between ‘traditional’ Eastern forms of practice and ‘modernized’ Western methods of training and competition. In particular, the ‘sportization’ of Eastern styles, where combat-centred arts based upon moral philosophies have transformed more or less into competitive activities following Western models of rationalized sport, has been an important theme. However, it is also suggested that Eastern martial arts hold special significance in the West for their seemingly esoteric nature. In this regard, such martial arts are considered significant because they are not ‘sports’, but rather disciplines, with fairly different connotations for practitioners. Drawing on interview data, this paper explores how Western practitioners of Eastern martial arts articulate this difference, principally by examining the place of martial artistry in British men's narratives of masculinity. Comparing themselves favourably to assumed, typical visions of Western sporting masculinity, such men draw upon the imagined uniqueness of their martial arts to construct a sense of moral superiority over other men. In so doing, they contribute to a rejection of what they believe to be ‘mainstream’ sporting Western masculinity, thus indicating the role that ‘alternative’ visions of physical culture can play in men's active constructions of gender

    Expression of Xhdsi-1VOC, a novel member of the vicinal oxygen chelate (VOC) metalloenzyme superfamily, is up-regulated in leaves and roots during desiccation in the resurrection plant Xerophyta humilis (Bak) Dur and Schinz

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    The annotation of novel plant genes is frequently based on sequence and structural similarity to known protein motifs. Understanding the biological function of these genes is dependent on identifying conditions under which they are activated, however. The resurrection plant, Xerophyta humilis is a good model system for identifying and characterizing genes which are important for desiccation tolerance. Desiccation induced-1 (dsi-1VOC), a previously uncharacterized plant gene, is up-regulated during desiccation in leaves, roots, and seeds in X. humilis. The X. humilis desiccation induced-1 gene, Xhdsi-1VOC, shares structural homology with the vicinal oxygen chelate (VOC) metalloenzyme superfamily. Proteins in this superfamily share little sequence similarity, but are characterized by a common βαβββ structural fold. A number of plant orthologues of XhDsi-1VOC have been identified, including Arabidopsis thaliana At1g07645, which is currently annotated as a glyoxalase I-like gene, and many ESTs derived from seed cDNA libraries. Xhdsi-1VOC and its orthologues do not, however, contain the glutathione and zinc binding sites conserved in glyoxalase I genes. Furthermore, expression of Xhdsi-1VOC in yeast failed to rescue a yeast glyoxalase I mutant. Messenger RNA transcripts for At1g07645 accumulate during seed maturation, but are not induced by water loss, salt or mannitol stress in vegetative tissue in Arabidopsis. It is concluded that dsi-1VOC is a seed-specific gene in desiccation-sensitive plants that is activated by water loss in vegetative tissues in the resurrection plant X. humilis and plays an important role in allowing plant tissues to survive loss of 95% of their relative water content
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