Analytical fuel property effects, small combustors, phase 1

The effects of nonstandard aviation fuels on a typical small gas turbine combustor was analyzed. The T700/CT7 engine family was chosen as being representative of the class of aircraft power plants desired. Fuel properties, as specified by NASA, are characterized by low hydrogen content and high aromatics levels. Higher than normal smoke output and flame radiation intensity for the current T700 combustor which serves as a baseline were anticipated. It is, therefore, predicted that out of specification smoke visibility and higher than normal shell temperatures will exist when using NASA ERBS fuels with a consequence of severe reduction in cyclic life. Three new designs are proposed to compensate for the deficiencies expected with the existing design. They have emerged as the best of the eight originally proposed redesigns or combinations thereof. After the five choices that were originally made by NASA on the basis of competing performance factors, General Electric narrowed the field to the three proposed

The total nucleon-nucleon cross section at large N_c

It is shown that at sufficiently large $N_c$ for incident momenta which are much larger than the QCD, the total nucleon-nucleon cross section is independent of incident momentum and given by $\sigma^{\rm total}=2 \pi \log^2(N_c) / (m^2_{\pi})$. This result is valid in the extreme large $N_c$ regime of $\log(N_c) \gg 1$ and has corrections of relative order $\log (\log(N_c))/\log(N_c)$. A possible connection of this result to the Froissart-Martin bound is discussed.Comment: 4 page

N-body Monte Carlo simulation of specific lunar orbiter missions

N-body Monte Carlo simulation of specific lunar orbiter mission

Constrained Molecular Dynamics Simulations of Atomic Ground-States

Constrained molecular dynamics(CoMD) model, previously introduced for nuclear dynamics, has been extended to the atomic structure and collision calculations. Quantum effects corresponding to the Pauli and Heisenberg principle are enforced by constraints, in a parameter-free way. Our calculations for small atomic system, H, He, Li, Be, F reproduce the ground-state binding energies within 3%, compared with the results of quantum mechanical Hartree-Fock calculations.Comment: 3 pages, 2 figure

Non-equilibrium steady state of sparse systems

A resistor-network picture of transitions is appropriate for the study of energy absorption by weakly chaotic or weakly interacting driven systems. Such "sparse" systems reach a novel non-equilibrium steady state (NESS) once coupled to a bath. In the stochastic case there is an analogy to the physics of percolating glassy systems, and an extension of the fluctuation-dissipation phenomenology is proposed. In the mesoscopic case the quantum NESS might differ enormously from the stochastic NESS, with saturation temperature determined by the sparsity. A toy model where the sparsity of the system is modeled using a log-normal random ensemble is analyzed.Comment: 6 pages, 6 figures, EPL accepted versio

Cramer-Rao Lower Bound for Point Based Image Registration with Heteroscedastic Error Model for Application in Single Molecule Microscopy

The Cramer-Rao lower bound for the estimation of the affine transformation parameters in a multivariate heteroscedastic errors-in-variables model is derived. The model is suitable for feature-based image registration in which both sets of control points are localized with errors whose covariance matrices vary from point to point. With focus given to the registration of fluorescence microscopy images, the Cramer-Rao lower bound for the estimation of a feature's position (e.g. of a single molecule) in a registered image is also derived. In the particular case where all covariance matrices for the localization errors are scalar multiples of a common positive definite matrix (e.g. the identity matrix), as can be assumed in fluorescence microscopy, then simplified expressions for the Cramer-Rao lower bound are given. Under certain simplifying assumptions these expressions are shown to match asymptotic distributions for a previously presented set of estimators. Theoretical results are verified with simulations and experimental data

Subwavelength position sensing using nonlinear feedback and wave chaos

We demonstrate a position-sensing technique that relies on the inherent sensitivity of chaos, where we illuminate a subwavelength object with a complex structured radio-frequency field generated using wave chaos and a nonlinear feedback loop. We operate the system in a quasi-periodic state and analyze changes in the frequency content of the scalar voltage signal in the feedback loop. This allows us to extract the object's position with a one-dimensional resolution of ~\lambda/10,000 and a two-dimensional resolution of ~\lambda/300, where \lambda\ is the shortest wavelength of the illuminating source.Comment: 4 pages, 4 figure

Comparing the Weighted Density Approximation with the LDA and GGA for Ground State Properties of Ferroelectric Perovskites

First-principles calculations within the weighted density approximation (WDA) were performed for ground state properties of ferroelectric perovskites PbTiO$_3$, BaTiO$_3$, SrTiO$_3$, KNbO$_3$ and KTaO$_3$. We used the plane-wave pseudopotential method, a pair distribution function $G$ based on the uniform electron gas, and shell partitioning. Comparing with the local density approximation (LDA) and the general gradient approximation (GGA), we found that the WDA significantly improves the equilibrium volume of these materials in cubic symmetry over both the LDA and GGA; Ferroelectric instabilities calculated by the WDA agree with the LDA and GGA very well; At the experimental ferroelectric lattice, optimized atom positions by the WDA are in good agreement with measured data; However the WDA overestimates the strain of tetragonal PbTiO$_3$ at experimental volume; The WDA overestimates the volume of fully relaxed structures, but the GGA results are even worse. Some calculations were also done with other models for $G$. It is found that a $G$ with longer range behavior yields improved relaxed structures. Possible avenues for improving the WDA are discussed.Comment: 19 pages, 3 figures, submitted to PR

The WISE InfraRed Excesses around Degenerates (WIRED) Survey

The Wide-field Infrared Survey Explorer (WISE) is a NASA medium class Explorer mission that performed an all sky survey in four infrared bands. We present an overview of the WISE InfraRed Excesses around Degenerates (WIRED) Survey, which has the goals of characterizing white dwarf stars in the WISE bands, confirming objects known to have infrared excess from past observations, and revealing new examples of white dwarfs with infrared excess that can be attributed to unresolved companions or debris disks. We obtained preliminary WISE detections (S/N > 2) in at least one band of 405 white dwarfs from the 9316 unique possible targets in the Sloan Digital Sky Survey Data Release 4 Catalog of Spectroscopically Identified White Dwarfs (not all potential targets were available in the sky coverage used here). A companion paper in this volume discusses specific results from our target detections

Rapamycin induces transactivation of the EGFR and increases cell survival.

The mammalian target of rapamycin (mTOR) signaling network regulates cell growth, proliferation and cell survival. Deregulated activation of this pathway is a common event in diverse human diseases such as cancers, cardiac hypertrophy, vascular restenosis and nephrotic hypertrophy. Although mTOR inhibitor, rapamycin, has been widely used to inhibit the aberrant signaling due to mTOR activation that plays a major role in hyperproliferative diseases, in some cases rapamycin does not attenuate the cell proliferation and survival. Thus, we studied the mechanism(s) by which cells may confer resistance to rapamycin. Our data show that in a variety of cell types the mTOR inhibitor rapamycin activates extracellularly regulated kinases (Erk1/2) signaling. Rapamycin-mediated activation of the Erk1/2 signaling requires (a) the epidermal growth factor receptor (EGFR), (b) its tyrosine kinase activity and (c) intact autophosphorylation sites on the receptor. Rapamycin treatment increases tyrosine phosphorylation of EGFR without the addition of growth factor and this transactivation of receptor involves activation of c-Src. We also show that rapamycin treatment triggers activation of cell survival signaling pathway by activating the prosurvival kinases Erk1/2 and p90RSK. These studies provide a novel paradigm by which cells escape the apoptotic actions of rapamycin and its derivatives that inhibit the mTOR pathway