670 research outputs found

    Hilbert series of fiber cones of ideals of almost minimal mixed multiplicity

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    Let (R, m) be a Cohen-Macaulay local ring and I be an m-primary ideal. We introduce ideals of almost minimal mixed multiplicty which are analogues of ideals studied by J. Sally. The main theorem describes the Hilbert series of fiber cones of these ideals.Comment: 12 page

    Pharmaceuticals: Antibiotics and vegetarians

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    Excitation of the 3.071mm Hyperfine Line in Li-Like 57-Fe in Astrophysical Plasmas

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    As noted first by Sunyaev & Churazov (1984), the 3.071 mm hyperfine line from 57Fe+23^{57}Fe^{+23} might be observable in astrophysical plasmas. We assess the atomic processes which might contribute to the excitation of this line. We determine the intensity of the hyperfine line from an isothermal, coronal plasma in collisional ionization equilibrium and for a coronal plasma cooling isobarically due to its own radiation. Comparisons of the hyperfine line to other lines emitted by the same ion, Fe+23^{+23}, are shown to be useful for deriving the isotopic fraction of 57^{57}Fe. We calculate the ratios of the hyperfine line to the 2s--2p EUV lines at 192 \AA and 255 \AA, and the 2s--3p X-ray doublet at 10.6 \AA.Comment: 28 pages text+figures, Accepted to ApJ in Jan 98, also at http://www.astro.virginia.edu/~nld2n/research.htm

    J08069+1527: A newly discovered high amplitude, hybrid subdwarf B pulsator

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    We present our discovery of a new hybrid pulsating subdwarf B star, J08069+1527. The effective temperature and surface gravity of 28,500±\pm400\,K and 5.37±\pm0.04\,dex, respectively, place this object inside the instability strip and also among other pulsating hot subdwarfs of a hybrid nature, right next to another fascinating star: Balloon\,090100001. From this proximity, we anticipated this star could pulsate in both high and low frequency modes. Indeed, our analysis of photometric data confirmed our prediction. We detected two peaks in the high frequency region and two other peaks at low frequencies. In addition, the amplitude of the dominant mode is very high and comparable to the dominant peaks in other hybrid subdwarf B stars. Since this star is bright, we performed time-series low resolution spectroscopy. Despite a low signal-to-noise (S/N) ratio, we were able to detect the main peak from these data. All our results strongly indicate that J08069+1527 is a high amplitude pulsating hot subdwarf B star of hybrid nature. By analogy to the other pulsating sdB star, we judge that the dominant mode we detected here has radial nature. Future stellar modeling should provide us with quite good constrains as p- and g-modes presented in this star are driven in different parts of its interior.Comment: 7 pages, 10 figures, accepted for publication in MNRA

    Importance and hurdles to drug discovery for neurological disease

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110873/1/ana23997.pd

    The clinical assessment study of the foot (CASF): study protocol for a prospective observational study of foot pain and foot osteoarthritis in the general population.

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    BACKGROUND: Symptomatic osteoarthritis (OA) affects approximately 10% of adults aged over 60 years. The foot joint complex is commonly affected by OA, yet there is relatively little research into OA of the foot, compared with other frequently affected sites such as the knee and hand. Existing epidemiological studies of foot OA have focussed predominantly on the first metatarsophalangeal joint at the expense of other joints. This three-year prospective population-based observational cohort study will describe the prevalence of symptomatic radiographic foot OA, relate its occurrence to symptoms, examination findings and life-style-factors, describe the natural history of foot OA, and examine how it presents to, and is diagnosed and managed in primary care. METHODS: All adults aged 50 years and over registered with four general practices in North Staffordshire, UK, will be invited to participate in a postal Health Survey questionnaire. Respondents to the questionnaire who indicate that they have experienced foot pain in the preceding twelve months will be invited to attend a research clinic for a detailed clinical assessment. This assessment will consist of: clinical interview; physical examination; digital photography of both feet and ankles; plain x-rays of both feet, ankles and hands; ultrasound examination of the plantar fascia; anthropometric measurement; and a further self-complete questionnaire. Follow-up will be undertaken in consenting participants by postal questionnaire at 18 months (clinic attenders only) and three years (clinic attenders and survey participants), and also by review of medical records. DISCUSSION: This three-year prospective epidemiological study will combine survey data, comprehensive clinical, x-ray and ultrasound assessment, and review of primary care records to identify radiographic phenotypes of foot OA in a population of community-dwelling older adults, and describe their impact on symptoms, function and clinical examination findings, and their presentation, diagnosis and management in primary care

    RAT J0455+1305: A rare hybrid pulsating subdwarf B star

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    We present results on the second-faintest pulsating subdwarf B (sdB) star known, RAT J0455+1305, derived from photometric data obtained in 2009. It shows both short and long periods oscillations, theoretically assigned as pressure and gravity modes. We identify six short-period frequencies (with one being a combination) and six long-period frequencies. This star is the fourth hybrid sdB star discovered so far which makes it of special interest as each type of mode probes a different part of the star. This star is similar to the sdB hybrid pulsator Balloon 090100001 in that it exhibits short-period mode groupings, which can be used to identify pulsation parameters and constrain theoretical models.Comment: published in MNRA
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