Wheelchair-based game design for older adults

Few leisure activities are accessible to institutionalized older adults using wheelchairs; in consequence, they experience lower levels of perceived health than able-bodied peers. Video games have been shown to be an engaging leisure activity for older adults. In our work, we address the design of wheelchair-accessible motion-based games. We present KINECTWheels, a toolkit designed to integrate wheelchair movements into motion-based games, and Cupcake Heaven, a wheelchair-based video game designed for older adults using wheelchairs. Results of two studies show that KINECTWheels can be applied to make motion-based games wheelchair-accessible, and that wheelchair-based games engage older adults. Through the application of the wheelchair as an enabling technology in play, our work has the potential of encouraging older adults to develop a positive relationship with their wheelchair. Copyright 2013 ACM

Visual complexity, player experience, performance and physical exertion in motion-based games for older adults

Motion-based video games can have a variety of benefits for the players and are increasingly applied in physical therapy, rehabilitation and prevention for older adults. However, little is known about how this audience experiences playing such games, how the player experience affects the way older adults interact with motion-based games, and how this can relate to therapy goals. In our work, we decompose the player experience of older adults engaging with motion-based games, focusing on the effects of manipulations of the game representation through the visual channel (visual complexity), since it is the primary interaction modality of most games and since vision impairments are common amongst older adults. We examine the effects of different levels of visual complexity on player experience, performance, and exertion in a study with fifteen participants. Our results show that visual complexity affects the way games are perceived in two ways: First, while older adults do have preferences in terms of visual complexity of video games, notable effects were only measurable following drastic variations. Second, perceived exertion shifts depending on the degree of visual complexity. These findings can help inform the design of motion-based games for therapy and rehabilitation for older adults

Issues on simulation of the railway rolling stock operation process – a system and literature review

Railway traffic simulation, taking into account operation and maintenance conditions, is not a new issue in the literature. External effects in such networks (eg. level crossings) were not taken into account in studies. The used models do not take into account sufficiently the process of degradation and recovery of the network. From the technical side, currently carried out simulations are made using similar approaches and techniques as in the initial stage of research. Well-established work in this area could be the basis for evaluation of new solutions. However, the progress in simulation tools during the last years, especially in performance and programming architecture, attempt to create a modern simulation tool. In the paper were presented the main assumptions for the evaluated event-based simulation method, with application to stiff-track transportation network

Estimates of air–sea feedbacks on sea surface temperature anomalies in the southern ocean

Sea surface temperature (SST) air–sea feedback strengths and associated decay time scales in the Southern Ocean (SO) are estimated from observations and reanalysis datasets of SST, air–sea heat fluxes, and ocean mixed layer depths. The spatial, seasonal, and scale dependence of the air–sea heat flux feedbacks is mapped in circumpolar bands and implications for SST persistence times are explored. It is found that the damping effect of turbulent heat fluxes dominates over that due to radiative heat fluxes. The turbulent heat flux feedback acts to damp SSTs in all bands and spatial scales and in all seasons, at rates varying between 5 and 25 W m⁻² K⁻¹, while the radiative heat flux feedback has a more uniform spatial distribution with a magnitude rarely exceeding 5 W m⁻² K⁻¹. In particular, the implied net air–sea feedback (turbulent + radiative) on SST south of the polar front, and in the region of seasonal sea ice, is as weak as 5–10 W m⁻² K⁻¹ in the summertime on large spatial scales. Air–sea interaction alone thus allows SST signals induced around Antarctica in the summertime to persist for several seasons. The damping effect of mixed layer entrainment on SST anomalies averages to approximately 20 W m⁻² K⁻¹ across the ACC bands in the summer-to-winter entraining season and thereby reduces summertime SST persistence to less than half of that predicted by air–sea interaction alone (i.e., 3–6 months).National Science Foundation (U.S.). Frontiers in Earth System Dynamic

Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling

AbstractThe generation of excessive amounts of reactive oxygen species (ROS) leads to cellular oxidative stress that underlies a variety of forms of hepatocyte injury and death including that from alcohol. Although ROS can induce cell damage through direct effects on cellular macromolecules, the injurious effects of ROS are mediated largely through changes in signal transduction pathways such as the mitogen-activated protein kinase c-Jun N-terminal kinase (JNK). In response to alcohol, hepatocytes have increased levels of the enzyme cytochrome P450 2E1 (CYP2E1) which generates an oxidant stress that promotes the development of alcoholic steatosis and liver injury. These effects are mediated in large part through overactivation of JNK that alters cell death pathways. Targeting the JNK pathway or its downstream effectors may be a useful therapeutic approach to the oxidative stress generated by CYP2E1 in alcoholic liver disease

Designing Competitions: How To Maintain Motivation For Losers

Competition can either increase motivation by providing an added incentive or decrease motivation by threatening participants’ sense of competence. The authors used two rounds of competition to examine whether competitions can be structured in ways that motivate high performance and do not discourage losers. Results indicated that a focus on learning and balanced ability levels mitigate any negative effect on losers’ motivation

The utilization of selection after 100-days lactation in forming a high productive Red and White herd

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Tailored Information and Automated Reminding to Improve Medication Adherence in Spanish- and English-Speaking Elders Treated for Memory Impairment.

Medication adherence is recognized as an issue of critical importance within health care, as many patients do not take their medications as prescribed. This study evaluated two interventions targeted at improving adherence in elderly patients being treated for memory impairments. Twenty-seven participants were randomly assigned to control (n = 11), automated reminding (n = 8), or tailored information conditions (n = 8). Medication adherence was evaluated with an electronic pill bottle. Generalized estimating equation (GEE) models assessed the effects of the interventions on electronically monitored medication adherence after controlling for covariates. Results showed that individuals in both intervention groups had higher levels of medication adherence than those in the control group. The presence of a caregiver was associated with substantially higher levels of adherence. Verbal memory, but not general cognitive status, predicted better adherence. Mood, health literacy, and executive functions were not associated with adherence. Results thus suggest that both automated reminding and tailored information interventions may improve medication adherence in elders, even among those with memory impairments

Relations between cognitive status and medication adherence in patients treated for memory disorders.

Medication adherence has been increasingly recognized as an important factor in elderly persons\u27 health. Various studies have shown that medication non-adherence is associated with poor health status in this population. As part of a study of the effects of two interventions to promote medication adherence in patients treated for memory problems, information on medication adherence and cognitive status was collected at 3-month intervals. Twenty-seven participants (16 men, 11 women, age 71-92 years) were assigned to control or treatment conditions and adherence was evaluated with an electronic monitoring device. Cognitive status was evaluated at 3-month intervals beginning in April of 2003 and continuing through September of 2006. We have previously reported on the effectiveness of these interventions to promote adherence. In this paper, we examine the relations of cognitive status and adherence over time using a partial least squares path model in order to evaluate the extent to which adherence to cholinesterase medications was related to cognitive status. Adherence predicted cognitive status at later time points while cognition did not, in general, predict adherence. Results thus suggest that interventions to ensure high levels of medication adherence may be important for maintaining cognitive function in affected elderly people