Pili Pono Practice: A Qualitative Study on Reimagining Native Hawaiian Food Sovereignty through MALAMA Backyard Aquaponics

Living in one of the most remote island chains in the world, Native Hawaiians developed sophisticated food cultivation systems that sustained a thriving and robust population for centuries. These systems were disrupted by colonization, which has contributed to the health disparities that Native Hawaiians face today. MALAMA, a culturally-grounded backyard aquaponics program, was developed to promote food sovereignty among Native Hawaiians. This study utilized participant interview and focus group data to identify how participating in the MALAMA program impacts the wellbeing. The findings demonstrate that MALAMA enhanced the participants’ pilina (relationship, connection) to traditional foods, land, cultural identity, family, and community, which contributed to the quick adoption of the program into Native Hawaiian communities. To address food insecurity, it is imperative to seek Indigenous-developed, community-based, and culturally-grounded programs and solutions like the MALAMA program

Waimānalo Pono Research Hui: Promoting Community-Driven and Culturally-Grounded Ethical Research

2023 Symposium Caring for Data in Hawaiʻi Keynote PresentationNative Hawaiians, or Kānaka Maoli, the first people to arrive and settle on the Hawaiian Islands, have been data scientists. To build their self-sufficient society, Native Hawaiians collected data about their natural surroundings to meticulously create sophisticated and sustainable resource management and food systems, which for centuries fed up to a million people on the islands. However, the spread of Western imperialism across the Pacific in the early 19th century led to forced assimilation and the illegal occupation of the Hawaiian Kingdom in 1893. Like other Indigenous communities and communities of color, Native Hawaiians have a long history of being the subject of unethical and exploitative research. To shift the power imbalances and colonial paradigm of research, many Native scholars, community leaders, and their allies advocate for decolonizing methodologies that revitalize and integrate cultural practices into the research. One example of decolonizing research is the Waimānalo Pono Research Hui, a community-academic group formed to promote community-driven and culturally-centered research. This presentation describes how the Waimānalo Pono Research Hui was established and the structures that have been developed to ensure research is community-driven, culturally-centered, and ethical. We will also share recommendations and lessons learned for researchers who strive to transform the way we care for data and our communities through research

A genome-wide association study implicates the pleiotropic effect of NMUR2 on asthma and COPD

Asthma and chronic obstructive pulmonary disease (COPD) are two distinct diseases that are associated with chronic inflammation. They share common features in terms of their advanced stages and genetic factors. This study aimed to identify novel genes underlying both asthma and COPD using genome-wide association study (GWAS) to differentiate between the two diseases. We performed a GWAS of asthma and COPD in 7828 Koreans from three hospitals. In addition, we investigated genetic correlations. The UK Biobank dataset was used for the replication studies. We found that rs2961757, located near neuromedin U receptor 2 (NMUR2) on chromosome 5, was genome-wide significant ([Formula: see text] = 0.44, P-valueAsthma-COPD = 3.41 × 10-8), and significant results were replicated with the UK Biobank data ([Formula: see text] = 0.04, P-valueAsthma-COPD = 0.0431). A positive genetic correlation was observed between asthma and COPD (39.8% in the Korean dataset and 49.8% in the UK Biobank dataset). In this study, 40-45% of the genetic effects were common to asthma and COPD. Moreover, NMUR2 increases the risk of asthma development and suppresses COPD development. This indicates that NMUR2 allows for better differentiation of both diseases, which can facilitate tailored medical therapy

Hawai‘i’s Caring Communities Initiative: Mobilizing Rural and Ethnic Minority Communities for Youth Suicide Prevention

Youth suicide is a serious, yet preventable, public health concern for ethnic minorities and rural communities. This paper describes the youth leadership model utilized by Hawai‘i’s Caring Communities Initiative (HCCI) and provides reflections on the important factors for success in implementing a youth and community advocacy project for youth suicide prevention. HCCI partnered with six youth and community organizations who serve ethnic minority and rural communities across the State of Hawai‘i to train youth leaders and community members in suicide prevention, in order to develop community awareness activities that are grounded in each community’s strengths and needs. The work of a youth leadership group on the island of Kaua‘i is provided as an example to demonstrate the positive rippling effects that health promotion activities can have when they are youth-driven. Important factors to consider for similar interventions that aim to engage youth to address health disparities include prioritizing relationships among all partners, building the capacity of community partners, and providing meaningful leadership opportunities for youth to serve as role models in their communities

Impacts of a university philosophy outreach program at Kailua High School

The University of Hawai’i at Mānoa’s Uehiro Academy for Philosophy and Ethics in Education (UHM Uehiro Academy) prepares, supports and sustains philosophy for children Hawai‘i (p4cHI) educators, researchers, and students in Hawai‘i and beyond. This paper documents the impact of the Uehiro Academy’s philosophy outreach program at Kailua High School (KHS), a public secondary school on the Hawaiian Island of O’ahu. It describes the twenty year partnership between the University and KHS, which built a foundation for p4cHI to become integrated across the curriculum and within the school culture. To better understand the overall impact of the UHM Uehiro Academy philosophy outreach program on KHS, researchers asked, ‘How has the UHM Uehiro Academy philosophy outreach program impacted the school culture at KHS?’ Qualitative methods were applied to design and conduct a research study, which included interviewing 68 members of the KHS community. Data analysis revealed four main themes: (1) a schoolwide learner-centred pedagogy, (2) a place for learning more than just academics, (3) a community of diverse and connected individuals, (4) a commitment to professional growth for the purpose of a better world. The paper ends with conclusions, implications of the findings, and the researchers reflecting on the findings, including the benefits and challenges of university philosophy outreach programs in the secondary school setting

Hodge Theory on Metric Spaces

Hodge theory is a beautiful synthesis of geometry, topology, and analysis, which has been developed in the setting of Riemannian manifolds. On the other hand, spaces of images, which are important in the mathematical foundations of vision and pattern recognition, do not fit this framework. This motivates us to develop a version of Hodge theory on metric spaces with a probability measure. We believe that this constitutes a step towards understanding the geometry of vision. The appendix by Anthony Baker provides a separable, compact metric space with infinite dimensional \alpha-scale homology.Comment: appendix by Anthony W. Baker, 48 pages, AMS-LaTeX. v2: final version, to appear in Foundations of Computational Mathematics. Minor changes and addition

Model binding experiments with cucurbit[7]uril and p-sulfonatocalix[4]arene support use of explicit solvation term in governing equation for binding equilibria

The thermodynamics of model host–guest-binding reactions is examined in depth using isothermal titration calorimetry. In conflict with classical thermodynamics, the results indicate that the equilibrium-binding quotient, K, is not a constant for all pairings. This outcome is predicted by an equation for binding equilibria that includes an explicit term for the change in solvation free energy that accompanies the formation of a binary complex. Application of this framework to the experimentally observed concentration dependence of K allows one to obtain the energetic contribution of the solvent, a linked equilibrium denoted here as ΔGH2O. The estimated values of ΔGH2O are large and unfavourable for the binding of selected guest molecules to two hosts, cucurbit[7]uril and p-sulfonatocalix[4]arene. Intriguingly, the estimated values of ΔGH2O are near zero for the binding of two hydrophobic guest molecules to β-cyclodextrin, leading to a thought-provoking discussion on the driving force behind the hydrophobic effect