61 research outputs found

    Blast Shock Wave Mitigation Using the Hydraulic Energy Redirection and Release Technology

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    A hydraulic energy redirection and release technology has been developed for mitigating the effects of blast shock waves on protected objects. The technology employs a liquid-filled plastic tubing as a blast overpressure transformer to transfer kinetic energy of blast shock waves into hydraulic energy in the plastic tubings. The hydraulic energy is redirected through the plastic tubings to the openings at the lower ends, and then is quickly released with the liquid flowing out through the openings. The samples of the specifically designed body armor in which the liquid-filled plastic tubings were installed vertically as the outer layer of the body armor were tested. The blast test results demonstrated that blast overpressure behind the body armor samples was remarkably reduced by 97% in 0.2 msec after the liquid flowed out of its appropriate volume through the openings. The results also suggested that a volumetric liquid surge might be created when kinetic energy of blast shock wave was transferred into hydraulic energy to cause a rapid physical movement or displacement of the liquid. The volumetric liquid surge has a strong destructive power, and can cause a noncontact, remote injury in humans (such as blast-induced traumatic brain injury and post-traumatic stress disorder) if it is created in cardiovascular system. The hydraulic energy redirection and release technology can successfully mitigate blast shock waves from the outer surface of the body armor. It should be further explored as an innovative approach to effectively protect against blast threats to civilian and military personnel

    Shear Forces during Blast, Not Abrupt Changes in Pressure Alone, Generate Calcium Activity in Human Brain Cells

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    Blast-Induced Traumatic Brain Injury (bTBI) describes a spectrum of injuries caused by an explosive force that results in changes in brain function. The mechanism responsible for primary bTBI following a blast shockwave remains unknown. We have developed a pneumatic device that delivers shockwaves, similar to those known to induce bTBI, within a chamber optimal for fluorescence microscopy. Abrupt changes in pressure can be created with and without the presence of shear forces at the surface of cells. In primary cultures of human central nervous system cells, the cellular calcium response to shockwaves alone was negligible. Even when the applied pressure reached 15 atm, there was no damage or excitation, unless concomitant shear forces, peaking between 0.3 to 0.7 Pa, were present at the cell surface. The probability of cellular injury in response to a shockwave was low and cell survival was unaffected 20 hours after shockwave exposure

    Mechanisms of Hearing Loss after Blast Injury to the Ear

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    Given the frequent use of improvised explosive devices (IEDs) around the world, the study of traumatic blast injuries is of increasing interest. The ear is the most common organ affected by blast injury because it is the bodyメs most sensitive pressure transducer. We fabricated a blast chamber to re-create blast profiles similar to that of IEDs and used it to develop a reproducible mouse model to study blast-induced hearing loss. The tympanic membrane was perforated in all mice after blast exposure and found to heal spontaneously. Micro-computed tomography demonstrated no evidence for middle ear or otic capsule injuries; however, the healed tympanic membrane was thickened. Auditory brainstem response and distortion product otoacoustic emission threshold shifts were found to be correlated with blast intensity. As well, these threshold shifts were larger than those found in control mice that underwent surgical perforation of their tympanic membranes, indicating cochlear trauma. Histological studies one week and three months after the blast demonstrated no disruption or damage to the intra-cochlear membranes. However, there was loss of outer hair cells (OHCs) within the basal turn of the cochlea and decreased spiral ganglion neurons (SGNs) and afferent nerve synapses. Using our mouse model that recapitulates human IED exposure, our results identify that the mechanisms underlying blast-induced hearing loss does not include gross membranous rupture as is commonly believed. Instead, there is both OHC and SGN loss that produce auditory dysfunction

    Bibliography on birds of prey and owls in Slovakia. Part 3. Order Falconiformes, genus Falco

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    Genetic structure of the imperial eagle (Aquila heliaca) population in Slovakia

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    The distribution of the Imperial Eagle (Aquila heliaca) in the Carpathian Basin is not continuous, since western andeastern breeding pairs are separated by 150 km from each other in Slovakia, and 70 km in Hungary. In the present study our aimwas to examine whether this geographical distance has resulted in any genetic separation between the Western and Eastern Slovakbreeding groups. We have used 132 shed feathers and 128 blood samples collected in the fields geographically representingthe whole of the Slovak breeding population, and included all juveniles ringed between 2004 and 2006. After successful DNAextractions we have determined the sex, microsatellite DNA-profiles and mtDNA control region haplotypes of the specimens.Data were integrated in a common Hungarian-Slovak “DNA-fingerprint” database, making identification of the same specimenpossible when recaptured. Based on a subsample of the collected individuals, the genetic structure of the Slovak population wastested using ten microsatellite loci and mtDNA control region haplotypes, and marginally significant genetic differentiation wasfound between western and eastern subpopulations. These results suggest that, in spite of the large dispersal capacity of the species,a relatively small geographic distance can also decrease the exchange rate of individuals between subpopulations. As thisresult involves only samples from the northern part of the breeding area, major conclusions concerning genetic structure and gene flow of Imperial Eagles in the entire Carpathian Basin population cannot be drawn without sampling and analysing the southernsubpopulations in Hungary
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