563 research outputs found

    EDUCATIONAL METHODS USED IN WASHINGTON IRRIGATION DEVELOPMENT

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    Teaching/Communication/Extension/Profession,

    Availability of Ground Water in Wayne County, Iowa

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    Information is presented on the availability and quality of ground water in Wayne County, one of several counties in southern Iowa affected by a shortage of good-quality water. The data indicate that only locally and in limited areas, or only after extensive water-quality treatment, are suitable supplies of ground water available to satisfy the water needs in the county. Bedrock aquifers yield variable amounts of moderately to highly mineralized water. Upper bedrock units at depths of about 200 to 1,000 feet yield up to 50 gpm (gallons per minute) to individual wells; however, the dissolved-solids content of the water ranges from about 2,000 to 5,500 mg/1 (milligrams per liter). Lower bedrock units at depths of 2,500 to 2,800 feet are believed capable of furnishing from 300 to 800 gpm to individual wells, but the dissolved-solids content of the water ranges from 800 to 2,500 mg/1. Surficial aquifers comprising glacial drift and alluvium are estimated to yield up to 45 gpm in some areas; an availability map indicates the areas where water supplies can be developed from these deposits. The chemical quality of water from the surficial aquifers varies considerably; dissolved-solids concentrations range from about 470 mg/1 in the alluvium to over 3,600 mg/1 in the deep (more than 100 feet) glacial drift. Many shallow (100 feet or less) supplies presently in use contain high concentrations of nitrate and chloride, and these concentrations are attributed to localized contamination. Wells in the alluvium and shallow drift that are properly constructed and located are expected to yield satisfactory quality water.https://ir.uiowa.edu/igs_wa/1002/thumbnail.jp

    Modeling the Effects of Hyaluronic Acid Degradation on the Regulation of Human Astrocyte Phenotype Using Multicomponent Interpenetrating Polymer Networks (mIPNs)

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    Hyaluronic acid (HA) is a highly abundant component in the extracellular matrix (ECM) and a fundamental element to the architecture and the physiology of the central nervous system (CNS). Often, HA degradation occurs when an overreactive inflammatory response, derived from tissue trauma or neurodegenerative diseases such as Alzheimer’s, causes the ECM in the CNS to be remodeled. Herein, we studied the effects of HA content as a key regulator of human astrocyte (HAf) reactivity using multicomponent interpenetrating polymer networks (mIPNs) comprised of Collagen I, HA and poly(ethylene glycol) diacrylate. The selected platform facilities the modulation of HA levels independently of matrix rigidity. Total astrocytic processes length, number of endpoints, the expression of the quiescent markers: Aldehyde Dehydrogenase 1 Family Member L1 (ALDH1L1) and Glutamate Aspartate Transporter (GLAST); the reactive markers: Glial Fibrillary Acidic Protein (GFAP) and S100 Calcium-Binding Protein β (S100β); and the inflammatory markers: Inducible Nitric Oxide Synthase (iNOS), Interleukin 1β (IL-1β) and Tumor Necrosis Factor Alpha (TNFα), were assessed. Cumulatively, our results demonstrated that the decrease in HA concentration elicited a reduction in the total length of astrocytic processes and an increase in the expression of HAf reactive and inflammatory markers

    Jet Engine Exhaust Nozzle Flow Effector

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    A jet engine exhaust nozzle flow effector is a chevron formed with a radius of curvature with surfaces of the flow effector being defined and opposing one another. At least one shape memory alloy (SMA) member is embedded in the chevron closer to one of the chevron's opposing surfaces and substantially spanning from at least a portion of the chevron's root to the chevron's tip

    Jet Engine Exhaust Nozzle Flow Effector

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    A jet engine exhaust nozzle flow effector is a chevron formed with a radius of curvature with surfaces of the flow effector being defined and opposing one another. At least one shape memory alloy (SMA) member is embedded in the chevron closer to one of the chevron's opposing surfaces and substantially spanning from at least a portion of the chevron's root to the chevron's tip

    Leveraging the Health and Retirement Study To Advance Palliative Care Research

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    Background: The critical need to expand and develop the palliative care evidence base was recently highlighted by the Journal of Palliative Medicine's series of articles describing the Research Priorities in Geriatric Palliative Care. The Health and Retirement Study (HRS) is uniquely positioned to address many priority areas of palliative care research. This nationally representative, ongoing, longitudinal study collects detailed survey data every 2 years, including demographics, health and functional characteristics, information on family and caregivers, and personal finances, and also conducts a proxy interview after each subject's death. The HRS can also be linked with Medicare claims data and many other data sources, e.g., U.S. Census, Dartmouth Atlas of Health Care. Setting: While the HRS offers innumerable research opportunities, these data are complex and limitations do exist. Therefore, we assembled an interdisciplinary group of investigators using the HRS for palliative care research to identify the key palliative care research gaps that may be amenable to study within the HRS and the strengths and weaknesses of the HRS for each of these topic areas. Conclusion: In this article we present the work of this group as a potential roadmap for investigators contemplating the use of HRS data for palliative care research.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/140117/1/jpm.2013.0648.pd

    Collagen Based Multicomponent Interpenetrating Networks as Promising Scaffolds for 3D Culture of Human Neural Stem Cells, Human Astrocytes, and Human Microglia

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    This work describes for the first time the fabrication and characterization of multicomponent interpenetrating networks composed of collagen I, hyaluronic acid, and poly(ethylene glycol) diacrylate for the 3D culture of human neural stem cells, astrocytes, and microglia. The chemical composition of the scaffolds can be modulated while maintaining values of complex moduli within the range of the mechanical performance of brain tissue (∼6.9 kPa) and having cell viability exceeding 84%. The developed scaffolds are a promising new family of biomaterials that can potentially serve as 3D in vitro models for studying the physiology and physiopathology of the central nervous system
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