905 research outputs found
A soja e a saúde humana.
Soja na prevenção do câncer; Soja na prevenção das doenças cardiovasculares; Soja na prevenção da tensão pré-menstrual e do climatério (menopausa); Soja na prevenção da osteoporose.bitstream/item/57809/1/Documentos-178.pd
Magnetic switching modes for exchange spring systems ErFe2/YFe2/DyFe2/YFe2 with competing anisotropies
The magnetization reversal processes of ½10nm ErFe2=nYFe2=4nm DyFe2=nYFe2" multilayer films with
a (110) growth axis and a variable YFe2 layer thickness n are investigated. The magnetically soft YFe2
compound acts as a separator between the hard rare earth (RE) ErFe2 and DyFe2 compounds, each of
them bearing different temperature dependent magnetic anisotropy properties. Magnetic measurements
of a system with n ¼ 20nm reveal the existence of three switching modes: an independent
switching mode at low temperatures, an ErFe2 spin flop switching mode at medium high temperatures,
and an YFe2 dominated switching mode at high temperatures. The measurements are in qualitative
agreement with the findings of micromagnetic simulations which are used to illustrate the switching
modes. Further simulations for a varied YFe2 layer thickness n ranging from 2 to 40nm are carried out.
Quantitative criteria are defined to classify the reversal behavior, and the resultant switching modes are
laid out in a map with regard to n and the temperature T. A new coupled switching mode emerges above
a threshold temperature for samples with thin YFe2 separation layers as a consequence of the exchange
coupling between the magnetically hard ErFe2 and DyFe2 layers. It reflects the increasing competition of
the two conflicting anisotropies to dominate the magnetic switching states of both RE compounds
under decreasing n
Maternally encoded stem-loop-binding protein is degraded in 2-cell mouse embryos by the co-ordinated activity of two separately regulated pathways
AbstractOocytes accumulate mRNAs and proteins that direct early embryonic development. Although subsequent development requires the timely degradation of these maternal products, little is known of the underlying mechanisms. The stem-loop-binding protein (SLBP), which regulates the stability and translation of mRNAs encoding histones and is synthesized during S-phase and degraded during G2 in somatic cells, accumulates during oogenesis. Maternal SLBP is required for mouse embryos to develop beyond the 2-cell stage, but must be degraded to allow the cell-cycle-regulated expression of somatic cells to be established. We report that the quantity of maternal SLBP changes little following fertilization until 44–52 h post-hCG, corresponding to mid-/late G2 of the 2-cell stage, when it decreases by 75%. Efficient degradation requires two pathways. The first requires activity of cyclin-dependent kinases (cdk) and embryonic transcription, preferentially targets nuclear SLBP, and likely corresponds to the pathway that degrades SLBP at G2 in somatic cells. The second does not require cdk activity or transcription and becomes active at 44–52 h post-hCG independently of cell-cycle progression to mid-/late G2, but is not solely regulated by the time elapsed since hCG injection. Thus, the co-ordinated activity of two separately regulated pathways eliminates maternally encoded SLBP from early mouse embryos
Role of magnetic dopants in the phase diagram of Sm1111 pnictides: The Mn case
The deliberate insertion of magnetic Mn dopants in the Fe sites of the
optimally-doped SmFeAsO0.88-F0.12 iron-based superconductor can modify in a
controlled way its electronic properties. The resulting phase diagram was
investigated across a wide range of manganese contents (x) by means of
muon-spin spectroscopy (muSR), both in zero- and in transverse fields,
respectively, to probe the magnetic and the superconducting order. The pure
superconducting phase (at x < 0.03) is replaced by a crossover region at
intermediate Mn values (0.03 =< x < 0.08), where superconductivity coexists
with static magnetic order. After completely suppressing superconductivity for
x = 0.08, a further increase in Mn content reinforces the natural tendency
towards antiferromagnetic correlations among the magnetic Mn ions. The sharp
drop of Tc and the induced magnetic order in the presence of magnetic
disorder/dopants, such as Mn, are both consistent with a recent theoretical
model of unconventional superconductors [M. Gastiasoro et al., ArXiv
1606.09495], which includes correlation-enhanced RKKY-couplings between the
impurity moments.Comment: 10 pages, 13 figures. Accepted on Physical Review
A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress
Reactive oxygen species (ROS) represent a by-product of metabolism and their excess is toxic for hematopoietic stem and progenitor cells (HSPCs). During embryogenesis, a small number of HSPCs are produced from the hemogenic endothelium, before they colonize a transient organ where they expand, for example the fetal liver in mammals. In this study, we use zebrafish to understand the molecular mechanisms that are important in the caudal hematopoietic tissue (equivalent to the mammalian fetal liver) to promote HSPC expansion. High levels of ROS are deleterious for HSPCs in this niche, however this is rescued by addition of antioxidants. We show that Cx41.8 is important to lower ROS levels in HSPCs. We also demonstrate a new role for ifi30, known to be involved in the immune response. In the hematopoietic niche, Ifi30 can recycle oxidized glutathione to allow HSPCs to dampen their levels of ROS, a role that could be conserved in human fetal liver
Mais saúde em sua vida cozinhando com tofu.
Receita basica de tofu; Salgados: Beringela assada com recheio de tofu; Charutos de repolho com tofu; Frigideira de vegetais e tofu; Torta dos monges budistas; Molho de ervas; Panqueca de tofu com presunto e repolho; Salada com molho de tofu; Salada do "chef" com tofu; Tofu a italiana; Tofu com brotos de feijao; Tofu frito com recheio de queijo; Tofu de cinco cores; Tofu com vegetais e ovos; Tofu oito tesouros; Doces: Manjar de tofu e abacaxi; Pudim de tofu; Sufle de tofu; Torta de tofu.bitstream/CNPSO/2629/1/circTec29.pd
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