Protein Sources for Growing Beef Steers Fed with a Diet Based on Corn Silage

This study was conducted to determine the effect of different protein sources in growing beef cattle (25 Aberdeen Angus steers) fed with a corn silage based diet on daily live weight gain (DLWG), dry matter intake (DMI) and feed conversion (FC). Five treatments with different supplies of crude, degradable and metabolizable protein (MP) were used. The treatments were formulated with different protein sources to provide different rate and extents of protein degradation, as follow: a negative control (T0) without protein supplements and below animal requirements, urea (T1), soybean meal (T2), whole cotton seed (T3) and a positive control (T4), which include a mixture of protein sources in excess of animal requirements. The treatments were planned to be isoenergetics (2.63 Mcal ME kg -1 DM) and also T1, T2 and T3 were isoprotein. The data were analyzed statistically by ANOVA. The DGWG were significant different 730, 869, 1006, 946 and 979 g.day-1 for T0, T1, T2, T3, and T4 respectively. The main differences in DMI were obtained in the isoprotein treatments. Exceeding the animal requirements of metabolizable protein to achieve a suitable nitrogenous supply to rumen did not produce any improvement in the animal performance. The supply of nitrogenous in diets based on corn silage improves the DLWG and FC. This effect was higher with the use of true protein

Resistencia a la compresión de Biodentine®: mezcla manual vs. Mecánica

INTRODUCCIÓN: La incorporación de innovaciones tecnológicas en determinados materiales dentales, especialmente aquellos que requieren de aparatología específica para su uso y/o cuya pre-dosificación implica el descarte de una porción de su contenido, está condicionada por la relación costo-beneficio del producto. Según las instrucciones del fabricante, las cápsulas del silicato tricálcico Biodentine® (Septodont) deben activarse mediante el uso de mezcladores mecánicos luego de adicionar las proporciones exactas del líquido ad-hoc, utilizando la totalidad de cada cápsula de polvo y su respectiva ampolla del líquido, con un excedente de material considerable, según su indicación. Si bien es posible realizar la mezcla del cemento en forma manual prescindiendo de un amalgamador, una modificación en las recomendaciones del fabricante podría alterar las propiedades del material. OBJETIVO: Determinar si existen diferencias en la resistencia compresiva de Biodentine® según el método de mezcla utilizado: con activación mecánica y con mezcla manual. MATERIALES Y METODOS: Se confeccionaron probetas cilíndricas de 6 mm de alto por 4 mm de diámetro (n=6) para los dos grupos de estudio A) Biodentine® / Mezcla manual y B) Biodentine® / Mezcla mecánica. Las muestras fueron sometidas a la aplicación de una fuerza continua en máquina universal de ensayos Digimess RS-8000-5 a una velocidad de carrera de 1 mm/min hasta su ruptura. Se compararon los valores obtenidos entre los grupos mediante test de Student, determinando diferencias significativas para valores de p>0,05. RESULTADOS: Los valores medios obtenidos y su desviación estándar fueron A) 52.6 (16.3) MPa y B) 65.7 (30.6) MPa respectivamente. La distribución de valores de resistencia a la compresión según el grupo de estudio fue levemente superior en el grupo B, aunque las diferencias no fueron significativas (p=3,77). CONCLUSIONES: La mezcla manual no disminuye significativamente la resistencia a la compresión de Biodentine® en comparación al cemento mezclado mecánicamente

Endoscopic transnasal transseptal pituitary surgery

International audiencePituitary surgery is performed via a transsphenoidal approach in the vast majority of cases according to various methods that have changed over the years. A microscopic transseptal approach via a sublabial mucosal incision or a nasal mucosal incision has also been extensively used. An endoscopic transnasal approach was first described in the 1990's, followed by the concept of a microscopic transseptal approach and an endoscopic strictly endonasal approach. We use an entirely endoscopic transseptal transsphenoidal approach via an incision in the nasal mucosa for both access and tumour resection. This procedure has a number of advantages: strictly midline approach to the sella turcica, large operative field, no interference between instruments and a low rate of nasal complications

Les méningiomes : mise au point sur les connaissances actuelles

International audienceMeningiomas are the most frequent among intracranial tumors, and represent more than 30% of primitive central nervous system neoplasms. Arising from the meninges, they are generally benign lesions and can be treated by either radio-clinical follow-up or surgical resection with excellent outcome. However, more than 20% of meningiomas harbor atypical or malignant features and represent challenges for both prognostic evaluation and therapeutic strategy. The discovery of the genetic and epigenetic landscapes of meningiomas enabled the identification of new prognostic markers and potential therapeutic targets for refractory meningiomas. This review summarizes current epidemiology, histological and molecular characteristics, diagnosis and treatments for meningiomas, and highlights the close relationship between the development of meningiomas and hormonal intake, as illustrated by recent recommendations of the "Agence Nationale de Securité du Medicament", the French national drug safety agency.Les méningiomes sont les tumeurs intracrâniennes les plus fréquentes, représentant plus d’un tiers des tumeurs primitives du système nerveux central. Développés au dépens des méninges, ils sont généralement histologiquement bénins et bénéficient d’un suivi radioclinique par IRM ou d’un traitement par exérèse chirurgicale avec de bons résultats. Cependant, 20 % d’entre eux se présentent sous la forme de tumeurs plus agressives représentant un défi à la fois pour l’évaluation du pronostic et pour le choix des traitements. Les avancées dans la caractérisation moléculaire et génétique des méningiomes ont permis d’appréhender de nouveaux facteurs pronostiques et de découvrir de potentielles cibles pour des traitements ciblés dans les formes réfractaires à la chirurgie et à la radiothérapie. Cette mise au point synthétise les connaissances épidémiologiques, moléculaires et histologiques, et les modalités de diagnostic et de traitement des méningiomes, ainsi que le lien entre les progestatifs et les méningiomes à la lumière des recommandations récentes de l’Agence nationale de sécurité du médicament

Is hospital information system relevant to detect surgical site infection? Findings from a prospective surveillance study in posterior instrumented spinal surgery

International audienceOBJECT:Spinal instrumentation has a high rate of surgical site infection (SSI), but results greatly vary depending on surveillance methodology, surgical procedures, or quality of follow-up. Our aim was to study true incidence of SSI in spinal surgery by significant data collection, and to compare it with the results obtained through the hospital information system.METHODS:This work is a single center prospective cohort study that included all patients consecutively operated on for spinal instrumentation by posterior approach over a six-month period regardless the etiology. For all patients, a "high definition" prospective method of surveillance was performed by the infection control (IC) department during at least 12 months after surgery. Results were then compared with findings from automatic surveillance though the hospital information system (HIS).RESULTS:One hundred and fifty-four patients were included. We found no hardly difference between "high definition" and automatic surveillance through the HIS, even if HIS tended to under-estimate the infection rate: rate of surgical site infection was 2.60% and gross SSI incidence rate via the hospital information system was 1.95%. Smoking and alcohol consumption were significantly related to a SSI.CONCLUSION:Our SSI rates to reflect the true incidence of infectious complications in posterior instrumented adult spinal surgery in our hospital and these results were consistent with the lower levels of published infection rate. In-house surveillance by surgeons only is insufficiently sensitive. Further studies with more patients and a longer inclusion time are needed to conclude if SSI case detection through the HIS could be a relevant and effective alternative method

Pituitary metastasis of malignant melanoma misdiagnosed as pituitary adenoma: A case report and systematic review of the literature

International audienceWe report a case of malignant melanoma revealed by a metastasis to the pituitary gland. The tumor was misdiagnosed as a pituitary adenoma and aggressive transsphenoidal surgery was complicated by a cerebrospinal fluid fistula. Nine weeks later, the patient presented multiple leptomeningeal and brain metastases spreading from the sellar region. Regarding these observations, we conducted a systematic review of the literature in order to investigate clinicoradiological features that should lead clinicians to suspect pituitary metastasis and how it should impact the surgical management