Dirty Paper Arbitrarily Varying Channel with a State-Aware Adversary

In this paper, we take an arbitrarily varying channel (AVC) approach to examine the problem of writing on a dirty paper in the presence of an adversary. We consider an additive white Gaussian noise (AWGN) channel with an additive white Gaussian state, where the state is known non-causally to the encoder and the adversary, but not the decoder. We determine the randomized coding capacity of this AVC under the maximal probability of error criterion. Interestingly, it is shown that the jamming adversary disregards the state knowledge to choose a white Gaussian channel input which is independent of the state

Correlated Jamming in a Joint Source Channel Communication System

We study correlated jamming in joint source-channel communication systems. An i.i.d. source is to be communicated over a memoryless channel in the presence of a correlated jammer with non-causal knowledge of user transmission. This user-jammer interaction is modeled as a zero sum game. A set of conditions on the source and the channel is provided for the existence of a Nash equilibrium for this game, where the user strategy is uncoded transmission and the jammer strategy is i.i.d jamming. This generalizes a well-known example of uncoded communication of a Gaussian sources over Gaussian channels with additive jamming. Another example, of a Binary Symmetric source over a Binary Symmetric channel with jamming, is provided as a validation of this result

Soft Electromagnetic Radiations from Relativistic Heavy Ion Collisions

The production of low mass dileptons and soft photons from thermalized Quark Gluon Plasma (QGP) and hadronic matter in relativistic heavy ion collisions is evaluated. A boost invariant longitudinal and cylindrically symmetric transverse expansion of the systems created in central collision of lead nuclei at CERN SPS, BNL RHIC, and CERN LHC, and undergoing a first order phase transition to hadronic matter is considered. A large production of low mass (M< 0.3 GeV) dileptons, and soft photons (p_T< 0.4 GeV) is seen to emanate from the bremsstrahlung of quarks and pions. We find an increase by a factor of 2--4 in the low mass dilepton and soft photon yield as we move from SPS to RHIC energies, and an increase by an order of magnitude as we move from SPS to LHC energies. Most of the soft radiations are found to originate from pion driven processes at SPS and RHIC energies, while at the LHC energies the quark and the pion driven processes contribute by a similar amount. The study of the transverse mass distribution is seen to provide interesting details of the evolution. We also find a unique universal behaviour for the ratio of M^2 weighted transverse mass distribution for M= 0.1 GeV to that for M= 0.2 and 0.3 GeV, as a function of M_T, for SPS, RHIC, and LHC energies, in the absence of transverse expansion of the system. A deviation from this universal behaviour is seen as a clear indication of the flow.Comment: Revtex fil

An Attenuated Zika Virus Encoding Non-Glycosylated Envelope (E) and Non-Structural Protein 1 (NS1) Confers Complete Protection against Lethal Challenge in a Mouse Model

Zika virus (ZIKV), a mosquito-transmitted flavivirus, emerged in the last decade causing serious human diseases, including congenital microcephaly in newborns and Guillain-Barré syndrome in adults. Although many vaccine platforms are at various stages of development, no licensed vaccines are currently available. Previously, we described a mutant MR766 ZIKV (m2MR) bearing an E protein mutation (N154A) that prevented its glycosylation, resulting in attenuation and defective neuroinvasion. To further attenuate m2MR for its potential use as a live viral vaccine, we incorporated additional mutations into m2MR by substituting the asparagine residues in the glycosylation sites (N130 and N207) of NS1 with alanine residues. Examination of pathogenic properties revealed that the virus (m5MR) carrying mutations in E (N154A) and NS1 (N130A and N207A) was fully attenuated with no disease signs in infected mice, inducing high levels of humoral and cell-mediated immune responses, and protecting mice from subsequent lethal virus challenge. Furthermore, passive transfer of sera from m5MR-infected mice into naïve animals resulted in complete protection from lethal challenge. The immune sera from m5MR-infected animals neutralized both African and Asian lineage viruses equally well, suggesting that m5MR virus could be developed as a potentially broad live virus vaccine candidate

An Attenuated Zika Virus Encoding Non-Glycosylated Envelope (E) and Non-Structural Protein 1 (NS1) Confers Complete Protection against Lethal Challenge in a Mouse Model

Zika virus (ZIKV), a mosquito-transmitted flavivirus, emerged in the last decade causing serious human diseases, including congenital microcephaly in newborns and Guillain-Barré syndrome in adults. Although many vaccine platforms are at various stages of development, no licensed vaccines are currently available. Previously, we described a mutant MR766 ZIKV (m2MR) bearing an E protein mutation (N154A) that prevented its glycosylation, resulting in attenuation and defective neuroinvasion. To further attenuate m2MR for its potential use as a live viral vaccine, we incorporated additional mutations into m2MR by substituting the asparagine residues in the glycosylation sites (N130 and N207) of NS1 with alanine residues. Examination of pathogenic properties revealed that the virus (m5MR) carrying mutations in E (N154A) and NS1 (N130A and N207A) was fully attenuated with no disease signs in infected mice, inducing high levels of humoral and cell-mediated immune responses, and protecting mice from subsequent lethal virus challenge. Furthermore, passive transfer of sera from m5MR-infected mice into naïve animals resulted in complete protection from lethal challenge. The immune sera from m5MR-infected animals neutralized both African and Asian lineage viruses equally well, suggesting that m5MR virus could be developed as a potentially broad live virus vaccine candidate

Radiation of single photons from Pb+PbPb+Pb collisions at the CERN SPS and quark hadron phase transition

The production of single photons in $Pb+Pb$ collisions at the CERN SPS as measured by the WA98 experiment is analysed. A quark gluon plasma is assumed to be formed initially, which expands, cools, hadronizes, and undergoes freeze-out. A rich hadronic equation of state is used and the transverse expansion of the interacting system is taken into account. The recent estimates of photon production in quark-matter (at two loop level) along with the dominant reactions in the hadronic matter leading to photons are used. About 50% of the single photons are seen to have a thermal origin. An addition of the thermal and prompt photons is seen to provide a very good description of the data. Most of the thermal photons having large transverse momenta arise from the quark-matter, which contributes dominantly through the mechanism of annihilation of quarks with scattering, and which in turn is possible only in a hot and dense plasma of quarks and gluons. The results thus confirm the formation of quark gluon plasma and the existence of this mechanism of the production of single photons.Comment: 6 pages including 3 figures. Corrected 2-loop rates for photons are use

Mitochondrial haplogroup N1a phylogeography, with implication to the origin of European farmers

<p>Abstract</p> <p>Background</p> <p>Tracing the genetic origin of central European farmer N1a lineages can provide a unique opportunity to assess the patterns of the farming technology spread into central Europe in the human prehistory. Here, we have chosen twelve N1a samples from modern populations which are most similar with the farmer N1a types and performed the complete mitochondrial DNA genome sequencing analysis. To assess the genetic and phylogeographic relationship, we performed a detailed survey of modern published N1a types from Eurasian and African populations.</p> <p>Results</p> <p>The geographic origin and expansion of farmer lineages related N1a subclades have been deduced from combined analysis of 19 complete sequences with 166 N1a haplotypes. The phylogeographic analysis revealed that the central European farmer lineages have originated from different sources: from eastern Europe, local central Europe, and from the Near East via southern Europe.</p> <p>Conclusions</p> <p>The results obtained emphasize that the arrival of central European farmer lineages did not occur via a single demic diffusion event from the Near East at the onset of the Neolithic spread of agriculture into Europe. Indeed these results indicate that the Neolithic transition process was more complex in central Europe and possibly the farmer N1a lineages were a result of a 'leapfrog' colonization process.</p

The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis

Background: The development of digital technologies and the evolution of open innovation approaches have enabled the creation of diverse virtual organizations and enterprises coordinating their activities primarily online. The open innovation platform titled "International Natural Product Sciences Taskforce" (INPST) was established in 2018, to bring together in collaborative environment individuals and organizations interested in natural product scientific research, and to empower their interactions by using digital communication tools. Methods: In this work, we present a general overview of INPST activities and showcase the specific use of Twitter as a powerful networking tool that was used to host a one-week "2021 INPST Twitter Networking Event" (spanning from 31st May 2021 to 6th June 2021) based on the application of the Twitter hashtag #INPST. Results and Conclusion: The use of this hashtag during the networking event period was analyzed with Symplur Signals (https://www.symplur.com/), revealing a total of 6,036 tweets, shared by 686 users, which generated a total of 65,004,773 impressions (views of the respective tweets). This networking event's achieved high visibility and participation rate showcases a convincing example of how this social media platform can be used as a highly effective tool to host virtual Twitter-based international biomedical research events