2,640 research outputs found

    Do syllables play a role in German speech perception? Behavioral and electrophysiological data from primed lexical decision.

    Get PDF
    Copyright © 2015 Bien, Bölte and Zwitserlood. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.We investigated the role of the syllable during speech processing in German, in an auditory-auditory fragment priming study with lexical decision and simultaneous EEG registration. Spoken fragment primes either shared segments (related) with the spoken targets or not (unrelated), and this segmental overlap either corresponded to the first syllable of the target (e.g., /teis/ - /teisti/), or not (e.g., /teis/ - /teistləs/). Similar prime conditions applied for word and pseudoword targets. Lexical decision latencies revealed facilitation due to related fragments that corresponded to the first syllable of the target (/teis/ - /teisti/). Despite segmental overlap, there were no positive effects for related fragments that mismatched the first syllable. No facilitation was observed for pseudowords. The EEG analyses showed a consistent effect of relatedness, independent of syllabic match, from 200 to 500 ms, including the P350 and N400 windows. Moreover, this held for words and pseudowords that differed however in the N400 window. The only specific effect of syllabic match for related prime-target pairs was observed in the time window from 200 to 300 ms. We discuss the nature and potential origin of these effects, and their relevance for speech processing and lexical access

    Strong rules for discarding predictors in lasso-type problems

    Full text link
    We consider rules for discarding predictors in lasso regression and related problems, for computational efficiency. El Ghaoui et al (2010) propose "SAFE" rules that guarantee that a coefficient will be zero in the solution, based on the inner products of each predictor with the outcome. In this paper we propose strong rules that are not foolproof but rarely fail in practice. These can be complemented with simple checks of the Karush- Kuhn-Tucker (KKT) conditions to provide safe rules that offer substantial speed and space savings in a variety of statistical convex optimization problems.Comment:

    Acute Kidney Injury in COVID-19: secondary analysis of prospective data from the EthICAL study

    Get PDF
    Statistical Analysis Plan – This secondary analysis of the EthICAL study will focus on the incidence, risk factors and outcomes associated with AKI within COVID-19 patients admitted to five acute hospitals in East London. We will also examine follow-up data to investigate what proportion of COVID-19 patients who developed an AKI never recovered their renal function and progressed to chronic kidney disease (CKD)

    Dissecting gene expression at the blood-brain barrier

    Get PDF
    The availability of genome-wide expression data for the blood-brain barrier is an invaluable resource that has recently enabled the discovery of several genes and pathways involved in the development and maintenance of the blood-brain barrier, particularly in rodent models. The broad distribution of published datasets represents a viable starting point for the molecular dissection of the blood-brain barrier and will further direct the discovery of novel mechanisms of blood-brain barrier formation and function. Technical advances in purifying brain endothelial cells, the key cell that forms the critical barrier, have allowed for greater specificity in gene expression comparisons with other central nervous system cell types, and more systematic characterizations of the molecular composition of the blood-brain barrier. Nevertheless, our understanding of how the blood-brain barrier changes during aging and disease is underrepresented. Blood-brain barrier datasets from a wider range of experimental paradigms and species, including invertebrates and primates, would be invaluable for investigating the function and evolution of the blood-brain barrier. Newer technologies in gene expression profiling, such as RNA-sequencing, now allow for finer resolution of transcriptomic changes, including isoform specificity and RNA-editing. As our field continues to utilize more advanced expression profiling in its ongoing efforts to elucidate the blood-brain barrier, including in disease and drug delivery, we will continue to see rapid advances in our understanding of the molecular mediators of barrier biology. We predict that the recently published datasets, combined with forthcoming genomic and proteomic blood-brain barrier datasets, will continue to fuel the molecular genetic revolution of blood-brain barrier biology

    Beliefs, points of view, and multiple environments

    Get PDF

    Wer gehört heute zur Familie?

    Full text link

    Exploring social constructions of followership: A qualitative study

    Get PDF
    This study adopts a qualitative approach to deconstruct the meaning of followership. Interviews were conducted with employees in various industries to examine how individuals socially construct their roles as followers and to explore followership schemas and contextual influences that relate to these constructions. Results suggest that while some individuals socially construct definitions around passivity, deference and obedience, others emphasize the importance of constructively questioning and challenging their leaders. With regard to personal qualities that are thought to make followers effective, major themes such as obedience, expressing opinions, and taking initiative were found to be most disparate across different groups of followers. Results also revealed that contextual factors may affect both followership constructions and behavior in the follower role. These findings have important implications regarding a need to examine the construct of followership in leadership research, as well as raise interesting possibilities for advancing an “expanded” view of leadership in organizations

    Reciprocity in Manager-Subordinate Relationships: Components, Configurations, and Outcomes

    Get PDF
    The EU, which produces about 80 million tons of vegetable protein (half of which is fodder) imports about 15 million tons of non-processed and coproducts of the food industry not usable by humans. About 87 % of the domestic consumption of vegetal proteins is for animal feed and allows the production of 11 million tons of animal protein for milk, meat and eggs. The highly developed compound feed industry provides 67 % of the protein excluding fodder and shows a strong diversification in its raw materials consumed. Globally, soybeans, whose imports have declined significantly over the past 10 years, account for only 18 % of the plant proteins used by animals. The EU's rate in world imports has decreased from 60 % in the early 1970s to less than 19 % today. France consumes 12 million tons of animal protein feed and has many similarities with the EU, but there is a key difference: it is a net exporter of 1.5 million tons of vegetal protein mainly as cereals. Whereas the EU is a net importer of "agricultural areas", France can export both animal and plant proteins thanks to its large agricultural areas and the diversity of its agricultures (with the Great West being specialized in animal production and other regions that benefit from high yields of plants)
    corecore