85 research outputs found

    Acute physical exercise improves shifting in adolescents at school: evidence for a dopaminergic contribution

    Get PDF
    The executive function of shifting between mental sets demands cognitive flexibility. Based on evidence that physical exercise fostered cognition, we tested whether acute physical exercise can improve shifting in an unselected sample of adolescents. Genetic polymorphisms were analyzed to gain more insight into possibly contributing neurophysiological processes. We examined 297 students aged between 13 and 17 years in their schools. Physical exercise was manipulated by an intense incremental exercise condition using bicycle ergometers and a control condition which involved watching an infotainment cartoon while sitting calm. The order of conditions was counterbalanced between participants. Shifting was assessed by a switching task after both conditions. Acute intense physical exercise significantly improved shifting as indicated by reduced switch costs. Exercise-induced performance gains in switch costs were predicted by a single nucleotide polymorphism (SNP) targeting the Dopamine Transporter (DAT1/SLCA6A3) gene suggesting that the brain dopamine system contributed to the effect. The results demonstrate the potential of acute physical exercise to improve cognitive flexibility in adolescents. The field conditions of the present approach suggest applications in schools

    The ‘integrative approach’ and labour regulation and Indonesia: prospects and challenges

    Get PDF
    In contrast to theories of regulation which bypass the state and cede regulatory authority to private regimes, the scholar Kevin Kolben makes a cogent argument for the state to be brought back to centre stage in labour regulation, but envisages that private actors can develop and strengthen its capacity. This article considers the utility of what he terms an integrative approach for Indonesia. In line with what the approach advocates, the article examines the relationships between private actors and the state and considers the extent to which the former can communicate, interact with and incentivise the latter in ways which strengthen its regulatory capacity. Several challenges are identified. Finally, the potential of the Better Work Programme in Indonesia to further the goals of the approach is assessed

    Thrombogenesis: An epitaxial phenomena. I

    Full text link
    A semiempirical epitaxial model has been derived which correlates and interrelates the surface free energy, ultrastructural morphology, surface charge, surface chemistry, and surface molecular motions of a model triblock copolymer to thrombogenesis. This paper addresses the aspect of: (1) ultrastructure order versus disorder, (2) primary and secondary molecular motions, (3) surface and side chain chemistry, (4) thrombogenesis, and (5) the derived epitaxial model based on the above observations. This model can be extrapolated to include and predict the relative thrombogenic responses of various crystalline and semicrystalline polymeric substrates, i.e., aliphatic polyolefins, polyurethanes, and polypeptides.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/37995/1/820150210_ftp.pd
    • 

    corecore