54,721 research outputs found
International Committee on Mental Health in Cystic Fibrosis: Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus statements for screening and treating depression and anxiety
Studies measuring psychological distress in individuals with cystic fibrosis (CF) have found high rates of both depression and anxiety. Psychological symptoms in both individuals with CF and parent caregivers have been associated with decreased lung function, lower body mass index, worse adherence, worse health-related quality of life, more frequent hospitalisations and increased healthcare costs. To identify and treat depression and anxiety in CF, the CF Foundation and the European CF Society invited a panel of experts, including physicians, psychologists, psychiatrists, nurses, social workers, a pharmacist, parents and an individual with CF, to develop consensus recommendations for clinical care. Over 18 months, this 22-member committee was divided into four workgroups: Screening; Psychological Interventions; Pharmacological Treatments and
Implementation and Future Research, and used the Population, Intervention, Comparison, Outcome methodology to develop questions for literature search and review. Searches were conducted in PubMed, PsychINFO, ScienceDirect, Google Scholar, Psychiatry
online and ABDATA by a methodologist at Dartmouth. The committee reviewed 344 articles, drafted statements and set an 80% acceptance for each recommendation statement as a consensus threshold prior to an anonymous voting process. Fifteen guideline recommendation statements for screening and treatment of depression and anxiety in individuals with CF and parent caregivers were finalised by vote. As these recommendations are implemented in CF centres internationally, the process of dissemination, implementation and resource provision should be closely monitored to assess barriers and concerns, validity and use
An Introduction to Superconducting Qubits and Circuit Quantum Electrodynamics
A subset of the concepts of circuit quantum electrodynamics are reviewed as a
reference to the Axion Dark Matter Experiment (ADMX) community as part of the
proceedings of the 2nd Workshop on Microwave Cavities and Detectors for Axion
Research. The classical Lagrangians and Hamiltonians for an LC circuit are
discussed along with black box circuit quantization methods for a weakly
anharmonic qubit coupled to a resonator or cavity
Trust economics feasibility study
We believe that enterprises and other organisations currently lack sophisticated methods and tools to determine if and how IT changes should be introduced in an organisation, such that objective, measurable goals are met. This is especially true when dealing with security-related IT decisions. We report on a feasibility study, Trust Economics, conducted to demonstrate that such methodology can be developed. Assuming a deep understanding of the IT involved, the main components of our trust economics approach are: (i) assess the economic or financial impact of IT security solutions; (ii) determine how humans interact with or respond to IT security solutions; (iii) based on above, use probabilistic and stochastic modelling tools to analyse the consequences of IT security decisions. In the feasibility study we apply the trust economics methodology to address how enterprises should protect themselves against accidental or malicious misuse of USB memory sticks, an acute problem in many industries
Angle-dependence of quantum oscillations in YBa2Cu3O6.59 shows free spin behaviour of quasiparticles
Measurements of quantum oscillations in the cuprate superconductors afford a
new opportunity to assess the extent to which the electronic properties of
these materials yield to a description rooted in Fermi liquid theory. However,
such an analysis is hampered by the small number of oscillatory periods
observed. Here we employ a genetic algorithm to globally model the field,
angular, and temperature dependence of the quantum oscillations observed in the
resistivity of YBa2Cu3O6.59. This approach successfully fits an entire data set
to a Fermi surface comprised of two small, quasi-2-dimensional cylinders. A key
feature of the data is the first identification of the effect of Zeeman
splitting, which separates spin-up and spin-down contributions, indicating that
the quasiparticles in the cuprates behave as nearly free spins, constraining
the source of the Fermi surface reconstruction to something other than a
conventional spin density wave with moments parallel to the CuO2 planes.Comment: 8 pages, 4 figure
Risk of thromboembolism in patients developing critical illness-associated atrial fibrillation
This is the author accepted manuscript. The final version is available from the Royal College of Physicians via the DOI in this record.Although common, the long-term significance of developing atrial fibrillation (AF) during a period of
critical illness is unclear. We undertook a retrospective cohort analysis to assess the rate of
thromboembolism (TE) in patients developing atrial fibrillation de novo during admission to our
intensive care unit. 1955 patients were followed up (maximum follow-up 1276 days) for the
occurrence of TE, of which 220 (11.3%) had developed AF or atrial flutter during their critical care
admission. There were 11 TE events among the patients with new AF (0.053 events per patientyear),
compared with 18 in the non-AF group (0.0059 events per patient-year). The unadjusted
hazard ratio for TE in patients developing new AF compared with those not developing AF was 8.09
(95% CI 3.08 – 17.19, p<0.001). In patients admitted to critical care, the development of AF appears
to be associated with a significantly increased risk of subsequent thromboembolism
A Spectral Line Survey from 138.3 to 150.7 GHZ toward Orion-KL
We present the results of a spectral line survey from 138.3 to 150.7 GHz
toward Orion-KL. The observations were made using the 14 m radio telescope of
Taeduk Radio Astronomy Observatory. Typical system temperatures were between
500 and 700 K, with the sensitivity between K in units of .
A total of 149 line spectra are detected in this survey. Fifty lines have
been previously reported, however we find 99 new detections. Among these new
lines, 32 are `unidentified', while 67 are from molecular transitions with
known identifications. There is no detection of H or He recombination lines.
The identified spectra are from a total of 16 molecular species and their
isotopic variants. In the range from 138.3 to 150.7 GHz, the strongest spectral
line is the J=3-2 transition of CS molecule, followed by transitions of the
, , , and . Spectral lines from
the large organic molecules such as , , , and are prominent; with 80 % of the
identified lines arising from transitions of these molecules. The rotational
temperatures and column densities are derived using the standard rotation
diagram analysis for (), , and with and . These estimates are fairly comparable to the values for the
same molecule in other frequency regions by other studies.Comment: 10 figures, 2 tex files for a manuscript and tables, accepted to Ap
Prevalence of Illicit Use and Abuse of Prescription Stimulants, Alcohol, and Other Drugs Among College Students: Relationship with Age at Initiation of Prescription Stimulants
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90112/1/phco.27.5.666.pd
Treatment compliance and effectiveness of a cognitive behavioural intervention for low back pain : a complier average causal effect approach to the BeST data set
Background:
Group cognitive behavioural intervention (CBI) is effective in reducing low-back pain and disability in comparison to advice in primary care. The aim of this analysis was to investigate the impact of compliance on estimates of treatment effect and to identify factors associated with compliance.
Methods:
In this multicentre trial, 701 adults with troublesome sub-acute or chronic low-back pain were recruited from 56 general practices. Participants were randomised to advice (control n = 233) or advice plus CBI (n = 468). Compliance was specified a priori as attending a minimum of three group sessions and the individual assessment. We estimated the complier average causal effect (CACE) of treatment.
Results:
Comparison of the CACE estimate of the mean treatment difference to the intention-to-treat (ITT) estimate at 12 months showed a greater benefit of CBI amongst participants compliant with treatment on the Roland Morris Questionnaire (CACE: 1.6 points, 95% CI 0.51 to 2.74; ITT: 1.3 points, 95% CI 0.55 to 2.07), the Modified Von Korff disability score (CACE: 12.1 points, 95% CI 6.07 to 18.17; ITT: 8.6 points, 95% CI 4.58 to 12.64) and the Modified von Korff pain score (CACE: 10.4 points, 95% CI 4.64 to 16.10; ITT: 7.0 points, 95% CI 3.26 to 10.74). People who were non-compliant were younger and had higher pain scores at randomisation.
Conclusions:
Treatment compliance is important in the effectiveness of group CBI. Younger people and those with more pain are at greater risk of non-compliance
Representations of Double Affine Lie algebras
We study representations of the double affine Lie algebra associated to a
simple Lie algebra. We construct a family of indecomposable integrable
representations and identify their irreducible quotients. We also give a
condition for the indecomposable modules to be irreducible, this is analogous
to a result in the representation theory of quantum affine algebras. Finally,
in the last section of the paper, we show, by using the notion of fusion
product, that our modules are generically reducible
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