SELNET clinical practice guidelines for bone sarcoma

Bone sarcoma; Clinical guidelines; Latin-America contextSarcoma óseo; Guías clínicas; Contexto latinoamericanoSarcoma ossi; Guies clíniques; Context llatinoamericàBone sarcoma are infrequent diseases, representing < 0.2% of all adult neoplasms. A multidisciplinary management within reference centers for sarcoma, with discussion of the diagnostic and therapeutic strategies within an expert multidisciplinary tumour board, is essential for these patients, given its heterogeneity and low frequency. This approach leads to an improvement in patient’s outcome, as demonstrated in several studies. The Sarcoma European Latin-American Network (SELNET), aims to improve clinical outcome in sarcoma care, with a special focus in Latin-American countries. These Clinical Practice Guidelines (CPG) have been developed and agreed by a multidisciplinary expert group (including medical and radiation oncologist, surgical oncologist, orthopaedic surgeons, radiologist, pathologist, molecular biologist and representatives of patients advocacy groups) of the SELNET consortium, and are conceived to provide the standard approach to diagnosis, treatment and follow-up of bone sarcoma patients in the Latin-American context.The authors would like to thank the SELNET project, which has received funding from the EU Horizon 2020 research and innovation programme (grant number 825806)

Age- and sex-specific normative values for muscle mass parameters in 18,625 Brazilian adults

BackgroundThe present study aimed to provide age- and sex-specific normative values for muscle mass parameters in Brazilian adults.MethodsData pertaining to Brazilian adults (18+ years) who attended a nutritional clinical between January 2018 and July 2022 were analyzed. Muscle mass parameters were assessed using a bioimpedance digital scale (InBody 230, GBC BioMed NZ). Assessments were conducted under standard conditions, with participants refraining from physical exercise for 96 h and from eating or drinking (including water) for 8 h before evaluations.ResultsA total of 18,625 Brazilian adults were analyzed. Normative values for absolute and relative (height, m2) muscle mass and appendicular muscle mass (ASM) were calculated. In addition, specific age-related changes in muscle mass parameters were observed. In women, muscle mass peaked between the ages of 40–49 before gradually declining at an average rate of 5.7% per decade from the sixth decade of life onwards. ASM reached its peak earlier, during the third decade of life, and started to decline later, from 50 to 59 years. In contrast, absolute and ASM peaked at 40–49 years and declined from the sixth decade of life in men. Both sexes displayed a slightly greater decline in ASM than in muscle mass (13 vs. 12%).ConclusionsThe present study provides normative values for absolute and relative muscle mass and ASM in Brazilian adults. Furthermore, important specific age-related changes in muscle mass parameters were observed. These data have public health implications and might serve as a reference tool to guide health professionals

Casos confirmados de Esquistossomose no Pará no período de 2007 a 2017 / Confirmed cases of Schistosomiasis in Pará in the period 2007 to 2017

Introdução: A esquistossomose é uma doença crônica causada pelos parasitas multicelulares platelmintos do gênero Schistosoma. A esquistossomose possui o homem como hospedeiro definitivo, modificações ambientais e condições inadequadas de saneamento básico são as principais responsáveis pelo aumento do número de transmissores e de seus focos de transmissão. Sendo uma doença relacionada fortemente com as condições socioeconômicas da população.Objetivo: Analisar os casos confirmados de Esquistossomose de 2007 a 2017 no Pará.Método: Trata-se de um estudo descritivo, feito com base em dados recolhidos por meio de fichas de notificação compulsórias do SINAN presentes no DATASUS. Foram recolhidas informações condizentes com o ano da notificação, cidades e escolaridade durante o período de 2007 a 2017.Resultados: Foram encontrados 174 casos notificados, sendo que a maioria ocorreu no ano de 2009 (22,9%), enquanto que minoria ocorreu no ano de 2007 (2,2%). Além disso a cidade mais afetada foi a cidade de Altamira (23,5%), porém acredita-se que possam existir subnotificações em outras cidades do estado. No que diz respeito a escolaridade, os mais afetados foram pacientes com escolaridade da 1ª à 4ª série incompleta do ensino fundamental (20,6%), seguidos pelos analfabetos (17,8%).Conclusão: Foi visto um acréscimo aos casos de notificação compulsória de Esquistossomose no Pará em um comparativo dos anos de 2007 e 2017. No entanto, acredita-se que ainda há muitas subnotificações, principalmente nas cidades mais interioranas.

SELNET clinical practice guidelines for bone sarcoma

Bone sarcoma are infrequent diseases, representing < 0.2% of all adult neoplasms. A multidisciplinary management within reference centers for sarcoma, with discussion of the diagnostic and therapeutic strategies within an expert multidisciplinary tumour board, is essential for these patients, given its heterogeneity and low frequency. This approach leads to an improvement in patient's outcome, as demonstrated in several studies. The Sarcoma European Latin-American Network (SELNET), aims to improve clinical outcome in sarcoma care, with a special focus in Latin-American countries. These Clinical Practice Guidelines (CPG) have been developed and agreed by a multidisciplinary expert group (including medical and radiation oncologist, surgical oncologist, orthopaedic surgeons, radiologist, pathologist, molecular biologist and representatives of patients advocacy groups) of the SELNET consortium, and are conceived to provide the standard approach to diagnosis, treatment and follow-up of bone sarcoma patients in the Latin-American context

Multicomponent Exercise on Physical Function, Cognition and Hemodynamic Parameters of Community-Dwelling Older Adults: A Quasi-Experimental Study

This paper reports on a quasi-experimental study that aimed to identify changes in muscle function (i.e., mobility, maximal walking speed, lower limb muscle strength, balance, and transfer capacity), cognition (i.e., executive function) and hemodynamic parameters of community-dwelling Brazilian older adults during a six-month multicomponent exercise program (MCEP). A total of 436 community-dwelling older adults performed functional, cognitive and hemodynamic assessments before and after a six-month MCEP. The program of exercise was performed twice a week over 26 weeks at moderate intensity. Results indicate that balance, mobility (i.e., usual and maximal walking speeds) and transfer capacity (p &lt; 0.05) were significantly improved after the MCEP. Moreover, all hemodynamic parameters (i.e., systolic, diastolic and mean arterial pressures), except for heart rate (p &gt; 0.05), were significantly reduced after the intervention. The current findings indicate that a six-month MCEP may provide physical and hemodynamic benefits in community-dwelling older adults. Nevertheless, our findings need to be confirmed in larger samples and better designed studies

Implantes curtos em região posterior da mandíbula

The rehabilitation of edentulous areas with osseointegrated dental implants is a well-documented, predictable procedure in the literature, with high success rates. However, the lack of bone at the recipient bed or proximity to anatomic structures limits the rehabilitation procedure especially at the posterior mandible. Thus, short implants are an alternative treatment for such cases of severe bone resorption. The purpose of this study was to review the success rate of short implants, especially those based in the posterior mandible and to show a clinical case. A literature review was made on electronic databases PubMed and Bireme with articles published between the years 2005 to 2012, using the keywords "short dental implants". It was concluded that the success rates of short implants are similar to those presented by conventional implants but still related to their geometry and surface treatment. Also, short implants can be considered as a viable alternative for the rehabilitation of severely resorbed jaws. However, many authors consider that more research is necessary when a short implant is compared to a long dental implant.A reabilitação de regiões edêntulas com implantes dentários osseointegráveis é um procedimento previsível, bem documentado na literatura e com elevadas taxas de sucesso. Entretanto, a escassez óssea do leito receptor ou a proximidade com estruturas anatômicas limita o procedimento reabilitador, principalmente nas regiões posteriores da mandíbula. Dessa forma, os implantes curtos são uma alternativa de tratamento para esses casos de reabsorção óssea severa. O objetivo deste artigo foi fazer uma revisão da literatura para analisar a taxa de sucesso dos implantes curtos, destacando-se os instalados na região posterior da mandíbula, assim como apresentar um caso clínico. Para isso foi realizado um levantamento bibliográfico dos artigos publicados nos anos de 2005 a 2012, indexados na base de dados Pubmed e Bireme. Foi empregada a palavra-chave: implantes curtos. Concluiu-se que as taxas de sucesso dos implantes curtos são semelhantes às taxas de sucesso dos implantes convencionais e que essa taxa de sucesso está relacionada com a geometria e o tratamento das superfícies dos implantes curtos. Ainda, o implante curto pode ser considerado como uma alternativa viável para a reabilitação dos maxilares severamente reabsorvidos. Entretanto, muitos autores consideram que mais pesquisas são necessárias para se equivaler um implante curto com um implante longo