296 research outputs found
Voneinander Lernen: Ein Handbuch für Sprachlehrerverbände
The publication is aimed at those involved in the running of language teacher associations at international, national, regional and local levels. This may include paid employees or, more frequently, volunteers. It provides guidance on the effective running and networking of associations. It encourages language teacher associations to collaborate in order to support teachers more effectively, and to contribute to improvements in the quality of language teaching. It enables language teachers across the world to share their own ideas, to be involved in research, and to learn about the cutting-edge work of the ECML and its European projects
Apprendre les uns des autres: Manuel pour les associations de professeurs de langues
The publication is aimed at those involved in the running of language teacher associations at international, national, regional and local levels. This may include paid employees or, more frequently, volunteers. It provides guidance on the effective running and networking of associations. It encourages language teacher associations to collaborate in order to support teachers more effectively, and to contribute to improvements in the quality of language teaching. It enables language teachers across the world to share their own ideas, to be involved in research, and to learn about the cutting-edge work of the ECML and its European project
State and Transition Models in Space and Time – Using STMs to Understand Broad Patterns of Ecosystem Change in Iceland
Managing ecological systems sustainably requires a deep understanding of ecosystem structure and the processes driving their dynamics. Conceptual models can lead to improved management, by providing a framework for organizing knowledge about a system and identifying the causal agents of change. We developed state-and-transition models (STMs) to describe landscape changes in Iceland over three historical periods with different human influence, from pre-settlement to present days. Our models identified the set of possible states, transitions and thresholds in these ecosystems and their changes over time. To illustrate the use of these models for predicting and improving management interventions, we applied our present-day STM to a case study in the central highlands of Iceland and monitored ecosystem changes within an ongoing field experiment with two management interventions (grazing exclusion and fertilization) in areas experiencing contrasting stages of degradation. The results of the experiment broadly align with the predictions of the model and underscore the importance of conceptual frameworks for adaptive management, where the best available knowledge is used to continuously refine and update the models
Post-eruptive volcano inflation following major magma drainage: Interplay between models of viscoelastic response influence and models of magma inflow at Bárðarbunga caldera, Iceland, 2015-2018
<p>Unrest at Bárðarbunga after a caldera collapse in 2014-2015 includes elevated seismicity beginning about six months after the eruption ended, including nine Mw>4.5 earthquakes. The earthquakes occurred mostly on the northern and southern parts of a caldera ring fault. Global Navigation Satellite System (GNSS, in particular, Global Positioning System; GPS) and Interferometric Synthetic Aperture Radar (InSAR) geodesy are applied to evaluate the spatial and temporal pattern of ground deformation around Bárðarbunga caldera outside the icecap, in 2015-2018, when deformation rates were relatively steady. The aim is to study the role of viscoelastic relaxation following major magma drainage versus renewed magma inflow as an explanation for the ongoing unrest.</p><p>The largest horizontal velocity is measured at GPS station KISA (3 km from caldera rim), 141 mm/yr in direction N47<sup>o</sup>E relative to the Eurasian plate in 2015-2018. GPS and InSAR observations show that the velocities decay rapidly outward from the caldera. We correct our observations for Glacial Isostatic Adjustment and plate spreading to extract the deformation related to volcanic activity. After this correction, some GPS sites show subsidence.</p><p>We use a reference Earth model to initially evaluate the contribution of viscoelastic processes to the observed deformation field. We model the deformation within a half-space composed of a 7-km thick elastic layer on top of a viscoelastic layer with a viscosity of 5 x 10<sup>18</sup> Pa s, considering two co-eruptive contributors to the viscoelastic relaxation: “non-piston” magma withdrawal at 10 km depth (modelled as pressure drop in a spherical source) and caldera collapse (modelled as surface unloading). The other model we test is the magma inflow in an elastic half-space. Both the viscoelastic relaxation and magma inflow create horizontal outward movements around the caldera, and uplift at the surface projection of the source center in 2015-2018. Viscoelastic response due to magma withdrawal results in subsidence in the area outside the icecap. Magma inflow creates rapid surface velocity decay as observed.</p><p>We explore further two parameters in the viscoelastic reference model: the viscosity and the "non-piston" magma withdrawal volume. Our comparison between the corrected InSAR velocities and viscoelastic models suggests a viscosity of 2.6×10<sup>18</sup> Pa s and 0.36 km<sup>3</sup> of “non-piston” magma withdrawal volume, given by the optimal reduced Chi-squared statistic. When the deformation is explained using only magma inflow into a single spherical source (and no viscoelastic response), the optimal model suggests an inflow rate at 1×10<sup>7</sup> m<sup>3</sup>/yr at 700 m depth. A magma inflow model with more model parameters is also a possible explanation, including sill inflation at 10 km together with slip on caldera ring faults. Our reference Earth model and the two end-member models suggest that there is a trade-off between the viscoelastic relaxation and the magma inflow, since they produce similar deformation signals outside the icecap. However, to reproduce details of the observed deformation, both processes are required. A viscoelastic-only model cannot fully explain the fast velocity decay away from the caldera, whereas a magma inflow-only model cannot explain the subsidence observed at several locations.</p>
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Diagnostic accuracy of 64-slice computed tomography compared with coronary angiography
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/OpenObjective: The aim of this study was to evaluate the diagnostic accuracy (sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV)) of 64-slice multidetector computed tomography (MDCT) compared with quantitative coronary angiography (QCA) for detection of coronary artery disease (CAD). Material and methods: Sixty-nine patients participating in a study of coronary in-stent restenosis were investigated. After a 64-slice MDCT scan patients were evaluated by QCA. The coronary arteries were divided into 15 segments and stenosis was graded for each segment by both methods. The diagnostic accuracy of 64-slice MDCT was evaluated using the QCA as the gold standard. Results: Among the 69 patients included in the study 13 (19%) were female and 56 male. The mean age was 63 (SD 10) years. The following risk factors were present: high blood pressure 67%, elevated blood cholesterol 54%, diabetes 12% and family history of CAD 71%. Current smokers were 22% and previous smokers were 48%. Altogether 663 segments were examined. Of those 221 (33%) segments were excluded; 103 because of stents, 48 because of heavy calcification, 41 because of motion artifacts and 29 because the segments were less than 1.5 mm in diameter. The mean time between MDCT and QCA was 6.3 (SD 12.1) days. The sensitivity of 64-slice MDCT for diagnosing significant stenosis (>/= 50% according to QCA) was 20%, the specificity was 94%, PPV was 16%, NPV was 95% and the accuracy was 89%. Conclusion: High NPV and specificity indicates that MDCT is useful for accurately excluding significant CAD but the low sensitivity and low PPV indicate that the method is not accurate in diagnosing coronary artery stenosis of 50% or more according to QCA. Key words: coronary artery disease, multidetector computed tomography, cardiac catheterisation. Correspondence: Karl Andersen, [email protected]: Markmið rannsóknarinnar var að meta greiningarhæfni (næmi, sértæki, jákvætt forspárgildi, neikvætt forspárgildi og nákvæmni) 64 sneiða tölvusneiðmyndatækni (TS-tækni) á kransæðasjúkdómi með hjartaþræðingu sem viðmið. Efniviður og aðferðir: Rannsóknarhópurinn samanstóð af 69 sjúklingum sem tóku þátt í rannsókn á endurþrengslum í stoðnetum kransæða. Framkvæmd var TS af kransæðum til að meta æðaþrengsli. Nokkrum dögum síðar voru þátttakendur hjartaþræddir. Kransæðatrénu var skipt upp í 15 hluta. Æðaþrengsli voru metin í öllum hlutum æðatrésins með báðum aðferðunum. Greiningarhæfni 64 sneiða TS-tækni var metin og kransæðaþræðing höfð sem viðmið. Niðurstöður: Í rannsókninni voru 13 (19%) konur og 56 karlar. Meðalaldur þátttakenda var 63 (SD 10) ár, háþrýsting höfðu 67%, háar blóðfitur 54%, sykursýki 12% og ættarsaga um kransæðasjúkdóm var til staðar í 71% tilvika. Reykingamenn voru 22% og fyrrum reykingamenn 48%. Samtals 663 æðahlutar voru rannsakaðir. Af þeim voru 221 (33,4%) útilokaðir; 103 vegna stoðneta, 48 vegna truflana af völdum kalks, 41 vegna hreyfitruflana og 29 þar sem æðin var minni en 1,5 mm í þvermál. Meðaltími milli TS og hjartaþræðingar voru 6,3 (SD 12,1) dagar. Næmi 64 sneiða TS til greiningar marktækra þrengsla (?50% þrengsli samkvæmt hjartaþræðingu) var 20%, sértæki 94%, jákvætt forspárgildi 16%, neikvætt forspárgildi 95% og nákvæmni 89%. Ályktun: Hátt neikvætt forspárgildi og hátt sértæki gefur til kynna að TS-rannsókn sé gagnleg til að útiloka kransæðasjúkdóm. Lágt næmi og lágt jákvætt forspárgildi benda til að aðferðin sé ekki góð til að meta hvort kransæðaþrengsli séu 50% eða meiri við hjartaþræðingu
Education as Risk Factor of Mild Cognitive Impairment:The Link to the Gut Microbiome
Background: With differences apparent in the gut microbiome in mild cognitive impairment (MCI) and dementia, and risk factors of dementia linked to alterations of the gut microbiome, the question remains if gut microbiome characteristics may mediate associations of education with MCI. Objectives: We sought to examine potential mediation of the association of education and MCI by gut microbiome diversity or composition. Design: Cross-sectional study. Setting: Luxembourg, the Greater Region (surrounding areas in Belgium, France, Germany). Participants: Control participants of the Luxembourg Parkinson’s Study. Measurements: Gut microbiome composition, ascertained with 16S rRNA gene amplicon sequencing. Differential abundance, assessed across education groups (0–10, 11–16, 16+ years of education). Alpha diversity (Chao1, Shannon and inverse Simpson indices). Mediation analysis with effect decomposition was conducted with education as exposure, MCI as outcome and gut microbiome metrics as mediators. Results: After exclusion of participants below 50, or with missing data, n=258 participants (n=58 MCI) were included (M [SD] Age=64.6 [8.3] years). Higher education (16+ years) was associated with MCI (Odds ratio natural direct effect=0.35 [95% CI 0.15–0.81]. Streptococcus and Lachnospiraceae-UCG-001 genera were more abundant in higher education. Conclusions: Education is associated with gut microbiome composition and MCI risk without clear evidence for mediation. However, our results suggest signatures of the gut microbiome that have been identified previously in AD and MCI to be reflected in lower education and suggest education as important covariate in microbiome studies
Development of a Quality Index Method (QIM) for Maatjes Herring Stored in Air and Under Modified Atmosphere
Responses to projected changes in climate and UV-B at the species level
Environmental manipulation experiments showed that species respond individualistically to each environmental-change variable. The greatest responses of plants were generally to nutrient, particularly nitrogen, addition. Summer warming experiments showed that woody plant responses were dominant and that mosses and lichens became less abundant. Responses to warming were controlled by moisture availability and snow cover. Many invertebrates increased population growth in response to summer warming, as long as desiccation was not induced. CO2 and UV-B enrichment experiments showed that plant and animal responses were small. However, some microorganisms and species of fungi were sensitive to increased UV-B and some intensive mutagenic actions could, perhaps, lead to unexpected epidemic outbreaks. Tundra soil heating, CO 2 enrichment and amendment with mineral nutrients generally accelerated microbial activity. Algae are likely to dominate cyanobacteria in milder climates. Expected increases in winter freeze-thaw cycles leading to ice-crust formation are likely to severely reduce winter survival rate and disrupt the population dynamics of many terrestrial animals. A deeper snow cover is likely to restrict access to winter pastures by reindeer/caribou and their ability to flee from predators while any earlier onset of the snow-free period is likely to stimulate increased plant growth. Initial species responses to climate change might occur at the sub-species level: an Arctic plant or animal species with high genetic/racial diversity has proved an ability to adapt to different environmental conditions in the past and is likely to do so also in the future. Indigenous knowledge, air photographs, satellite images and monitoring show that changes in the distributions of some species are already occurring: Arctic vegetation is becoming more shrubby and more productive, there have been recent changes in the ranges of caribou, and "new" species of insects and birds previously associated with areas south of the treeline have been recorded. In contrast, almost all Arctic breeding bird species are declining and models predict further quite dramatic reductions of the populations of tundra birds due to warming. Species-climate response surface models predict potential future ranges of current Arctic species that are often markedly reduced and displaced northwards in response to warming. In contrast, invertebrates and microorganisms are very likely to quickly expand their ranges northwards into the Arctic
Experiment, monitoring, and gradient methods used to infer climate change effects on plant communities yield consistent patterns
Inference about future climate change impacts typically relies on one of three approaches: manipulative experiments, historical comparisons (broadly defined to include monitoring the response to ambient climate fluctuations using repeat sampling of plots, dendroecology, and paleoecology techniques), and space-for-time substitutions derived from sampling along environmental gradients. Potential limitations of all three approaches are recognized. Here we address the congruence among these three main approaches by comparing the degree to which tundra plant community composition changes (i) in response to in situ experimental warming, (ii) with interannual variability in summer temperature within sites, and (iii) over spatial gradients in summer temperature. We analyzed changes in plant community composition from repeat sampling (85 plant communities in 28 regions) and experimental warming studies (28 experiments in 14 regions) throughout arctic and alpine North America and Europe. Increases in the relative abundance of species with a warmer thermal niche were observed in response to warmer summer temperatures using all three methods; however, effect sizes were greater over broad-scale spatial gradients relative to either temporal variability in summer temperature within a site or summer temperature increases induced by experimental warming. The effect sizes for change over time within a site and with experimental warming were nearly identical. These results support the view that inferences based on space-for-time substitution overestimate the magnitude of responses to contemporary climate warming, because spatial gradients reflect long-term processes. In contrast, in situ experimental warming and monitoring approaches yield consistent estimates of the magnitude of response of plant communities to climate warming
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