Psychosocial factors at work and inflammatory markers: protocol for a systematic review and meta-analysis

Introduction Chronic inflammation may be a mediator for the development of cardiovascular disease (CVD), metabolic diseases and psychotic and neurodegenerative disorders. Meta-analytic associations between work-related psychosocial factors and inflammatory markers have shown that work-related psychosocial factors could affect the flexibility and balance of the immune system. However, few systematic reviews or meta-analyses have investigated the association between work-related psychosocial factors and inflammatory markers. Based on prospective studies, the present investigation will conduct a comprehensive systematic review and meta-analysis of the association between work-related psychosocial factors and inflammatory markers.Methods and analysis The systematic review and meta-analysis will include published studies identified from electronic databases (PubMed, EMBASE, PsycINFO, PsycARTICLES, Web of Science and Japan Medical Abstracts Society) according to recommendations of the Meta-analysis of Observational Studies in Epidemiology guideline. Inclusion criteria are studies that: examined associations between work-related psychosocial factors and increased inflammatory markers; used longitudinal or prospective cohort designs; were conducted among workers; provided sufficient data for calculating ORs or relative risk with 95% CIs; were published as original articles in English or Japanese; and were published up to the end of 2017. Study selection, data extraction, quality assessment and statistical syntheses will be conducted by 14 investigators. Any inconsistencies or disagreements will be resolved through discussion. The quality of studies will be evaluated using the Risk of Bias Assessment Tool for Non-randomized Studies.Ethics and dissemination The investigation study will be based on published studies, so ethics approval is not required. The results of this study will be submitted for publication in a scientific peer-reviewed journal. The findings may be useful for assessing risk factors for increased inflammatory markers in the workplace and determining future approaches for preventing CVD, metabolic diseases and psychotic and neurodegenerative disorders

Evaluation of a Triage Checklist for Mild COVID-19 Outpatients in Predicting Subsequent Emergency Department Visits and Hospitalization during the Isolation Period: A Single-Center Retrospective Study

Managing mild illness in COVID-19 and predicting progression to severe disease are concerning issues. Here, we investigated the outcomes of Japanese patients with mild COVID-19, and identified triage risk factors for further hospitalization and emergency department (ED) visits at a single tertiary hospital. A triage checklist with 30 factors was used. Patients recommended for isolation were followed up for 10 days for subsequent ED visits or hospital admission. Overall, 338 patients (median age, 44.0; 45% women) visited the clinic 5.0 days (median) after symptom onset. Thirty-six patients were immediately hospitalized following triage; others were isolated. In total, 72 non-hospitalized patients visited the ED during their isolation, and 30 were hospitalized after evaluation for oxygen desaturation. The median ED visit and hospitalization durations after symptom onset were 5.0 and 8.0 days, respectively. The checklist factors associated with hospitalization during isolation were age > 50 years, body mass index > 25 kg/m2, hypertension, tachycardia with pulse rate > 100/min or blood pressure > 135 mmHg at triage, and >3-day delay in hospital visit after symptom onset. No patients died. Altogether, 80% of patients with mild COVID-19 could be safely isolated at home. Age, BMI, underlying hypertension, date after symptom onset, tachycardia, and systolic blood pressure at triage might be related to later hospitalization

The impact of being bullied at school on psychological distress and work engagement in a community sample of adult workers in Japan

The aim of this study was to investigate the long-term impact of being bullied at school on current psychological distress and work engagement in adulthood among Japanese workers. We hypothesized that workers who had been bullied at school could have higher psychological distress and lower work engagement compared to those who had not been bullied.We used data from the Japanese Study on Stratification, Health, Income, and Neighborhood (J-SHINE) project, conducted from July 2010 to February 2011 in Japan. This survey randomly selected the local residents around a metropolitan area in Japan. Of 13,920 adults originally selected, 4,317 people participated this survey, and the total response rate was 31%. The self-administered questionnaires assessed current psychological distress (K6), work engagement (UWES), the experiences of being bullied in elementary or junior high school and other covariates. Statistical analyses were conducted only for workers. Hierarchical multiple regression analyses were conducted to determine associations between experiences of being bullied at school and psychological distress/work engagement, with six steps.Statistical analysis was conducted for 3,111 workers. The number of respondents who reported being bullied in elementary or junior high school was 1,318 (42%). We found that the experience of being bullied at school was significantly associated with high psychological distress in adulthood (β = .079, p = < .0001); however, the work engagement scores of respondents who were bullied were significantly higher than for people who were not bullied at school (β = .068, p = < .0001), after adjusting all covariates.Being bullied at school was positively associated with both psychological distress and work engagement in a sample of workers. Being bullied at school may be a predisposing factor for psychological distress, as previously reported. The higher levels of work engagement among people who experienced being bullied at school may be because some of them might have overcome the experience to gain more psychological resilience

Association between school bullying experience and work-related subjective well-being: A systematic review

Objectives: Work-related subjective well-being (SWB) may be negatively affected by early-life adverse experiences, such as school bullying experience. This study aimed to identify the association between work-related SWB and school bullying experiences. Methods: A systematic review was conducted using five electronic databases to search for published observational studies from inception to May 5th, 2022. Eligibility criteria included the original papers in English, which measured school bullying experiences and work-related SWB (eg, satisfaction, engagement). Eight researchers independently conducted screening and a full-text review. We used the Risk of Bias Assessment tool for Non-randomized Studies to assess the certainty of the evidence. Narrative data were summarized. The study has been registered at UMIN-CTR (UMIN000040513). Results: A total of 6,842 studies were initially searched. We included two cross-sectional studies. Both studies were rated as high risk for bias in exposure measurements and incomplete outcome data. These studies showed conflicting results. One study reported that school bullying was negatively associated with job satisfaction among British lesbian, gay, or bisexual workers; on the other hand, another study reported that school bullying was positively associated with work engagement among Japanese workers. Conclusions: We found limited inconsistent evidence for the association between work-related SWB and school bullying experiences

What is necessary to fight against tobacco vaporizers in Japan?

Introduction In Japan, recently not only smoking rates but also the consumptions of cigarettes are decreasing. Raising problem about tobacco is increasing users of tobacco vaporizers. To clarify points of problems, present situation of tobacco vaporizers was investigated. Subjects and Methods Data of tobacco vaporizers are collected from internet, newspapers and so forth. Results Tobacco vaporizers are a kind of e-cigarettes. Three vaporizers are available in Japan. They are IQOS, ploom TECh and glo. Most popular vaporizer is IQOS in Japan. One of the reasons that cigarette smokers change to IQOS is that it is allowed to use in some non-smoking places and restaurants. And it is advertised that negative health effect for the circumstance is smaller than that of cigarette smoking. As there are small evidences about negative health effects, regulations are depend on the local governments. The Ministry of Health, Labour and Welfare has not yet presented any policy for the vaporizers because of almost no evidence for their negative health effects. Discussion IQOS began to be sold since 2016 all over Japan. 80 % of its users all over the world is Japanese. The number of its user are rapidly increasing in Japan. Some of the users believe that using vaporizers is not smoking. But the vapor of it contains tars and other harmful materials like cigarettes. To diffuse facts of the vaporizers is necessary and regulations should be made by the precautional principles. Conclusion To disseminate the knowledge about the vaporizers is necessary in Japan

Associations between experience of being bullied and psychological distress (n = 3111).

<p>Associations between experience of being bullied and psychological distress (n = 3111).</p

Box plot comparing work engagement and being bullied at school.

<p>Box plot comparing work engagement and being bullied at school.</p

Participants’ flow chart.

<p>Participants’ flow chart.</p

Correlations between exposure variable, main outcomes and covariates (n = 3111).

<p>Correlations between exposure variable, main outcomes and covariates (n = 3111).</p

Box plot comparing psychological distress and being bullied at school.

<p>Box plot comparing psychological distress and being bullied at school.</p