4,962 research outputs found
Dressing Symmetries of Holomorphic BF Theories
We consider holomorphic BF theories, their solutions and symmetries. The
equivalence of Cech and Dolbeault descriptions of holomorphic bundles is used
to develop a method for calculating hidden (nonlocal) symmetries of holomorphic
BF theories. A special cohomological symmetry group and its action on the
solution space are described.Comment: 14 pages, LaTeX2
Elevated Plasma Levels of Vascular Endothelial Growth Factor and Hepatocyte Growth Factor: Clinical Significance and Correlation with Tumor Burden in Patients with Chronic Myeloid Leukemia
Angiogenesis is an established indispensable process in the development and metastasis of solid tumors. Its significance in the pathogenesis and progression of hematological malignancies is still to be elucidated. Data have recently been accumulated about its role in chornic myeloid leukemia (CML). The aims of our study were: (I) to assess vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) plasma levels in patients with newly diagnosed, untreated and treated CML; (II) to analyze the differences of their levels in varying phases of the disease; (III) to analyze VEGF and HGF correlation with some markers reflecting the tumor burden as well as the progression of the disease. Plasma levels of VEGF and HGF were determined by ELISA in 16 patients with CML and 21 healthy individuals. VEGF and HGF levels were followed-up in 6 patients according to the progression of the disease or the treatment regimen. All the patients with CML showed significantly higher levels of VEGF and HGF when compared to the control group. We found a significant correlation between HGF and leukocytes, LDH, splenomegaly and blast percentage in the peripheral blood. Significant correlation was found between VEGF and platelets, LDH and leukocytes. Our data indicate that CML are highly associated with elevated plasma levels of VEGF and HGF, wich corroborates the thesis of its angiogenic dependency. Likewise, the present study suggests that measurements of VEGF and HGF may be useful for assessing disease activity and progression as well
Prospects for the implementation of the "digital government" project of the Russian Federation
The theoretical foundations for the development of the digital economy and e-government are considered in this article. The main objectives of Russia's transition to the digital economy are listed. The relevance of the development of the digital government concept is considered.
The indicators of the current level of state development in the framework of digitalization and the formation of e-government are analyzed. The main problems, the solution of which makes the implementation of the digital government project of the Russian Federation possible, are singled out.
Digital economy development is associated not only with the progress of the information technology and innovation industry, but also with the improvement of the labor market, where new jobs, professions and personnel are created.
In this regard, there is a rapid process of the foundation of society, where one job becomes low-paid, and new professions allow one to receive a personal income at the level of top managers of small and medium-sized enterprises.peer-reviewe
On the estimate of the sigma^(I = 1)_(KN)(0)-term value from the energy level shift of kaonic hydrogen in the ground state
Using the experimental data on the energy level shift of kaonic hydrogen in
the ground state (the DEAR Collaboration, Phys. Rev. Lett. 94, 212302 (2005))
and the theoretical value of the energy level shift, calculated within the
phenomenological quantum field theoretic approach to the description of strong
low-energy anti-K N and anti-K NN interactions developed at Stefan Meyer
Institut fuer subatomare Physik in Vienna, we estimate the value of the
sigma^(I = 1)_(KN)(0)-term of low-energy anti-K N scattering. We get sigma^(I =
1)_(KN)(0) = (433 +/- 85) MeV. This testifies the absence of strange quarks in
the proton structure.Comment: 7 pages, no figure
Supernova Ia: a Converging Delayed Detonation Wave
A model of a carbon-oxygen (C--O) presupernova core with an initial mass 1.33
M_\odot, an initial carbon mass fraction 0.27, and with an average mass
growth-rate 5 x 10^{-7} M_\odot/yr due to accretion in a binary system was
evolved from initial central density 10^9 g/cm^3, and temperature 2.05 x 10^8 K
through convective core formation and its subsequent expansion to the carbon
runaway at the center. The only thermonuclear reaction contained in the
equations of evolution and runaway was the carbon burning reaction 12C + 12C
with an energy release corresponding to the full transition of carbon and
oxygen (with the same rate as carbon) into 56Ni. As a parameter we take
\alpha_c - a ratio of a mixing length to the size of the convective zone. In
spite of the crude assumptions, we obtained a pattern of the runaway acceptable
for the supernova theory with the strong dependence of its duration on
\alpha_c. In the variants with large enough values of \alpha_c=4.0 x 10^{-3}
and 3.0 x 10^{-3} the fuel combustion occurred from the very beginning as a
prompt detonation. In the range of 2.0 x 10^{-3} >= \alpha_c >= 3.0 x 10^{-4}
the burning started as a deflagration with excitation of stellar pulsations
with growing amplitude. Eventually, the detonation set in, which was activated
near the surface layers of the presupernova (with m about 1.33 M_\odot) and
penetrated into the star down to the deflagration front. Excitation of model
pulsations and formation of a detonation front are described in detail for the
variant with \alpha_c=1.0 x 10^{-3}.Comment: 13 pages, 11 figures, to appear in Astronomy Letter
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