Виртуальная лаборатория на базе стенда AVR-микролаб

В статті розглянуті шляхи створення сучасної учбової лабораторії враховуючи матеріальні труднощі сучасної освіти.This paper is devoted to consider ways of making a modern student’s laboratory, taking into account financial troubles in the modern education

Определение содержания нефтепродуктов и продуктов сгорания угля в воде и донных отложениях реки Томь

Почвенный покров и водоемы - основные ресурсы жизнедеятельности человека - в первую очередь страдают от химических загрязнений, поэтому их состояние очень важно для характеристики природной среды.Soil and water - the basic resources of human life - the first to suffer from chemical pollution, so their status is very important for the characteristics of the natural environment

Creativity in Engineering Education

The paper examines the creativity in engineering education. The authors substantiate the topicality of the training of creative professionals in Russia and abroad and present training of creative professionals experience at the Department of Engineering Entrepreneurship of NR TPU. The empirical basis of the paper is the definition of the algorithm and conditions of the training of creative professionals

TET1 is a tumor suppressor of hematopoietic malignancy

The methylcytosine dioxygenase TET1 (‘ten-eleven translocation 1’) is an important regulator of 5-hydroxymethylcytosine (5hmC) in embryonic stem cells. The diminished expression of TET proteins and loss of 5hmC in many tumors suggests a critical role for the maintenance of this epigenetic modification. Here we found that deletion of Tet1 promoted the development of B cell lymphoma in mice. TET1 was required for maintenance of the normal abundance and distribution of 5hmC, which prevented hypermethylation of DNA, and for regulation of the B cell lineage and of genes encoding molecules involved in chromosome maintenance and DNA repair. Whole-exome sequencing of TET1-deficient tumors revealed mutations frequently found in non-Hodgkin B cell lymphoma (B-NHL), in which TET1 was hypermethylated and transcriptionally silenced. Our findings provide in vivo evidence of a function for TET1 as a tumor suppressor of hematopoietic malignancy.National Institutes of Health (U.S.) (5RO1HD045022)National Institutes of Health (U.S.) (5R37CA084198

Mechanistic Studies of Ethylene Hydrophenylation Catalyzed by Bipyridyl Pt(II) Complexes

This article discusses mechanistic studies of ethylene hydrophenylation catalyzed by bipyridyl Pt(II) complexes