52 research outputs found
Vector Continued Fractions using a Generalised Inverse
A real vector space combined with an inverse for vectors is sufficient to
define a vector continued fraction whose parameters consist of vector shifts
and changes of scale. The choice of sign for different components of the vector
inverse permits construction of vector analogues of the Jacobi continued
fraction. These vector Jacobi fractions are related to vector and scalar-valued
polynomial functions of the vectors, which satisfy recurrence relations similar
to those of orthogonal polynomials. The vector Jacobi fraction has strong
convergence properties which are demonstrated analytically, and illustrated
numerically.Comment: Published form - minor change
Symptomatic hypogammaglobulinemia in infancy and childhood – clinical outcome and in vitro immune responses
BACKGROUND: Symptomatic hypogammaglobulinemia in infancy and childhood (SHIC), may be an early manifestation of a primary immunodeficiency or a maturational delay in the normal production of immunoglobulins (Ig). We aimed to evaluate the natural course of SHIC and correlate in vitro lymphoproliferative and secretory responses with recovery of immunoglobulin values and clinical resolution. METHODS: Children, older than 1 year of age, referred to our specialist clinic because of recurrent infections and serum immunoglobulin (Ig) levels 2 SD below the mean for age, were followed for a period of 8 years. Patient with any known familial, clinical or laboratory evidence of cellular immunodeficiency or other immunodeficiency syndromes were excluded from this cohort. Evaluation at 6- to 12-months intervals continued up to 1 year after resolution of symptoms. In a subgroup of patients, in vitro lymphocyte proliferation and Ig secretion in response to mitogens was performed. RESULTS: 32 children, 24 (75%) males, 8 (25%) females, mean age 3.4 years fulfilled the inclusion criteria. Clinical presentation: ENT infections 69%, respiratory 81%, diarrhea 12.5%. During follow-up, 17 (53%) normalized serum Ig levels and were diagnosed as transient hypogammaglobulinemia of infancy (THGI). THGI patients did not differ clinically or demographically from non-transient patients, both having a benign clinical outcome. In vitro Ig secretory responses, were lower in hypogammaglobulinemic, compared to normal children and did not normalize concomitantly with serum Ig's in THGI patients. CONCLUSIONS: The majority of children with SHIC in the first decade of life have THGI. Resolution of symptoms as well as normalization of Ig values may be delayed, but overall the clinical outcome is good and the clinical course benign
Relative prevalence of malformations at birth among different religious communities in Israel
Interrogating Boundaries and Acknowledging Fluidity: Shifting Identity Markers in Palestine/Israel
The struggle for equal rights for women in the early jewish defense underground: bar giora and ha’shomer, 1907-1918
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