Distribution of the alien freshwater fishes in the Ryukyu Archipelago

琉球大学21世紀COEプログラム主催　国際ワークショップ 「生物多様性と侵略的外来種 : 世界各地の事例からの教訓」, 日時：2008年11月1日, 会場：琉球大学法文学部講義棟大講義室, 発行元：琉球大学21世紀COEプログラ

Application of electroplated Ni–Fe thick film to magnetostrictive material in vibration power generator

Ni100−xFex (at. %) films of about 37 μm thickness are electroplated on Cu base plates of 50 mm length, 10 mm width, and 300 μm thickness by varying the composition from x = 0 to 99. They are applied to cantilevers in magnetostrictive vibration power generators. The influences of magnetic and magnetostrictive properties of electroplated film on the vibration power generation property are systematically investigated. The films with x = 41–65 show low coercivities of about 4 Oe reflecting the low magnetocrystalline anisotropy constants. Large negative magnetostriction is recognized for the films with x = 0–14, whereas large positive magnetostriction is observed for the films with x = 57–80. The cantilevers are vibrated at the respective resonance frequencies of about 105–115 Hz and with the acceleration of 1.5 G while applying the bias magnetic field in a range of 0–300 Oe along the length direction. The output voltages are detected by using a coil with 8000 turns. Peak voltages higher than 1 V are obtained for the films with x = 61–65 whose coercivities are low and magnetostrictions are large. The present study has shown that an Ni–Fe film not only with large magnetostriction but also with low magnetic anisotropy constant is useful as the magnetostrictive material in vibration power generator

Nonvortical Rashba Spin Structure on a Surface with C1h Symmetry

A totally anisotropic peculiar Rashba-Bychkov (RB) splitting of electronic bands was found on the Tl/Si(110)-(1×1) surface with C1h symmetry by angle- and spin-resolved photoelectron spectroscopy and first-principles theoretical calculation. The constant energy contour of the upper branch of the RB split band has a warped elliptical shape centered at a k point located between Γ and the edge of the surface Brillouin zone, i.e., at a point without time-reversal symmetry. The spin-polarization vector of this state is in-plane and points almost the same direction along the whole elliptic contour. This novel nonvortical RB spin structure is confirmed as a general phenomenon originating from the C1h symmetry of the surface

Nonvortical Rashba Spin Structure on a Surface with C1h Symmetry

A totally anisotropic peculiar Rashba-Bychkov (RB) splitting of electronic bands was found on the Tl=Sið110Þ-ð1 × 1Þ surface with C1h symmetry by angle- and spin-resolved photoelectron spectroscopy and first-principles theoretical calculation. The constant energy contour of the upper branch of the RB split band has a warped elliptical shape centered at a k point located between ¯Γ and the edge of the surface Brillouin zone, i.e., at a point without time-reversal symmetry. The spin-polarization vector of this state is in-plane and points almost the same direction along the whole elliptic contour. This novel nonvortical RB spin structure is confirmed as a general phenomenon originating from the C1h symmetry of the surface. © 2016 American Physical Society3

Long-term safety and efficacy of alogliptin, a DPP-4 inhibitor, in patients with type 2 diabetes: a 3-year prospective, controlled, observational study (J-BRAND Registry)

Introduction Given an increasing use of dipeptidyl peptidase-4 (DPP-4) inhibitors to treat patients with type 2 diabetes mellitus in the real-world setting, we conducted a prospective observational study (Japan-based Clinical Research Network for Diabetes Registry: J-BRAND Registry) to elucidate the safety and efficacy profile of long-term usage of alogliptin.Research design and methods We registered 5969 patients from April 2012 through September 2014, who started receiving alogliptin (group A) or other classes of oral hypoglycemic agents (OHAs; group B), and were followed for 3 years at 239 sites nationwide. Safety was the primary outcome. Symptomatic hypoglycemia, pancreatitis, skin disorders of non-extrinsic origin, severe infections, and cancer were collected as major adverse events (AEs). Efficacy assessment was the secondary outcome and included changes in hemoglobin A1c (HbA1c), fasting blood glucose, fasting insulin and urinary albumin.Results Of the registered, 5150 (group A: 3395 and group B: 1755) and 5096 (3358 and 1738) were included for safety and efficacy analysis, respectively. Group A patients mostly (>90%) continued to use alogliptin. In group B, biguanides were the primary agents, while DPP-4 inhibitors were added in up to ~36% of patients. The overall incidence of AEs was similar between the two groups (42.7% vs 42.2%). Kaplan-Meier analysis revealed the incidence of cancer was significantly higher in group A than in group B (7.4% vs 4.8%, p=0.040), while no significant incidence difference was observed in the individual cancer. Multivariate Cox regression analysis revealed that the imbalanced patient distribution (more elderly patients in group A than in group B), but not alogliptin usage per se, contributed to cancer development. The incidence of other major AE categories was with no between-group difference. Between-group difference was not detected, either, in the incidence of microvascular and macrovascular complications. HbA1c and fasting glucose decreased significantly at the 0.5-year visit and nearly plateaued thereafter in both groups.Conclusions Alogliptin as a representative of DPP-4 inhibitors was safe and durably efficacious when used alone or with other OHAs for patients with type 2 diabetes in the real world setting