Primary cutaneous B-cell lymphoma and chronic leg ulcers in a patient with type 2 diabetes

The incidences of type 2 diabetes mellitus and many cancers are rapidly increasing worldwide. Diabetes is a strong risk factor for some cancers (including lymphomas) and is also associated with adverse cancer outcomes. After gastrointestinal tract, the skin is the second most frequent extranodal site involved by non-Hodgkin lymphomas and the cutaneous B-cell lymphomas (CBCLs) range from 25% to 30% of all primary cutaneous lymphomas. The primary cutaneous diffuse large B-cell lymphoma (PCDLBCL) is an aggressive lymphoma with a poor prognosis, representing roughly 20% of all primary CBCLs. Classically, the cutaneous manifestation of this lymphoma is a red or violaceous tumors arising on a leg. To date, despite the large body of evidence suggesting that diabetes is strongly associated with an increased risk of some cancers, very little information is available regarding a possible association between type 2 diabetes and primary cutaneous diffuse large B-cell lymphoma. In this report, we will present the case of a white adult patient with type 2 diabetes with chronic leg ulcers complicated by a primary cutaneous diffuse large B-cell lymphoma

Improving the sustainability of tobacco cultivation by optimizing nitrogen fertilization

Tobacco covers over 4.3 million hectares of agricultural lands in the world and, as other crops, must be grown following sustainability principles. Tobacco Burley type is fertilized worldwide with rates of nitrogen that can be reduced without significant impact on product yield and quality. In this experiment, Burley tobacco (Nicotiana tabacum L.) plants were grown in the field with or without irrigation and fertilized with 0, 120, 240 or 360 kg N ha−1 over two growing seasons. The experimental design was a split-plot, with irrigation treatments in the main plots and doses of N in the sub-plots, with three replications. The elemental plot area was 100 m (10 x 10 m) in both years. The objective was to address N needs based on critical concentrations of N (Nct) and Nitrogen Nutrition Index (NNI), both of which are not available for this crop. Plant dry matter and leaf area were measured during the crop cycle. Specific leaf weight, total N, Nct and NNI were determined. Nct ranged between 2.2 and 4.0% in 2 years. NNI was greater under non-irrigated than irrigated conditions in both years and they generally increased significantly with N fertilization up to 240 kg N ha-1. NNI measured during the rapid growth was positively correlated with yield under irrigated conditions (r = 0.656*). Based on our results, when water is not limiting, the NNI measured at early growth stages could give a useful indication of the effectiveness of fertilization, i.e. the higher the NNI will be in this phase the better will be the response in terms of cured leaves production

O “ser homem” nos serviços oferecidos pela Estratégia Saúde da Família: olhar do usuário

This essay aims to evaluate the user's knowledge and suggestions about the provision of specific services towaers men's health in Primary Care, the subject of few published studies. 101 men were interviewed in the 14 Family Health Strategy teams in an urban area of a municipality located in the state of Minas Gerais. Thematic Analysis technique has been employed. Dissatisfaction extended awainting periods for assistance, scheduling appointments, lack of empathy for health professionals, criticismo about the absence of actions to promote health, divulgation campaigns, flaws in public administration and active search for men's health services were indentify; the gender issue reflected the social context of “being a man”, with the health service traditionally organized from a maternal and child perspective, which marginalizes the target audience and does not include the dimensions of masculinity.O trabalho buscou identificar o conhecimento do usuário e suas propostas acerca da oferta de serviços específicos à saúde do homem na Atenção Básica, tema de poucos estudos publicados. Foram entrevistados 101 homens nas 14 equipes da Estratégia Saúde da Família da zona urbana de um município do Estado de Minas Gerais. Utilizou-se a técnica de Análise Temática. Identificou-se insatisfação com o tempo de espera para o atendimento, marcação de consultas; falta de empatia dos profissionais de saúde; criticou-se a ausência de ações de promoção à saúde, divulgação de campanhas, falhas na administração pública e busca ativa para serviços em saúde do homem; a questão de gênero refletiu o contexto social do “ser homem”, sendo o serviço de saúde tradicionalmente organizado na perspectiva materno-infantil, o que marginaliza o público-alvo e não contempla as dimensões da masculinidade