68 research outputs found

    Bio-nanotechnology application in wastewater treatment

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    The nanoparticles have received high interest in the field of medicine and water purification, however, the nanomaterials produced by chemical and physical methods are considered hazardous, expensive, and leave behind harmful substances to the environment. This chapter aimed to focus on green-synthesized nanoparticles and their medical applications. Moreover, the chapter highlighted the applicability of the metallic nanoparticles (MNPs) in the inactivation of microbial cells due to their high surface and small particle size. Modifying nanomaterials produced by green-methods is safe, inexpensive, and easy. Therefore, the control and modification of nanoparticles and their properties were also discussed

    Role of Cancer Microenvironment in Metastasis: Focus on Colon Cancer

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    One person on three will receive a diagnostic of cancer during his life. About one third of them will die of the disease. In most cases, death will result from the formation of distal secondary sites called metastases. Several events that lead to cancer are under genetic control. In particular, cancer initiation is tightly associated with specific mutations that affect proto-oncogenes and tumour suppressor genes. These mutations lead to unrestrained growth of the primary neoplasm and a propensity to detach and to progress through the subsequent steps of metastatic dissemination. This process depends tightly on the surrounding microenvironment. In fact, several studies support the point that tumour development relies on a continuous cross-talk between cancer cells and their cellular and extracellular microenvironments. This signaling cross-talk is mediated by transmembrane receptors expressed on cancer cells and stromal cells. The aim of this manuscript is to review how the cancer microenvironment influences the journey of a metastatic cell taking liver invasion by colorectal cancer cells as a model

    Clinical practice guidelines for the management of hypothyroidism

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    Robust sparse network equivalent for large systems: Part I - Methodology

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    This paper deals with the calculation of a sparse network equivalent (SNE) for the analysis of electromagnetic transients in large systems. The main feature of the new approach is the enforcement of sparsity, stability, passivity, and accuracy at specific frequencies of the equivalent. The procedure is based on time-domain fitting with quadratic programming to enforce the constraints. The SNE can be interfaced with transient calculation programs directly in time domain. Results are presented in the companion paper.19115716

    Robust sparse network equivalent for large systems: Part II - Performance evaluation

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    This paper deals with the calculation of a sparse network equivalent (SNE) for the analysis of electromagnetic transients in large systems. The methodology and the mathematical details are presented in the companion paper [1]. This sequel presents application examples to demonstrate the accuracy and computational efficiency of the SNE. Equivalents for networks composed of 12, 50, and 100 transmission lines are derived and the results are discussed.19129329

    Nonlinear Control of Static Var Systems

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