3,933 research outputs found
Miscible displacement fronts of shear thinning fluids inside rough fractures
The miscible displacement of a shear-thinning fluid by another of same
rheological properties is studied experimentally in a transparent fracture by
an optical technique imaging relative concentration distributions. The fracture
walls have complementary self-affine geometries and are shifted laterally in
the direction perpendicular to the mean flow velocity {\bf U} : the flow field
is strongly channelized and macro dispersion controls the front structure for
P\'{e}clet numbers above a few units. The global front width increases then
linearly with time and reflects the velocity distribution between the different
channels. In contrast, at the local scale, front spreading is similar to Taylor
dispersion between plane parallel surfaces. Both dispersion mechanisms depend
strongly on the fluid rheology which shifts from Newtonian to shear-thinning
when the flow rate increases. In the latter domain, increasing the
concentration enhances the global front width but reduces both Taylor
dispersion (due to the flattening of the velocity profile in the gap of the
fracture) and the size of medium scale front structures
Multiparametric MRI and [18F]fluorodeoxyglucose positron emission tomography imaging is a potential prognostic imaging biomarker in recurrent glioblastoma
Purpose/objectivesMultiparametric advanced MR and [18F]fluorodeoxyglucose (FDG)-positron emission tomography (PET) imaging may be important biomarkers for prognosis as well for distinguishing recurrent glioblastoma multiforme (GBM) from treatment-related changes.Methods/materialsWe retrospectively evaluated 30 patients treated with chemoradiation for GBM and underwent advanced MR and FDG-PET for confirmation of tumor progression. Multiparametric MRI and FDG-PET imaging metrics were evaluated for their association with 6-month overall (OS) and progression-free survival (PFS) based on pathological, radiographic, and clinical criteria.Results17 males and 13 females were treated between 2001 and 2014, and later underwent FDG-PET at suspected recurrence. Baseline FDG-PET and MRI imaging was obtained at a median of 7.5 months [interquartile range (IQR) 3.7–12.4] following completion of chemoradiation. Median follow-up after FDG-PET imaging was 10 months (IQR 7.2–13.0). Receiver-operator characteristic curve analysis identified that lesions characterized by a ratio of the SUVmax to the normal contralateral brain (SUVmax/NB index) >1.5 and mean apparent diffusion coefficient (ADC) value of ≤1,400 × 10−6 mm2/s correlated with worse 6-month OS and PFS. We defined three patient groups that predicted the probability of tumor progression: SUVmax/NB index >1.5 and ADC ≤1,400 × 10−6 mm2/s defined high-risk patients (n = 7), SUVmax/NB index ≤1.5 and ADC >1,400 × 10−6 mm2/s defined low-risk patients (n = 11), and intermediate-risk (n = 12) defined the remainder of the patients. Median OS following the time of the FDG-PET scan for the low, intermediate, and high-risk groups were 23.5, 10.5, and 3.8 months (p < 0.01). Median PFS were 10.0, 4.4, and 1.9 months (p = 0.03). Rates of progression at 6-months in the low, intermediate, and high-risk groups were 36, 67, and 86% (p = 0.04).ConclusionRecurrent GBM in the molecular era is associated with highly variable outcomes. Multiparametric MR and FDG-PET biomarkers may provide a clinically relevant, non-invasive and cost-effective method of predicting prognosis and improving clinical decision making in the treatment of patients with suspected tumor recurrence
Superfluid and Pseudo-Goldstone Modes in Three Flavor Crystalline Color Superconductivity
We study the bosonic excitations in the favorite cubic three flavor
crystalline LOFF phases of QCD. We calculate in the Ginzburg-Landau
approximation the masses of the eight pseudo Nambu-Goldstone Bosons (NGB)
present in the low energy theory. We also compute the decay constants of the
massless NGB Goldstones associated to superfluidity as well as those of the
eight pseudo NGB. Differently from the corresponding situation in the
Color-Flavor-Locking phase, we find that meson condensation phases are not
expected in the present scenario.Comment: 10 pages, RevTeX4 class. Section IIIA enlarged, to appear on Phys.
Rev.
Influence of the disorder on tracer dispersion in a flow channel
Tracer dispersion is studied experimentally in periodic or disordered arrays
of beads in a capillary tube. Dispersion is measured from light absorption
variations near the outlet following a steplike injection of dye at the inlet.
Visualizations using dye and pure glycerol are also performed in similar
geometries. Taylor dispersion is dominant both in an empty tube and for a
periodic array of beads: the dispersivity increases with the P\'eclet
number respectively as and and is larger by a factor of 8
in the second case. In a disordered packing of smaller beads (1/3 of the tube
diameter) geometrical dispersion associated to the disorder of the flow field
is dominant with a constant value of reached at high P\'eclet numbers.
The minimum dispersivity is slightly higher than in homogeneous nonconsolidated
packings of small grains, likely due heterogeneities resulting from wall
effects. In a disordered packing with the same beads as in the periodic
configuration, is up to 20 times lower than in the latter and varies as
with or (depending on the fluid viscosity).
A simple model accounting for this latter result is suggested.Comment: available online at
http://www.edpsciences.org/journal/index.cfm?edpsname=epjap&niv1=contents&niv2=archive
Force-displacement distributions and percolation properties in simulated 2-D packings
The first part of this paper studies the behavior of contact force distributions and displacement distributions in isostatic 2-D arrays of polydispersed grains as a function of force strength and displacement strength, respectively. The array is built by pouring disks, one by one, into a rectangular die. After the array is ready, force and displacement measurements are performed on it. We also introduce a relaxation procedure (rearrangements of disks) in order to study the behavior of the corresponding distributions as a function of the number of relaxations performed on the system. In the second part, we characterize the percolation of small particles through this 2-D packings as a function of the polydispersivity of the disks. We analyze both trapping and non-trapping regimes. Characteristic features of these packings are discussed.Fil: Vidales, Ana Maria. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - San Luis. Instituto de FÃsica Aplicada "Dr. Jorge Andrés Zgrablich". Universidad Nacional de San Luis. Facultad de Ciencias FÃsico Matemáticas y Naturales. Instituto de FÃsica Aplicada "Dr. Jorge Andrés Zgrablich"; ArgentinaFil: Ippolito, I.. Universite de Rennes I; FranciaFil: Moukarzel, Cristian Fernando. Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional; Méxic
Circular solar: Evaluating the profitability of a photovoltaic panel recycling plant
Photovoltaic (PV) panels have a crucial role in coping with the global warming mitigation and the energetic crisis currently affecting the European Community. However, from the circular perspective of end-of-life (EoL) management, there are still big issues to be solved in order to recover materials from this kind of e-wastes. Because of several reasons (e.g. type of embedded materials, illegal shipments, location of manufacturers) EoL businesses do not have the interest in approaching them. This poses a significant environmental concern in terms of their management. This work wants to assess the profitability of a specific PV module recycling plant, by evaluating several market contexts in which multiple scenarios of material price, investment and process costs will be considered. The results for a 3000 tonnes plant show that profitability is not verified in the absence of an avoided landfill cost. Instead, when a value of 200 euro/tonnes is applied, the net present value is positive in 35.2% of the scenarios and at 87.6% when a value of 350 euro/tonnes is considered. The policy choice of this value requires linking the PV module disposal fee to the circular benefits associated with its recovery
Large Scale Control of Deferrable Domestic Loads in Smart Grids
In this paper, we investigate a realistic and low- cost deployment of large scale direct control of inelastic home appliances whose energy demand cannot be shaped, but simply deferred. The idea is to exploit 1) some simple actuators to be placed on the electric plugs for connecting or disconnecting appliances with heterogeneous control interfaces, including non- smart appliances, and 2) the Internet connections of customers for transporting the activation requests from the actuators to a centralized controller. Our solution requires no interaction with home users: in particular, it does not require them to express their energy demand in advance. A queuing theory model is derived to quantify how many users should adopt this solution in order to control a significant aggregated power load without significantly impairing their quality of service
A feasibility study for a circular approach in oil refining: Metals recovery from hydrodesulphurization catalysts
The paper deals with a profitability analysis developed for a plant that recycles spent hydrodesulphurization (HDS) catalysts. Such catalysts contain molybdenum (Mo), nickel (Ni), and vanadium (V), supported by an alumina (Al2O3) carrier. The recycling process is based on a double thermal pre-treatment stage, followed by a series of hydrometallurgical steps that allow recovering Mo and V and a Ni concentrate that need further refining for separation and recovery of the metals. The economic analysis is based on the discounted cash flow method, and the baseline case analyses show that the net present value (NPV) is 14,877 thousand EUR. The selling price of vanadium pentoxide strongly influences the results. Alternative scenarios are also studied to strengthen the results obtained, considering the sensitivity, scenario and risk analyses. Profitability is confirmed in 87% of the considered scenarios, and in about 81.5%, the NPV of the baseline scenario is achieved. Circular economy models can be realized if products are recovered and if there are technologies that can recover metals. This study confirms that an example of a circular economy is met from the proposed viability analysis, and the economic benefits can be significant
Strong extinction of a far-field laser beam by a single quantum dot
Through the utilization of index-matched GaAs immersion lens techniques we
demonstrate a record extinction (12%) of a far-field focused laser by a single
InAs/GaAs quantum dot. This contrast level enables us to report for the first
time resonant laser transmission spectroscopy on a single InAs/GaAs quantum dot
without the need for phase-sensitive lock-in detection
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