Scientific discovery reloaded

The way scientific discovery has been conceptualized has changed drastically in the last few decades: its relation to logic, inference, methods, and evolution has been deeply reloaded. The ‘philosophical matrix’ moulded by logical empiricism and analytical tradition has been challenged by the ‘friends of discovery’, who opened up the way to a rational investigation of discovery. This has produced not only new theories of discovery (like the deductive, cognitive, and evolutionary), but also new ways of practicing it in a rational and more systematic way. Ampliative rules, methods, heuristic procedures and even a logic of discovery have been investigated, extracted, reconstructed and refined. The outcome is a ‘scientific discovery revolution’: not only a new way of looking at discovery, but also a construction of tools that can guide us to discover something new. This is a very important contribution of philosophy of science to science, as it puts the former in a position not only to interpret what scientists do, but also to provide and improve tools that they can employ in their activity

Manufacturing a mathematical group: a study in heuristics

I examine the way a relevant conceptual novelty in mathematics, that is, the notion of group, has been constructed in order to show the kinds of heuristic reasoning that enabled its manufacturing. To this end, I examine salient aspects of the works of Lagrange, Cauchy, Galois and Cayley (Sect. 2). In more detail, I examine the seminal idea resulting from Lagrange’s heuristics and how Cauchy, Galois and Cayley develop it. This analysis shows us how new mathematical entities are generated, and also how what counts as a solution to a problem is shaped and changed. Finally, I argue that this case study shows us that we have to study inferential micro-structures (Sect. 3), that is, the ways similarities and regularities are sought, in order to understand how theoretical novelty is constructed and heuristic reasoning is put forwar

An Empirical Analysis on the European Market of Human Experimentation

The target of this work is to support the thesis that pharmaceutical companies' testing phase would be treated like any other form of production in a globalization process, that is to say, a specific phase of pharmaceutical R&D could be localized where the cost of clinical evidence is lower. Considering Europe, an empirical analysis in order to support the main hypothesis is performed. Taking trials of phases II and III, funded by Industry (dependent variable) and the main macroeconomic features (independent variables) of each nation into account, the empirical work is implemented via regression analysis on panel data (2000 - 2007). The sample analyzed considers EU-27 plus the candidate states (Croatia, the Former Yugoslav Republic of Macedonia, Turkey), Norway, Switzerland and Iceland. Results suggest the appropriateness of this process since clinical research is clearly affected by economic conditions, regardless of the scientific purpose.Pharmaceutical Company R&D; Human experimentation; Medical Researcher; Research Subject;

Imagining a New Italy to Create Italians. Le Vie d’Italia from 1917 to 1935

This article is situated in the framework of the editorial products through which Touring reinvented tourism and travel in the early part of the 1900s. It concentrates on the magazine Le Vie d’Italia, proposing a rereading starting from the covers, which, up through 1935, exhibited a product, or rather, an Italian product brand each month in place of the traditional beauty of the landscape. These covers/manifestos suggest a new visual of the landscape and build the new view for Italians, relying on the rhetorical mechanism—amply tested historically—of figures of the landscape operating as a topic

On the Energy Increase in Space-Collapse Models

A typical feature of spontaneous collapse models which aim at localizing wavefunctions in space is the violation of the principle of energy conservation. In the models proposed in the literature the stochastic field which is responsible for the localization mechanism causes the momentum to behave like a Brownian motion, whose larger and larger fluctuations show up as a steady increase of the energy of the system. In spite of the fact that, in all situations, such an increase is small and practically undetectable, it is an undesirable feature that the energy of physical systems is not conserved but increases constantly in time, diverging for $t \to \infty$. In this paper we show that this property of collapse models can be modified: we propose a model of spontaneous wavefunction collapse sharing all most important features of usual models but such that the energy of isolated systems reaches an asymptotic finite value instead of increasing with a steady rate.Comment: 14 pages, revtex, no figure

Structure from motion systems for architectural heritage. A survey of the internal loggia courtyard of Palazzo dei Capitani, Ascoli Piceno, Italy

We present the results of a point-cloud-based survey deriving from the use of image-based techniques, in particular with multi-image monoscopic digital photogrammetry systems and software, the so-called “structure-from-motion” technique. The aim is to evaluate the advantages and limitations of such procedures in architectural surveying, particularly in conditions that are “at the limit”. A particular case study was chosen: the courtyard of Palazzo dei Capitani del Popolo in Ascoli Piceno, Italy, which can be considered the ideal example due to its notable vertical, rather than horizontal, layout. In this context, by comparing and evaluating the different results, we present experimentation regarding this single case study with the aim of identifying the best workflow to realise a complex, articulated set of representations—using 3D modelling and 2D processing—necessary to correctly document the particular characteristics of such an architectural object

The Image as a Communication Tool for Virtual Museums. Narration and the Enjoyment of Cultural Heritage

The challenge of contemporary museums is to make content accessible to a wider audience; in this way information related to the good becomes more communicative and usable in order to enhance its uniqueness. Accessibility goes through an innovative communication of content: the Information and Communication Technologies (ICT) that are increasingly part of people’s daily lives. Communication in most cases occurs visually, so ICTs are increasingly focusing on a rethinking of this expressive form; images become a better support for high-quality data transfer

Towards Quantum Superpositions of a Mirror: an Exact Open Systems Analysis - Calculational Details

We give details of calculations analyzing the proposed mirror superposition experiment of Marshall, Simon, Penrose, and Bouwmeester within different stochastic models for state vector collapse. We give two methods for exactly calculating the fringe visibility in these models, one proceeding directly from the equation of motion for the expectation of the density matrix, and the other proceeding from solving a linear stochastic unravelling of this equation. We also give details of the calculation that identifies the stochasticity parameter implied by the small displacement Taylor expansion of the CSL model density matrix equation. The implications of the two results are briefly discussed. Two pedagogical appendices review mathematical apparatus needed for the calculations.Comment: 9 pages, LaTeX. Minor changes mad

Localization and interactions in topological and non-topological bands in two dimensions

A two-dimensional electron gas in a high magnetic field displays macroscopically degenerate Landau levels, which can be split into Hofstadter subbands by means of a weak periodic potential. By carefully engineering such a potential, one can precisely tune the number, bandwidths, bandgaps and Chern character of these subbands. This allows a detailed study of the interplay of disorder, interaction and topology in two dimensional systems. We first explore the physics of disorder and single-particle localization in subbands derived from the lowest Landau level, that nevertheless may have a topological nature different from that of the entire lowest Landau level. By projecting the Hamiltonian onto subbands of interest, we systematically explore the localization properties of single-particle eigenstates in the presence of quenched disorder. We then introduce electron-electron interactions and investigate the fate of many-body localization in subbands of varying topological character