19 research outputs found
Platinum Priority -Urothelial Cancer A Randomized Prospective Trial to Assess the Impact of Transurethral Resection in Narrow Band Imaging Modality on Non-Muscle-Invasive Bladder Cancer Recurrence
PIANO DI GESTIONE DEL SITO UNESCO VILLA ROMANA DEL CASALE
An effective asset management system must consider three essential elements, namely a reference legal framework that defines the reasons for its very existence, an institution that shapes organizational and decision-making needs and resources, human, financial and intellectual, used to make it operational. Having clarified the areas and the meaning of these three decisive elements, it becomes easier to plan, implement and monitor the actions identified to ensure the conservation and management of the assets and values associated with them in a sustainable way.
The management systems are aimed at achieving results that benefit the site and its stakeholders and include planning, implementation and monitoring cycles, aimed at carrying out activities aimed at conservation, interpretation and access to the site, also taking care of the sustainable use and sharing of benefits. Obviously each management system must be regularly reviewed and updated in order to respond to changes in the site and in the context, making the necessary adjustments.
With the powerful work undertaken by Civita to update the three Management Plans of the UNESCO sites of "val di Noto", "Siracusa and the Necropolis of Pantalica" and "villa romana del Casale" of Piazza Armerina, the goal was to develop an integrated system of the three different floors, related to three different contiguous sites, which has no precedent. From this unprecedented and extraordinary coordination it will be possible to reap mutual benefits, economies of scale and common strategies, for example, linked to the unpredictability of the risk of natural disasters or fluctuations in financial resources.
Particular emphasis must be given to the participatory approach used in the drafting of the three Management Plans, through the shared understanding of the site, and its identity, by all interested parties with their involvement in the construction of technical contributions that is premised on involvement in management processes and also foundations- efficiency in terms of reactivity that only the continuous exchange of results and outputs can ensure, feeding the monitoring and reprogramming phases
Protocol of the Italian Radical Cystectomy Registry (RIC): a non-randomized, 24-month, multicenter study comparing robotic-assisted, laparoscopic, and open surgery for radical cystectomy in bladder cancer
Bladder cancer is the ninth most common type of cancer worldwide. In the past, radical cystectomy via open surgery has been considered the gold-standard treatment for muscle invasive bladder cancer. However, in recent years there has been a progressive increase in the use of robot-assisted laparoscopic radical cystectomy. The aim of the current project is to investigate the surgical, oncological, and functional outcomes of patients with bladder cancer who undergo radical cystectomy comparing three different surgical techniques (robotic-assisted, laparoscopic, and open surgery). Pre-, peri- and post-operative factors will be examined, and participants will be followed for a period of up to 24\u2009months to identify risks of mortality, oncological outcomes, hospital readmission, sexual performance, and continence
Protocol of the Italian Radical Cystectomy Registry (RIC): a non-randomized, 24-month, multicenter study comparing robotic-assisted, laparoscopic, and open surgery for radical cystectomy in bladder cancer
Background: Bladder cancer is the ninth most common type of cancer worldwide. In the past, radical cystectomy via open surgery has been considered the gold-standard treatment for muscle invasive bladder cancer. However, in recent years there has been a progressive increase in the use of robot-assisted laparoscopic radical cystectomy. The aim of the current project is to investigate the surgical, oncological, and functional outcomes of patients with bladder cancer who undergo radical cystectomy comparing three different surgical techniques (robotic-assisted, laparoscopic, and open surgery). Pre-, peri- and post-operative factors will be examined, and participants will be followed for a period of up to 24 months to identify risks of mortality, oncological outcomes, hospital readmission, sexual performance, and continence.
Methods: We describe a protocol for an observational, prospective, multicenter, cohort study to assess patients affected by bladder neoplasms undergoing radical cystectomy and urinary diversion. The Italian Radical Cystectomy Registry is an electronic registry to prospectively collect the data of patients undergoing radical cystectomy conducted with any technique (open, laparoscopic, robotic-assisted). Twenty-eight urology departments across Italy will provide data for the study, with the recruitment phase between 1st January 2017-31st October 2020. Information is collected from the patients at the moment of surgical intervention and during follow-up (3, 6, 12, and 24 months after radical cystectomy). Peri-operative variables include surgery time, type of urinary diversion, conversion to open surgery, bleeding, nerve sparing and lymphadenectomy. Follow-up data collection includes histological information (e.g., post-op staging, grading, and tumor histology), short- and long-term outcomes (e.g., mortality, post-op complications, hospital readmission, sexual potency, continence etc).
Discussion: The current protocol aims to contribute additional data to the field concerning the short- and long-term outcomes of three different radical cystectomy surgical techniques for patients with bladder cancer, including open, laparoscopic, and robot-assisted. This is a comparative-effectiveness trial that takes into account a complex range of factors and decision making by both physicians and patients that affect their choice of surgical technique.
Trial registration: ClinicalTrials.gov , NCT04228198 . Registered 14th January 2020- Retrospectively registered
Inclusion of the buoyancy forces in the Incompressible Schrödinger Flow algorithm to simulate inviscid fluids
In 1927, Erwin Madelung developed an analogy between hydrodynamics and the quantum mechanics world by linking wave functions and the velocity of inviscid fluids by a suitable coordinate transformation; in particular, a wave function satisfying a Schrödinger equation results in an associated velocity field compliant with the Euler equations for inviscid flows. Thus, Euler fluids can be numerically simulated with this method, lowering the computational complexity associated with the direct solution of the Euler equations through the Madelung transform under the name of Incompressible Schrödinger Flow (ISF). This work extends the framework of ISF implemented by the authors within a Finite Element framework to adopt the velocity to the advection-diffusion of passive scalars (such as temperature or concentration) and to include, at the 'quantum' level, buoyancy forces in the Schrödinger equation, assuming a Boussinesq-like approximation. This work sets up a simple case study to investigate the relation between wave function and velocity, showing how wave properties reflect in the fluid dynamics world and how temperature gradients can influence the wave functions through linear potential terms, which correspond to buoyancy forces
Non-secreting adrenal myelolipoma in a middle-aged male patient manifesting with sudden onset of severe lower back pain
Adrenal myelolipoma (AML) is a rare benign tumor, usually non-functioning and asymptomatic until it reaches large size. AML is mostly detected incidentally by imaging and is composed of adipose tissue and hematopoietic elements. Only symptomatic tumor needs surgical excision. We report the case of a large non-functioning adrenal tumor discovered by means of combined imaging techniques in a middle-aged male patient who complained the sudden onset of severe lower back pain; successful laparoscopic removal was performed, and AML was diagnosed at histopathology.</jats:p
Bipolar Transurethral Resection in Saline (TURis<sup>®</sup>): Outcome and Complication Rates After the First 1000 Cases
A Randomized Prospective Trial to Assess the Impact of Transurethral Resection in Narrow Band Imaging Modality on Non–Muscle-Invasive Bladder Cancer Recurrence
Digital takes command Orizzonti di progettazione e produzione digitale Design horizons and digital fabrication
Digital Takes Command è un’iniziativa che illustra gli orizzonti della progettazione e produzione digitale avanzata di processi e sistemi di fabbricazione, materiali e componenti di manifattura e costruzione, composta da: una mostra su progetto e produzione digitale di testo e immagini, disegni, fotografie, modelli, audiovisivi, dal titolo: Digitalizzare il reale dal mondo industriale all'industria globale, che propone una riflessione aperta su presupposti e strumenti dell'iniziativa, a cura di Giulio Barazzetta, Enrico Morteo, Alberto Saibene; un Laboratorio Integrato di prototipazione e produzione digitale, che pratica esperienze di: progettazione computazionale e produzione robotica, componenti e sistemi, a cura di Pierpaolo Ruttico - Indexlab e di produzione personalizzata e computazione materica, a cura di Ingrid Paoletti - Actlab; una mostra fotografica sui luoghi e sugli spazi industriali a Lecco dal titolo: Lecco luogo della produzione, il contesto del mondo industriale, a cura di Marco Introini
