723 research outputs found
An atlas of the growth, mortality and recruitment of Philippine fishes
Growth, Mortality, Recruitment, Size distribution, Population dynamics, Fishery biology, Stock assessment, Length, Philippines, Teleostei
Regulating religious robots: free exercise and RFRA in the time of superintelligent artificial intelligence
Philippine Sports Torts: Adopting a Standard of Care for Sports Competitions and Establishing Vicarious Liability for Professional Coaches
Pretreatment of a Soft Soil by Surcharging - A Case History
A normally consolidated silty clay deposit, varying in depth from 0 to 15 m, was pretreated by surcharging combined with P.V.C. vertical drains. Representative field values of the vertical coefficients of primary (0.0015 m2/kN) and secondary consolidation (0.01) were calculated from the settlements caused by a preliminary fill placed some six years prior to the detailed geotechnical studies. A conservative representative field value of the horizontal coefficient of primary consolidation was established to be 8 m2/year. Asaoka\u27s method was used to predict future settlements due to both primary and secondary consolidation. The vertical drains were installed at a spacing of 1.8 musing a modified crawler crane. The average daily output was 158 drains over 128 working days with an average cycle time per pair of drains of eight minutes. The total cost was (A) 3.23 per square metre of the area treated. Surcharging decreased the settlements due to primary and secondary consolidation. Calculated values of settlement over a 10 year period were 80 mm for a 15 m deposit with 50 mm being contributed by secondary consolidation
A novel polymorphism in the 1A promoter region of the vitamin D receptor is associated with altered susceptibilty and prognosis in malignant melanoma
Participation in thrill-seeking activities by patients with hypertrophic cardiomyopathy: Individual preferences, adverse events and physician attitude
Improvement of a clayey soil with alkali activated low-calcium fly ash for transport infrastructures applications
The improvement of geotechnical properties is often achieved by the addition of traditional binders, such as cement or lime. However, the use of such binders implies a considerable financial and environmental cost that needs to be mitigated. An unconventional solution, similar to cement in terms of performance but more environmentally friendly, consists in the use of binders made from alkaline activated industrial residues. The technique consists on the activation of raw materials (such as fly ash or blast furnace slag) rich in Si, Al, or even Ca, with high pH alkaline solutions. The present work was developed aiming the possible stabilisation, using different fly ash contents, of a clayey soil with sand. The activator solution was composed of sodium hydroxide and sodium silicate. The extended experimental campaign included unconfined compressive strength (UCS), California Bearing Ratio (CBR), pulse velocity tests and triaxial tests to assess the geomechanical improvement induced by the new binder. As a mean of comparison, the experimental campaign included also the stabilisation of the same soil with either cement or lime. The obtained data indicates that the use of alkaline activation as a soil stabilisation technique provides competitive geomechanical results, when compared with those obtained with traditional binders.(undefined
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Tobacco smoking, polymorphisms in carcinogen metabolism enzyme genes, and risk of localized and advanced prostate cancer: results from the California Collaborative Prostate Cancer Study
The relationship between tobacco smoking and prostate cancer (PCa) remains inconclusive. This study examined the association between tobacco smoking and PCa risk taking into account polymorphisms in carcinogen metabolism enzyme genes as possible effect modifiers (9 polymorphisms and 1 predicted phenotype from metabolism enzyme genes). The study included cases (n = 761 localized; n = 1199 advanced) and controls (n = 1139) from the multiethnic California Collaborative Case–Control Study of Prostate Cancer. Multivariable conditional logistic regression was performed to evaluate the association between tobacco smoking variables and risk of localized and advanced PCa risk. Being a former smoker, regardless of time of quit smoking, was associated with an increased risk of localized PCa (odds ratio [OR] = 1.3; 95% confidence interval [CI] = 1.0–1.6). Among non-Hispanic Whites, ever smoking was associated with an increased risk of localized PCa (OR = 1.5; 95% CI = 1.1–2.1), whereas current smoking was associated with risk of advanced PCa (OR = 1.4; 95% CI = 1.0–1.9). However, no associations were observed between smoking intensity, duration or pack-year variables, and advanced PCa. No statistically significant trends were seen among Hispanics or African-Americans. The relationship between smoking status and PCa risk was modified by the CYP1A2 rs7662551 polymorphism (P-interaction = 0.008). In conclusion, tobacco smoking was associated with risk of PCa, primarily localized disease among non-Hispanic Whites. This association was modified by a genetic variant in CYP1A2, thus supporting a role for tobacco carcinogens in PCa risk
A systematic review investigating fatigue, psychological and cognitive impairment following TIA and minor stroke:protocol paper
Approximately 20,000 people have a transient ischemic attack (TIA) and 23,375 have a minor stroke in England each year. Fatigue, psychological and cognitive impairments are well documented post-stroke. Evidence suggests that TIA and minor stroke patients also experience these impairments; however, they are not routinely offered relevant treatment. This systematic review aims to: (1) establish the prevalence of fatigue, anxiety, depression, post-traumatic stress disorder (PTSD) and cognitive impairment following TIA and minor stroke and to investigate the temporal course of these impairments; (2) explore impact on quality of life (QoL), change in emotions and return to work; (3) identify where further research is required and to potentially inform an intervention study
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