Nitrogen loss (NH3, N2O) patterns in bench-scale composting.

Nitrogen (N) losses during composting reduce the value of the end product as a fertilizer. Nitrogen is lost during composting mainly by ammonia (NH3) volatilization in the thermophilic phase. We used three bench-scale aerobic bioreactors with a controlled temperature difference (CDT) system as an experimental approach to investigate the pattern of N losses during composting. N2O peak emission occurred much earlier (7h) than NH3 volatilization (48-60h) during the thermophilic phase (~55°C) of bench-scale composting. The NH3 volatilization peak rate occurred following the greater biological activity (O2 consumed/CO2 evolved) at 40°C which could coincide with greater ammonification, but immobilization of NH4+/NH3 also occurs at this point affecting NH3 volatilization. Differences in temperature curves and accumulated NH3-N were related to the biological activity in each vessel. Therefore, O2 consumed/CO2 evolved measurements must be part of the evaluation of composting in further studies for comparisons of techniques to reduce NH3 volatilizatio

The application of local hypobaric pressure — A novel means to enhance macromolecule entry into the skin

AbstractThe local application of controlled hypobaric stress represents a novel means to facilitate drug delivery into the skin. The aims of this work were to understand how hypobaric stress modified the properties of the skin and assess if this penetration enhancement strategy could improve the percutaneous penetration of a macromolecule. Measurements of skin thickness demonstrated that the topical application of hypobaric stress thinned the tissue (p<0.05), atomic force microscopy showed that it shrunk the corneocytes in the stratum corneum (p<0.001) and the imaging of the skin hair follicles using multiphoton microscopy showed that it opened the follicular infundibula (p<0.001). Together, these changes contributed to a 19.6-fold increase in in vitro percutaneous penetration of a 10,000 molecular weight dextran molecule, which was shown using fluorescence microscopy to be localized around the hair follicles, when applied to the skin using hypobaric stress. In vivo, in the rat, a local hemodynamic response (i.e. a significant increase in blood flow, p<0.001) was shown to contribute to the increase in follicular transport of the dextran to produce a systemic absorption of 7.2±2.81fg·mL−1. When hypobaric stress was not applied to the rat there was no detectable absorption of dextran and this provided evidence that this novel penetration enhancement technique can improve the percutaneous penetration of macromolecules after topical application to the skin

Tatu-Bolinha (artrópodo, gênero Armadillium) como ferramenta de ecoalfabetização.

A cultura ocidental promove o distanciamento dos fundamentos ecológicos, o que gera desequilíbrios como os decorrentes da substituição das funções ecológicas da biodiversidade pelos agrotóxicos. Os relatos apresentados proveem de atividades de Educação Ambiental com ênfase na ecoalfabetização, desenvolvidas à partir de 2005, em Sete Lagoas, MG. O Projeto de Ecoalfabetização Tatu Bolinha foi idealizado para ampliar a discussão relativa à biodiversidade em curso de formação de professores de Geografia nas Faculdades UNIFEMM. Foram desenvolvidos trabalhos relativos à absorção de água pelas fezes do tatu-bolinha, resgate de convivência com a biodiversidade, contação de história, história em quadrinho, matéria ilustrada no "Jornal do Manuelzão", projeto pedagógico com terráreo, ferramenta no Programa Embrapa & Escola e teatro de bonecos. A fundamentação ecológica é ferramenta para contribuir com a transição da cultura antropocêntrica por uma cultura que incorpore as leis naturais e valorize a diversidade

Does bariatric surgery prior to total hip or knee arthroplasty reduce post-operative complications and improve clinical outcomes for obese patients? Systematic review and meta-analysis.

AIMS: Our aim was to determine whether, based on the current literature, bariatric surgery prior to total hip (THA) or total knee arthroplasty (TKA) reduces the complication rates and improves the outcome following arthroplasty in obese patients. METHODS: A systematic literature search was undertaken of published and unpublished databases on the 5 November 2015. All papers reporting studies comparing obese patients who had undergone bariatric surgery prior to arthroplasty, or not, were included. Each study was assessed using the Downs and Black appraisal tool. A meta-analysis of risk ratios (RR) and 95% confidence intervals (CI) was performed to determine the incidence of complications including wound infection, deep vein thrombosis (DVT), pulmonary embolism (PE), revision surgery and mortality. RESULTS: From 156 potential studies, five were considered to be eligible for inclusion in the study. A total of 23 348 patients (657 who had undergone bariatric surgery, 22 691 who had not) were analysed. The evidence-base was moderate in quality. There was no statistically significant difference in outcomes such as superficial wound infection (relative risk (RR) 1.88; 95% confidence interval (CI) 0.95 to 0.37), deep wound infection (RR 1.04; 95% CI 0.65 to 1.66), DVT (RR 0.57; 95% CI 0.13 to 2.44), PE (RR 0.51; 95% CI 0.03 to 8.26), revision surgery (RR 1.24; 95% CI 0.75 to 2.05) or mortality (RR 1.25; 95% CI 0.16 to 9.89) between the two groups. CONCLUSION: For most peri-operative outcomes, bariatric surgery prior to THA or TKA does not significantly reduce the complication rates or improve the clinical outcome. This study questions the previous belief that bariatric surgery prior to arthroplasty may improve the clinical outcomes for patients who are obese or morbidly obese. This finding is based on moderate quality evidence. Cite this article: Bone Joint J 2016;98-B:1160-6

Prevalence of eye conditions, utilization of eye health care services, and ophthalmic medications after entering residential aged care in Australia

Purpose This study aims to evaluate the burden and trends of eye diseases, utilisation of eye health care services, and ophthalmic medications among older people living in residential aged care facilities in Australia. Methods A cross-sectional study was conducted using data from the Registry of Senior Australians. Individuals aged ≥65 years who entered permanent residential aged care facilities between 2008 and 2015 were included. The prevalence (95% confidence interval [CI]) of eye diseases by year, eye health care services, and ophthalmic medication use within a year of entry into the service were evaluated. Poisson regression models estimated adjusted rate of change using prevalence ratio (PR) by age, sex, state, and frailty scores. Results Of the 409,186 people studied, 43.6% (N = 178,367) had an eye condition. Of the total cohort, 32.9% (N = 134,566) had chronic eye conditions and 19.7% (N = 80,661) had an acute eye condition. Common chronic eye conditions were glaucoma (13.6%, N = 55,830), cataract (8%, (N = 32,779), blindness (4.5%, N = 18,856), and poor vision (10.3%, N = 42,245). Prevalence of any eye condition (2008: 42.7%, 95% CI = 42.2%-43.2% and 2015: 41.2%, 95% CI = 40.8-41.6%, PR = 0.99, 95% CI = 0.99-0.99, P ConclusionsThe prevalence of blindness among older Australian using residential aged care services decreased over the study period. However, the burden of eye diseases remained high between 2008 and 2015, whereas the use of eye health care services was disproportionately low. This study provides evidence of a significant need for eye health care services for older people with an eye disease in residential aged care facilities. Translational relevance Four in ten long term aged care residents in Australia had at least one eye condition over the study period, indicating potential for a high eye health care needs in aged care settings.Jyoti Khadka, Julie Ratcliffe, Gillian E. Caughey, Steve L.Wesselingh and Maria C. Inaci

Challenges to Domesticating Native Forage Legumes

If ruminant production from cultivated and natural grasslands is to depend less on petroleum-based products, forage legumes must serve as protein sources. Commercially available legumes for warm-dry climate grasslands are, however, very limited and resources available for developing such legumes are inadequate. Indeterminate flowering and dehiscent seed pods combined with the need for specialized seed harvesting equipment are major impediments (Butler and Muir 2012). Warm climates often present environmental challenges such as poor rainfall distribution, extended dry seasons, temperature extremes and aggressive grass species (Muir et al. 2011). Erosion of indigenous knowledge and replacement with inappropriate land management approaches from moist-temperate regions compound the challenges

Autocalibration of accelerometer data for free-living physical activity assessment using local gravity and temperature: an evaluation on four continents.

Wearable acceleration sensors are increasingly used for the assessment of free-living physical activity. Acceleration sensor calibration is a potential source of error. This study aims to describe and evaluate an autocalibration method to minimize calibration error using segments within the free-living records (no extra experiments needed). The autocalibration method entailed the extraction of nonmovement periods in the data, for which the measured vector magnitude should ideally be the gravitational acceleration (1 g); this property was used to derive calibration correction factors using an iterative closest-point fitting process. The reduction in calibration error was evaluated in data from four cohorts: UK (n = 921), Kuwait (n = 120), Cameroon (n = 311), and Brazil (n = 200). Our method significantly reduced calibration error in all cohorts (P 0.05). Temperature correction coefficients were highest for the z-axis, e.g., 19.6-mg offset per 5°C. Further, application of the autocalibration method had a significant impact on typical metrics used for describing human physical activity, e.g., in Brazil average wrist acceleration was 0.2 to 51% lower than uncalibrated values depending on metric selection (P < 0.01). The autocalibration method as presented helps reduce the calibration error in wearable acceleration sensor data and improves comparability of physical activity measures across study locations. Temperature ultization seems essential when temperature deviates substantially from the average temperature in the record but not for multiday summary measures.This is the final version of the article. It first appeared from the American Physiological Society via http://dx.doi.org/10.1152/japplphysiol.00421.201