1,209 research outputs found

    Khat: current views from the community around the UK - Findings from Communtiy Engagement Forums

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    Partial Stroke Test For Emergency Shutdown Valve Masoneilan: Analysis Of Design And Verification Using Aft Fathom Software

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    This report will present the process of testing of the controller for Partial Stroke Test (PST) system provided by vendors and to perform Full Stroke Test (FST) using Programmable logic Controller (PLC)

    Clinical and etiological profile of neonatal seizures: a tertiary care hospital based study

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    Background: The most vulnerable period of life to develop seizures is the neonatal period. These events very often signify serious damage or malfunction of the immature developing central nervous system. Neonatal seizures may arise as a result of diverse etiologies and can have varied presentations. Objective: Our study was aimed at finding the incidence, etiological factors, and time of onset, clinical types and various biochemical abnormalities in neonatal seizures.Methods: A hospital based prospective observational study was undertaken in a tertiary care paediatric hospital of Government Medical College Srinagar. A total of 100 consecutive neonates presenting with seizures from September 2013 to August 2014 were enrolled in the study. Detailed antenatal history and baseline characteristics of convulsing neonate were recorded at admission. Clinical details of each seizure episode reported by the mother and subsequently observed by the resident doctors on duty were recorded. Venous blood was collected as soon as possible and blood glucose, total serum calcium levels, Na+, K+, Mg and P-levels were done immediately after baby had seizures and before instituting any treatment. Data was described as mean ± SE and %age. SPSS 16.0 and MS Excel software were used for data analysis.Results: Cumulative frequency of 3.9% was recorded in neonatal seizures in our setup. Hypoxic ischemic encephalopathy was the commonest etiology of neonatal seizures. Intracranial haemorrhage followed by Hypoxic ischemic encephalopathy was the commonest seizure etiology in preterm neonates. Majority of Hypoxic ischemic encephalopathy patients presented with seizures in the first 72 hrs. of life. Focal clonic and subtle seizures were the commonest seizure types encountered. 17 neonates (31%) had primary metabolic seizures. Hypocalcaemia was the commonest biochemical abnormality in primary metabolic seizures and was present in 70% neonates in this group. Hypoglycaemia was the next commonest abnormality and was present in 41% neonates within this group.Conclusions: Hypoxic ischemic encephalopathy was the commonest etiology with focal clonic and subtle seizures being the commonest clinical types encountered. Hypocalcaemia was the most frequent biochemical abnormality found.

    Spontaneous rupture of pyonephrosis leading to pyoperitoneum

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    Forniceal rupture after pyonephrosis can lead to retroperitoneal abscess but extension into peritoneal cavity is unusual. We present a case of 50 year old lady who presented with acute abdomen, CT scan of abdomen showed features suggestive of left pyelonephritis and large intraperitoneal collection. Laparotomy was planned on suspicion of intraperitoneal source of sepsis. Peroperatively no intraperitoneal source of sepsis was found. Retrograde pyelography showed forniceal rupture at lower pole of kidney extending to peritoneal cavity without any obstructing stone or lesion. This case highlights an unusual presentation of pyonephrosis with peritonitis and pyoperitoneum

    Partial Stroke Test For Emergency Shutdown Valve Masoneilan: Analysis Of Design And Verification Using Aft Fathom Software

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    This report will present the process of testing of the controller for Partial Stroke Test (PST) system provided by vendors and to perform Full Stroke Test (FST) using Programmable logic Controller (PLC)

    Geotechnical characteristics of effluent contaminated cohesive soils

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    In developing countries like Pakistan, raw industrial effluents are usually disposed-off directly into open lands or in water bodies resulting in soil contamination. Leachate formation due to rainfalls in openly dumped solid waste also adds to soil contamination. In this study, engineering behavior of soils contaminated by two industrial effluents, one from paper industry (acidic) and another from textile industry (basic), has been investigated. Laboratory testing revealed significant effects of effluent contamination on engineering behavior of tested soils. Liquid limit, plasticity index, optimum moisture content and compression index of tested soils were found to increase with effluent contaminant, indicating a deterioration in the engineering behavior of soils. Whereas maximum dry density, undrained shear strength and coefficient of consolidation of the contaminated soils showed a decreasing trend. The dilapidation in engineering characteristics of soils due to the addition of industrial effluents could pose serious threats to existing and future foundations in terms of loss of bearing capacity and increase in settlement. Keywords: soil contamination, industrial waste, engineering behavior, effluent waste, leachate. First published online: 28 Nov 201

    Assessment of medication adherence and factors contributing to non-adherence to calcium and vitamin D as mainstay in treatment and prophylaxis of osteoporosis.

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    Objective: This study aimed to assess the adherence and persistence to Calcium and vitamin D, and address the reasons of non-adherence. Methods: All patients attending a secondary care rheumatology clinic in a teaching hospital serving a multiethnic population, in the period between April and June fulfill the inclusion criteria. Patients were asked verbally before distributing the question air about the duration and reason of prescribed Calcium and vitamin D, only patients who are receiving Calcium and Vitamin D for duration of one year or more for purpose of osteoporosis management (treatment and prophylaxis) and are welling to participate in the question are were given the consent formand included in the study. Key finding: There was no statistically significant difference between calcium and vitamin D group in terms of adherence score (p = 0.175). About third of patients in both groups showed low adherence score; 31% (53/171), 38.2% (128/335) in calcium and vitamin D groups, respectively. Overall, there was significant difference in adherence score between age groups (p = 0.001). Low adherence score was mostly reported in young age group (18–39 years) for both medications but not related to level of education. Forget to take medication was the most reported reason of non adherence in both groups (29.5%, 89/302). Quarter of patients stated that multi-reasons contributed to their non adherence (24.8%, 75/302). Conclusion: Low adherence was high among both Calcium and Vitamin D groups (around third of both groups), however; there were no significant differences in medications adherence between the two groups
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