Measurement properties of the German version of the IKDC subjective knee form (IKDC-SKF).

PURPOSE: To examine the measurement properties of the German International Knee Documentation Committee Subjective Knee Form (IKDC-SKF) in knee disorder patients. METHODS: Three hundred twelve consecutive patients undergoing surgery for anterior cruciate ligament, meniscus and/or cartilage injuries completed the IKDC-SKF, Lysholm Score, Tegner Activity Scale, and Short Form-12 Health Survey before and 6 months post-surgery. IKDC-SKF measurement properties were calculated and patients were also asked to rate the relevance/comprehensibility of the questionnaire items. RESULTS: Reliability was good with high Cronbach's alpha and intraclass correlation coefficients, and standard error of measurement values of 4.4 to 6.0. The smallest detectable change (SDC) ranged from 12.3 to 16.7 points. Validity was good with 90% of all hypotheses confirmed. Confirmatory factor analysis did not show adequate fitting indices within the model. Over half of the items were rated as essential, and all were well comprehended. The majority of hypotheses for responsiveness were confirmed. No floor and ceiling effects were observed. The area under the curve ranged from 0.82 to 0.89 and the minimal important difference was smaller than the SDC. CONCLUSIONS: The German IKDC-SKF is a reliable outcome measure with good hypotheses testing and responsiveness, but its MIC and structural/content validity need further analysis

On carbon and oxygen isotope ratios in starburst galaxies: New data from NGC253 and Mrk231 and their implications

Using the IRAM 30-m telescope, CN and CO isotopologues have been measured toward the central regions of the nearby starburst galaxy NGC253 and the prototypical ultraluminous infrared galaxy Mrk231. In NGC253, the 12C/13C ratio is 40+-10. Assuming that the ratio also holds for the CO emitting gas, this yields 16O/18O = 145+-36 and 16O/17O = 1290+-365 and a 32S/34S ratio close to that measured for the local interstellar medium (20-25). No indication for vibrationally excited CN is found. Peak line intensity ratios between NGC253 and Mrk231 are ~100 for 12C16O and 12C18O J=1-0, while the ratio for 13C16O J=1-0 is ~250. This and similar 13CO and C18O line intensities in the J=1-0 and 2-1 transitions of Mrk231 suggest 12C/13C ~ 100 and 16O/18O ~ 100, in agreement with values obtained for the less evolved ultraluminous merger Arp220. Also accounting for other extragalactic data, 12C/13C ratios appear to vary over a full order of magnitude, from >100 in ultraluminous high redshift galaxies to ~100 in more local such galaxies to ~40 in weaker starbursts not undergoing a large scale merger to 25 in the Central Molecular Zone of the Milky Way. With 12C being predominantly synthesized in massive stars, while 13C is mostly ejected by longer lived lower mass stars at later times, this is qualitatively consistent with our results of decreasing carbon isotope ratios with time and rising metallicity. It is emphasized, however, that both infall of poorly processed material, initiating a nuclear starburst, as well as the ejecta from newly formed massive stars (in particular in case of a top-heavy stellar initial mass function) can raise the carbon isotope ratio for a limited amount of time.Comment: Accepted by Astronomy & Astrophysics, 6 figures, 4 table

ALLSMOG: an APEX Low-redshift Legacy Survey for MOlecular Gas. I - molecular gas scaling relations, and the effect of the CO/H2 conversion factor

We present ALLSMOG, the APEX Low-redshift Legacy Survey for MOlecular Gas. ALLSMOG is a survey designed to observe the CO(2-1) emission line with the APEX telescope, in a sample of local galaxies (0.01 < z < 0.03), with stellar masses in the range 8.5 < log(M*/Msun) < 10. This paper is a data release and initial analysis of the first two semesters of observations, consisting of 42 galaxies observed in CO(2-1). By combining these new CO(2-1) emission line data with archival HI data and SDSS optical spectroscopy, we compile a sample of low-mass galaxies with well defined molecular gas masses, atomic gas masses, and gas-phase metallicities. We explore scaling relations of gas fraction and gas consumption timescale, and test the extent to which our findings are dependent on a varying CO/H2 conversion factor. We find an increase in the H2/HI mass ratio with stellar mass which closely matches semi-analytic predictions. We find a mean molecular gas fraction for ALLSMOG galaxies of MH2/M* = (0.09 - 0.13), which decreases with stellar mass. We measure a mean molecular gas consumption timescale for ALLSMOG galaxies of 0.4 - 0.7 Gyr. We also confirm the non-universality of the molecular gas consumption timescale, which varies (with stellar mass) from ~100 Myr to ~2 Gyr. Importantly, we find that the trends in the H2/HI mass ratio, gas fraction, and the non-universal molecular gas consumption timescale are all robust to a range of recent metallicity-dependent CO/H2 conversion factors.Comment: 25 pages, 15 figures. Accepted for publication in MNRA

Hip muscle weakness in patients with symptomatic femoroacetabular impingement

SummaryObjectiveFemoroacetabular impingement (FAI) is a pathomechanical process, which may cause hip pain, disability and early development of hip osteoarthritis (OA) in young and active adults. Patients with FAI experience functional disability during dynamic weight-bearing activities, which could originate from weakness of the hip muscles. The objective of this study was to compare hip muscle strength between patients with symptomatic FAI and healthy controls. It was hypothesized that patients would present overall hip muscle weakness compared to controls.MethodsA total of 22 FAI patients and 22 controls matched for gender, age, and body mass participated in the study. We evaluated isometric maximal voluntary contraction (MVC) strength of all hip muscle groups using hand-held and isokinetic dynamometry, and electromyographic (EMG) activity of the rectus femoris (RF) and tensor fasciae latae (TFL) muscles during active flexion of the hip.ResultsFAI patients had significantly lower MVC strength than controls for hip adduction (28%), flexion (26%), external rotation (18%) and abduction (11%). TFL EMG activity was significantly lower in FAI patients compared with controls (P=0.048), while RF EMG activity did not differ significantly between the two groups (P=0.056).ConclusionsPatients with symptomatic FAI presented muscle weakness for all hip muscle groups, except for internal rotators and extensors. Based on EMG recordings, it was demonstrated that patients with symptomatic FAI have a reduced ability to activate TFL muscle during hip flexion. These findings provide orthopedic surgeons with objective information about the amount and specificity of hip muscle weakness in patients with FAI. Future research should investigate the relationship between hip muscle weakness, functional disability and overuse injury risks, as well as the effects of hip muscle strengthening on clinical outcomes in individuals with symptomatic FAI

ALMA Observations of the Physical and Chemical Conditions in Centaurus A

Centaurus A, with its gas-rich elliptical host galaxy, NGC 5128, is the nearest radio galaxy at a distance of 3.8 Mpc. Its proximity allows us to study the interaction between an active galactic nucleus, radio jets, and molecular gas in great detail. We present ALMA observations of low J transitions of three CO isotopologues, HCN, HCO$^{+}$, HNC, CN, and CCH toward the inner projected 500 pc of NGC 5128. Our observations resolve physical sizes down to 40 pc. By observing multiple chemical probes, we determine the physical and chemical conditions of the nuclear interstellar medium of NGC 5128. This region contains molecular arms associated with the dust lanes and a circumnuclear disk (CND) interior to the molecular arms. The CND is approximately 400 pc by 200 pc and appears to be chemically distinct from the molecular arms. It is dominated by dense gas tracers while the molecular arms are dominated by $^{12}$CO and its rare isotopologues. The CND has a higher temperature, elevated CN/HCN and HCN/HNC intensity ratios, and much weaker $^{13}$CO and C$^{18}$O emission than the molecular arms. This suggests an influence from the AGN on the CND molecular gas. There is also absorption against the AGN with a low velocity complex near the systemic velocity and a high velocity complex shifted by about 60 km s$^{-1}$. We find similar chemical properties between the CND in emission and both the low and high velocity absorption complexes implying that both likely originate from the CND. If the HV complex does originate in the CND, then that gas would correspond to gas falling toward the supermassive black hole

Fluorine effect on As diffusion in Ge

The enhanced diffusion of donor atoms, via a vacancy (V)-mechanism, severely affects the realization of ultrahigh doped regions in miniaturized germanium (Ge) based devices. In this work, we report a study about the effect of fluorine (F) on the diffusion of arsenic (As) in Ge and give insights on the physical mechanisms involved. With these aims we employed experiments in Ge co-implanted with F and As and density functional theory calculations. We demonstrate that the implantation of F enriches the Ge matrix in V, causing an enhanced diffusion of As within the layer amorphized by F and As implantation and subsequently regrown by solid phase epitaxy. Next to the end-of-range damaged region F forms complexes with Ge interstitials, that act as sinks for V and induce an abrupt suppression of As diffusion. The interaction of Ge interstitials with fluorine interstitials is confirmed by theoretical calculations. Finally, we prove that a possible F-As chemical interaction does not play any significant role on dopant diffusion. These results can be applied to realize abrupt ultra-shallow n-type doped regions in future generation of Ge-based devices