The Russian Village, Urban Infrastructure Issues, and the Vertically Integrated Agriculture Model

Russia’s population total has been in decline since 1992 and this is most evident in the villages of Russia. With the collapse of the Soviet Union and the large farm collectives, many villages’ raison d\u27être ceased to exist. Today people continue to leave the villages for what they consider to be the better economic promise of the larger cities. There are serious societal and infrastructure issues related to the village exodus to the larger municipalities. In this paper, a vertically integrated agriculture model is examined as one step towards a more vibrant village economy. A vertically integrated model based upon potatoes is proffered, but this same model could work in many areas of agricultural production

The American Debt Crisis and the Effect on World Capital Markets

This is a research of the literature concerning American sovereign debt and possible effects on world capital markets. The American sovereign debt components were analyzed in the context of their present and future implications to worldwide capital markets. The American political situation was examined with possible outcomes of governmental service reduction and/or tax increases for debt reduction. The American political situation was also examined for possible outcomes of American business tax regulatory reforms that could entice businesses to inject capital into the economy spurring possible economic growth and capital formation. Together, these findings suggest that, in the short term, the lack of political will in America concerning the sovereign debt issue will continue to have negative effects on world capital markets and long term inactivity could lead to more serious issues

Implications to the Traditional Higher Education Model in a Time of New Economic and Demographic Realities

In the world’s developed countries the tendency is to a decreasing or stagnant, aging population. Traditional higher education has occurred early in life with little retraining in adulthood. The current demographic and economic realities demand a change in the role of traditional higher education as it must be more flexible and portable. Higher education must play a central role in the lifelong learning process as new technologies become available. Changes will occur with or without the approval of the established higher education hierarchy as businesses and governments demand quicker, cheaper, and better delivery methods to the current system. Technology is changing at such a rapid pace that the current higher education system must retool as well

Creating Social Capital Though The Deliberative Discussion: A Case Study Of Community Dialogue.

When citizens come together to inquire about issues that matter to the community, learning may occur in these temporary learning communities. Active engagement with issues of social and political importance may increase the adult’s sense of commitment to action and further the development of a community’s social capital. Using a social capital development framework, this case describes one community’s attempt to promote and encourage citizens to engage in deliberative discussion. The case also highlights one citizen’s struggle to link discourse with community action

Creating Self-Awareness Of Learning That Occurs In Community

Learning that occurs in naturally forming communities can be more effective if those who engage in such groups are aware of it. Adult education practitioners who work with groups have an opportunity to assist group participants realize that learning occurs through engagement with issues of importance to them. Adults may consider learning to be knowledge acquisition, but the concept of social capital can be used to help them realize another level of learning. The purpose of this paper is to raise awareness among adult education practitioners about a potential role in furthering learning that occurs in naturally forming groups

OR13-3 Effects of Iron Isomaltoside versus Ferric Carboxymaltose on Hormonal Control of Phosphate Homeostasis: The PHOSPHARE-IDA04/05 Randomized Controlled Trials

Iron isomaltoside (IIM) and ferric carboxymaltose (FCM) are newer intravenous iron preparations that can be administered in high-doses to rapidly correct iron deficiency anemia (IDA). FCM can cause hypophosphatemia due to fibroblast growth factor 23 (FGF23) mediated renal phosphate wasting, which has been associated with osteomalacia, but the comparative effects of IIM are unknown. In two separate, identically designed, open label randomized controlled trials, we 1:1 randomized 245 adults with IDA to receive IIM (single infusion of 1000 mg) or FCM (FDA-approved dosing schedule: 2 infusions of 750 mg administered 1 week apart). We compared the incidence, severity and duration of hypophosphatemia, and effects on renal phosphate excretion, FGF23, PTH, vitamin D, and biomarkers of bone turnover measured in blood and urine samples collected at study visits at baseline (day 0) and on days 1, 7, 8, 14, 21, and 35. In pooled analyses of both trials, the incidence of hypophosphatemia 35 days. FCM but not IIM also induced changes in vitamin D and calcium homeostasis that triggered secondary hyperparathyroidism, which likely contributed to persistence of hypophosphatemia. Consistent with case reports of pathological fractures following FCM use, FCM also induced significant elevations of biomarkers of bone turnover that are associated with osteomalacia

Successful treatment of neonatal severe hyperparathyroidism with cinacalcet in two patients

Neonatal severe hyperparathyroidism (NSHPT) is a rare disorder caused by inactivating calcium-sensing receptor (CASR) mutations that result in life-threatening hypercalcemia and metabolic bone disease. Until recently, therapy has been surgical parathyroidectomy. Three previous case reports have shown successful medical management of NSHPT with cinacalcet. Here we present the detailed description of two unrelated patients with NSHPT due to heterozygous R185Q CASR mutations. Patient 1 was diagnosed at 11 months of age and had developmental delays, dysphagia, bell-shaped chest, and periosteal bone reactions. Patient 2 was diagnosed at 1 month of age and had failure to thrive, osteopenia, and multiple rib fractures. Cinacalcet was initiated at 13 months of age in patient 1, and at 4 months of age in patient 2. We have successfully normalized their parathyroid hormone and alkaline phosphatase levels. Despite the continuance of mild hypercalcemia (11-12 mg/dl), both patients showed no hypercalcemic symptoms. Importantly, patient 1 had improved neurodevelopment and patient 2 never experienced any developmental delays after starting cinacalcet. Neither experienced fractures after starting cinacalcet. Both have been successfully managed long-term without any significant adverse events. These cases expand the current literature of cinacalcet use in NSHPT to five successful reported cases. We propose that cinacalcet may be considered as an option for treating the severe hypercalcemia and metabolic bone disease found in infants and children with inactivating CASR disorders. LEARNING POINTS: NSHPT due to mutations in the CASR gene occurs with hypercalcemia and metabolic bone disease, but not always with severe critical illness in infancy.NSHPT should be considered in the differential diagnosis for a newborn with a bell-shaped chest, osteopenia, and periosteal reactions.Neurodevelopmental consequences may occur in children with hypercalcemia and may improve during treatment.Calcimimetics can be used to successfully treat the pathophysiology of NSHPT directly to control serum calcium levels

The Association Between Discrimination and Sleep is Exacerbated in Individuals with Comorbid Chronic Health Conditions

Introduction: The consequences of recurrent, stressful daily experiences for sleep health appear intensified in individuals with pre-existing health conditions. Although discrimination has been associated with sleep outcomes, the role of comorbid chronic health conditions (CCHCs), and impact of perceived discrimination, remains unclear. The present study investigated (1) the associations between daily discrimination and sleep and (2) moderating roles of CCHCs and daily life interference and hardship. Methods: The current study utilized archival data from the Midlife in the United States (MIDUS) Study II. Participants, 174 adults (51% female, Mage=57 yrs., SD=11.5 yrs.), completed 7 days of actigraphy, sleep diary, PSQI, and CCHC-reporting measures. Models examined the moderating effects of CCHCs, daily interference, and hardship on the association between discrimination and sleep. Results: Daily discriminatory experiences predicted numerous poor sleep outcomes, exacerbated for persons with higher CCHCs. Higher comorbidity (95% CI=5.40, 68.75) exacerbated the association between discrimination and TSTactigraphy, further strengthened by perceived hardship (95% CI=-3.75, -.40) and interference (95% CI=-3.65, -.30). Number of CCHCs, qualified by perceived hardship (95% CI=.00, .04) and interference (95% CI=.01, .05), predicted diary sleep quality above discrimination. The interaction between CCHCs and hardship predicted global PSQI scores (95% CI=-.91, -.12) beyond discrimination. Conclusion: Daily experiences of discrimination are associated with decreased sleep duration and quality. These associations were stronger for individuals with multiple CCHCs. Exacerbating CCHC effects were perpetuated by perceived interference and hardships, suggesting individual emotion regulation (ER) differences. Future research should attend to sleep-related consequences of differential discrimination-informed ER by persons with CCHCs.https://scholarscompass.vcu.edu/gradposters/1042/thumbnail.jp