THE DETERMINANT OF OUTPATIENT HEALTH SERVICES UTILIZATION FOR ELDERLY PATIENT IN INDONESIA (SUSENAS 2017 DATA ANALYSIS)

ABSTRAKIndonesia has entered an aging population as showed by the number of elderly population which has reached more than 7% of the population. Basically, the increase in the elderly population will also increase the number of illnesses, because the more a person ages, the physical condition will decrease and be more susceptible to disease. This research is a quantitative study that aims to determine the determinants of outpatient health service use for Indonesian elderly in 2017. This research used secondary data from the 2017 National Socio-Economic Survey (Susenas) results with the unit of analysis is people aged ≥ 60 years who had health complaints. The analytical method used is logit regression analysis. The results showed that gender, education, employment status, residential area, health insurance ownership, economic status, and disruption of activity due to illness had a p-value of 0,000 < 0,05 which means that it was significantly associated with the utilization of outpatient health services. The most dominant variable is the disruption of activity due to illness. The government can issue policies related to efforts to register each elderly person into health insurance through optimizing a healthy Indonesian program with a family approach. The government is expected to be more assertive in monitoring and evaluating elderly health services by considering factors that support the elderly in utilizing health services to achieve healthy aging and active aging. ABSTRAKIndonesia telah memasuki populasi menua yang ditunjukkan dengan angka populasi lansia yang sudah mencapai angka lebih dari 7% jumlah penduduk. Pada dasarnya kenaikan populasi lansia juga akan meningkatkan angka keluhan kesehatan dan kesakitan, karena semakin bertambah usia seseorang maka kondisi fisiknya akan menurun dan lebih rentan terhadap penyakit. Penelitian ini merupakan penelitian kuantitatif yang bertujuan untuk mengetahui determinan pemanfaatan pelayanan kesehatan rawat jalan pada lansia sakit di Indonesia tahun 2017. Data yang digunakan adalah data sekunder dari hasil Survei Sosial Ekonomi Nasional (Susenas) tahun 2017 dengan unit analisis yaitu individu dengan usia ≥ 60 tahun yang mempunyai keluhan kesehatan. Metode analisis yang digunakan adalah analisis regresi logit. Hasil penelitian menunjukkan bahwa jenis kelamin, pendidikan, status pekerjaan, wilayah tinggal, kepemilikan jaminan kesehatan, status ekonomi, dan gangguan aktivitas akibat sakit mempunyai nilai P-value 0,000 < 0,05 yang berarti berhubungan secara signifikan dengan pemanfaatan pelayanan kesehatan rawat jalan. Pemerintah diharapkan dapat lebih tegas dalam memonitoring serta mengevaluasi pelayanan kesehatan lansia dengan mempertimbangkan faktor yang mendukung lansia dalam memanfaatkan pelayanan kesehatan agar tercapainya healthy ageing dan active ageing

SENYAWA 4-HIDROKSI SINAMAMIDA DARI EKSTRAK ETIL ASETAT (EtOAc) KULIT AKAR PALIASA (Kleinhovia hospita Linn)

Isolation and identification of secondary metabolites from EtOac extract of the root bark of Kleinhovia hospita Linn. plant had been performed. Separation techniques used consisted of extraction, fractionation, and purification. The compounds obtained were tested and elucidated based on UV, IR, and NMR spectroscopy data. A compound obtained was 4-hydroxy cinnamamide

SENYAWA GOLONGAN 2-ARYLBENZOFURAN DAN STILBEN DARI EKSTRAK METILEN KLORIDA (CH2CL2) DAUN Artocarpus fretessi HASSK

Isolation and identification of secondary metabolites from CH2Cl2 extract of the leaves of Artocarpus fretessi Hassk plant had been performed. Separation techniques used consisted of extraction, fractionation, and purification. The classes of compounds obtained were tested and elucidated based on UV and IR spectroscopy data. Two compounds obtained were 2–arylbenzofuran and stilben

PROFIL KIMIA TUMBUHAN PERSEA AMERICANA MILL. INDONESIA

Isolation and identification of secondary metabolites from extract of Persea Americana Mill. Plant had been performed. Separation techniques used consisted of extraction, fractionation, purification, and bioassay used Brin shrimp Lethality Test. The compounds obtained were tested and elucidated based on IR spectroscopy data. The compounds obtained were flavonoid (1) with LC50 = 24,342 μg/mL and alkaloid (2) with LC50 = 39,8 μg/mL

Active Compounds Of Ethyl Acetate Extract Of Stylotella Sp. Sponges From Selayar Islands Against Mcf-7 Breast Cancer Cells

Stylotella sp. sponge is a type of marine invertebrate animals that are widely distributed in Indonesian marine areas. One of the spreading areas of the Stylotella sp. sponge is in the Selayar Islands, South Sulawesi, Indonesia. Sponges have potential as a drug because they contain secondary metabolites. The aim study was to identify the types of secondary metabolite compounds and determine the bioactivity of Stylotella sp. compounds against MCF-7 breast cancer cells. The extraction method was used in the process of obtaining isolates because it is easy and economical. Testing the level of purity of isolates was carried out with three eluent systems which showed a single stain result. FTIR characterization results showed that pure isolates contained alkaloids which were characterized by the appearance of O-H, C-N, and C-H groups. The activity of MCF-7 cells using the colorimetric method showed an IC50 value of 14987.50 µg / mL, not toxic

17,18-dihydroxy Montecristin Compound from the Stem Bark of the Soursop (Annona muricata Linn.)

The development of natural ingredients use for conventional medicine is now in high requirement due to the traditional drugs are reasonably undemanding to be achieved. Annonaceae is one plant family which is usually utilized as medical plants in Indonesia and many other countries. One species of the family which is regularly used as customary medicine is A. muricata Linn which is well-known as soursop that comes from Caribbean, Central America, and South America. Along with the technological advancement, compounds and efficacy of soursop plant becomes popular. Annona muricata Linn. or soursop belongs to the Annonaceae family that is traditionally used to treat various diseases, such as cancer, diarrhea, convulsive, fungal and itching. The purpose of this study was to isolate and purify secondary metabolites of ethyl acetate fraction of the soursop stem bark. Research methods include extraction (maceration), fractionation and BLST test against Artemia salina. The structure of the 17.18-dihydroxy montecristin compound was determined by IR, 1H and 13C-NMR spectra HMBC and COSY. The compound had an activity to the tumor cell of murine leukemia cells P-388 with the IC50 value of 34.05 mg/mL respectively. This study found that the compound of 17.18-dihydroxy montecristin have been isolated from the stem bark of A. Muricata L. which has potential as an anticancer with the IC50 of 34.05 µg/mL

Sintesis Metil Ester dari Minyak Biji Kemiri (Aleurites Molluccana) Menggunakan Metode Ultrasonokimia

Using the fuel oil is the basic necessary in the world now. But, the raw material cannot be updated.  To ensure the availability of the fuel oil so, the newest of alternative energy is explored it. One of the ways is biodiesel which made from vegetable oil. In this research is resulted from the transesterification reaction between candlenut oil and methanol by utilizing ultrasonic equipment. This research has passed some phases, they are the determining of acid number in oil then continued by creating biodiesel from ultrasonic wave 47 kHz. Identification of FTIR and GCMS are two methods which used to analyze the component compound in biodiesel product. The conversion number that be gotten from FAME with reaction of variation time 30, 40 and 50 in succession 0,037%, 0,029% and 0,018%. The result analysis of FTIR shows some of functional groups which are special from biodiesel. While the result of GCMS analysis is known that there are 5 component compounds in biodiesel namely ester methyl palmitic acid, ester methyl olead, stearata ester methyl, linoleic ester methyl and elaidic ester methyl

Identifikasi dan Karakterisasi Senyawa Bioaktif Antikanker dari Ekstrak Etanol Kulit Batang Kayu Bitti (Vitex cofassus)

Bitti wood (Vitex cofassus) is one of the plants in Verbenaceae family and known by the people of South Sulawesi as the building material. The aims of this research  is to identify and characterize  the anticancer bioactive compound in ethanol extract of vortex Bitti wood (Vitex cofassus) and to determine the bioactivity value. This research uses extraction and fraction method, identification uses thin layer chromatography (TLC) and phytochemical test to know metabolism secunder and characterization with FTIR. The result from isolation shows that the amorf shape with 18 mg has white and yellow colour. The purification is conduted by using spectroscopy test FTIR. The result shows that the crystal has flavonoids compound which is solid with phytochemical test like positive product by using FeCl3 5%, NaOH 10% and H2SO4 P. Thick extract, fraction combination and amorf continued with toxicity test with the animal test Artemia salina Leach it uses Brine Shrimp Lethality test (BST) method. LC50 value which is gotten the three samples is thick extract 29,51 ppm, combination fraction 169,82 ppm and amorf 562,34 ppm

SENYAWA GOLONGAN STEROID DARI EKSTRAK n-HEKSANA KULIT BATANG KAYU BITTI (Vitex cofassus) DAN UJI TOKSISITAS TERHADAP Artemia salina Leach.

Penelitian telah dilakukan untuk mengidentifikasi dan mengkarakterisasi senyawa bioaktif dari kulit batang kayu bitti (Vitex cofassus), suatu tumbuhan endemik dari Sulawesi yang termasuk famili Verbenaceae. Tahapan penelitian meliputi maserasi, fraksinasi, pemurnian, identifikasi dan uji toksisitas. Ekstraksi dilakukan dengan metode maserasi menggunakan n-hexane. Tahapan identifikasi meliputi melibatkan uji warna,analisis KLT, analisis IR, sedangkan uji toksisitas menggunakan metode BSLT dengan Artemia salina Leach sebagai bioindikator. Hasil penelitian adalah senyawa dengan bentuk kristal jarum berwarna putih dengan 0,4745 gram dan analisis fitokimia menunjukkan bahwa senyawa tersebut adalah senyawa golongan steroid. Hal ini juga didukung oleh data IR yang menunjukkan gugus fungsi kelompok steroid. Uji toksisitas menunjukkan harga LC50 pada ekstrak, fraksi, dan senyawa murni berturut-turut sebesar 74,079 ug/ml, 118,850 ug/ml and 88,201 ug/ml. Data ini menunjukkan bahwa seyawa murni yang dihasilkan adalah murni